📜2,1,3-苯并噻二唑置于氢溴酸,溴体系中,化学反应 3.0H,以65%的收率获得4-溴-2,1,3-苯并噻二唑 参考文献:增强光敏性的策略:聚合和供体-受体偶数-奇效应 标题:增强光敏性的策略:聚合和供体-受体偶数-奇效应 摘要:具有供体-受体(d-A)结构的有机光敏剂(ps)设计中的一个特殊挑战是,它基于试验和错误而不是特定的规则.现在,通过提出两种提高光敏效率的有效策略来应对这些挑战:聚合促进的光敏和d-A奇偶效应.已发现共轭聚合物表现出更高的1 O 2发电效率要比它们的小分子同行高.此外,具有ad结构的ps与具有ad结构的ps相比,具有更高的光敏效率.理论计算表明,通过这些策略可以提高系统间穿越(isc)的效率.体外和体内实验均表明,所得材料可在图像引导的光动力抗癌治疗中用作光敏剂.这些准则适用于其他聚合物和小分子,以导致新ps的发展. Doi:10.1002/anie.201810326
专利信息
专利号:US-8362019-B2 优先权日:2008-02-01 标 题:Synthesis and anti-proliferative effect of substituted imidazo[4,5-b]pyrazine compounds 发明人:WINFIELD LEYTE L 权利人:SPELMAN COLLEGE; WINFIELD LEYTE L 摘要:This invention provides for compounds, compositions, and methods that involve anti-proliferative and anti-neoplastic activity in cancer cells. In particular, a series of benzimidazole, purine, imidazopyridine, and imidazopyrizine compounds having selected substitution patterns are disclosed, and the activity of various subject compounds is demonstrated. In particular, the disclosure provides for substituted imidazo[4,5-b]pyrazine compounds having the general formula n ntheir salts, pharmaceutical compositions, and methods of treatment using the subject compounds and compositions.
专利号:US-2012095038-A1 优先权日:2008-02-01 标 题:Synthesis and anti-proliferative effect of benzimidazole derivatives
专利号:US-2012095009-A1 优先权日:2008-02-01 标题 :Synthesis and anti-proliferative effect of benzimidazole derivatives
专利号:US-2012095037-A1 优先权日:2008-02-01 标题:Synthesis and anti-proliferative effect of benzimidazole derivatives
专利号:US-2012095027-A1 优先权日:2008-02-01 标题:Synthesis and anti-proliferative effect of benzimidazole derivatives
专利号:US-2011152278-A1 优先权日:2008-02-01 标 题 :Synthesis and anti-proliferative effect of benzimidazole derivatives
参考文献:10.1055/s-0036-1589008 摘要:Minami Y, Hiyama T, Komiyama T. Recent Progress in the Cross-Coupling Reaction Using Triorganosilyl-Type Reagents. Synlett. 2017 May 04;28(15):1873–84. doi: 10.1055/s-0036-1589008.