CAS: 19013-03-7; 1-(7-Hydroxy-2,2-Dimethyl-2H-Chromen-6-yl)Ethan-1-One

该化合物是一种天然的化学化合物,被归类为铬衍生物,主要来自Asteraceae家族的植物,特别是来自genus Eupatorium的植物.该化合物的特点是独特的双环结构,由连接到保温圈的苯环组成.Eupatoriaochmene展示了各种生物活动,包括抗炎,抗氧化剂和潜在的抗癌特性,这使得它对药理研究感兴趣.其溶性特性通常显示中度极性,使其能够与极地和非极地环境互动.此外,Eupatoriaromene可能对某些植物的口味和芳香图作出贡献,增强它们对草药和天然产品的吸引力.随着研究的继续进行,正在探索其化学行为,潜在应用和行动机制的全部范围,突出其在天然产品化学和医药应用中的重要性.

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合成工艺路线路线简述

    📜6-Acetyl-7-Hydroxy-2,2-Dimethylchroman-4-One置于盐酸,Sodium Tetrahydroborate,Titanium(III) Chloride,羟胺,Sodium Acetate体系中,用 乙醇 用作溶剂,化学反应生成泽兰色原烯
    参考文献:Heterocycles From Diacetyl Phenols: Synthesis Of Benzodioyrans,Acetylchromenes And Pyrano[1,2]Benzisoxazoles
    标题:Heterocycles From Diacetyl Phenols: Synthesis Of Benzodioyrans,Acetylchromenes And Pyrano[1,2]Benzisoxazoles
    摘要:
    Doi:10.3987/com-88-S135

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    主要参考文献

    参考标题:Natural Product-Like Combinatorial Libraries Based On Privileged Structures. 1. General Principles And Solid-Phase Synthesis Of Benzopyrans
    作者:K. C. Nicolaou,J. A. Pfefferkorn,A. J. Roecker,G.-Q. Cao,S. Barluenga,H. J. Mitchell |发布日期:2000.10.1
    摘要:Report A Novel Strategy For The Design And Construction Of Natural And Natural Product-Like Libraries Based On The Principle Of Privileged Structures, A Term Originally Introduced To Describe Structural Motifs Capable Of Interacting With A Variety Of Unrelated Molecular Targets. The Identification Of Such Privileged Structures In Natural Products Is Discussed, And Subsequently The 2,2-Dimethylbenzopyran

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    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    摘要:Xiao, X., Science of Synthesis: Knowledge Updates, (2023) 2, 194.
    参考文献:10.1021/np960199m
    摘要:Castañeda P, Gómez L, Mata R, Lotina-Hennsen B, Anaya AL, Bye R. Phytogrowth-inhibitory and antifungal constituents of Helianthella quinquenervis. J Nat Prod. 1996 Mar;59(3):323–6. doi: 10.1021/np960199m.
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