CAS: 1825-68-9; Chloromethoxydimethylsilane

该化合物是有机硅化合物,其特点是二甲基硅脊椎中含有氯和甲基环氧功能组,该化合物一般是淡黄色液体的无色物质,以其活性闻名,特别是由于氯硅烷组在水分中可以进行水解以形成硅醇和盐酸.氯氧二甲基硅烷经常用于硅联结剂合成,通过促进有机和无机阶段之间的结合,增强材料的粘合特性.此外,该化合物在生产各种硅酮聚合物和涂层的过程中起着先质作用,其化学结构允许应用中的多用途,包括表面改造和有机合成中的试剂.然而,由于其反应性质,应当谨慎处理,并遵循适当的安全协议,以避免接触其腐蚀性和潜在有害影响.

英文名称Chloromethoxydimethylsilane
中文名称二甲基甲氧基氯硅烷
IUPAC名称chloro-methoxy-dimethylsilane
其它别名Chlorodimethylmethoxysilane; Chloromethoxydimethylsilane; Dimethylmethoxychlorosilane; Dimethylmethoxysilylchloride; Methoxychlorodimethylsilane; Methoxydimethylchlorosilane; Methoxydimethylsilyl chloride
CAS编号1825-68-9
MFCD编号:MFCD00053901
EINECS号:626-966-9
分子式:C3H9ClOSi分子量:124.64
产品CID: 940766
产品分类化学试剂 → 硅烷试剂

相似结构搜索
产品信息参考
InChIKey: AWSNMQUTBVZKHY-UHFFFAOYSA-N
1S/C3H9ClOSi/c1-5-6(2,3)4/h1-3H3
计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数1.0

MSDS等安全信息

GHS象形图
GHS符号GHS02 & GHS05;
注释: Flame & Corrosion
危险类别易燃液体类别2
皮肤腐蚀类别1B
严重眼损伤类别1
警示词Danger(危险)
危险描述H225 |高度易燃液体和蒸气.
H314 |造成严重皮肤灼伤和眼损伤.
H318 |造成严重眼损伤.
防范说明P264b-P271-P280-P301+P330+P331-P304+P340-P305+P351+P338-P310-P363-P403+P233-P501c
UN编号UN 2985 3/PG 2
危险品标志F,C
安全声明16-26-33-36/37/39-45
危险类别码11-14-34
WGK Germany3

欧盟法规

C&L通报

上下游产品

methanol dimethylsilicon dichloride 1-chloromethyl-hexahydro-azepin-2-one methoxydimethylsilyl isothicyanatebenzoyloxy-methoxy-dimethyl-silane -methyl-phosphinBis--methyl-phosphin Cumyl(methoxydimethylsilyl)peroxid ethynylmethoxydimethylsilane

合成工艺路线路线简述

📜Methoxydimethylsilyl Cyanide置于三氯化磷体系中,用96.7%的收率获得二甲基甲氧基氯硅烷
参考文献:Organosilicon And Organophosphorus Compounds With Pseudohalide Groups. 2. Reactions Of Alkoxydimethylsilyl Cyanides With Chlorides Of Tricoordinated Phosphorus
标题:Organosilicon And Organophosphorus Compounds With Pseudohalide Groups. 2. Reactions Of Alkoxydimethylsilyl Cyanides With Chlorides Of Tricoordinated Phosphorus
摘要:Reactions Of Alkoxydimethylsilyl Cyanides With Some Chlorides Of Tricoordinated Phosphorus ("Phosphorous Chlorides") Have Been Studied. It Is Shown That,Depending On The Nature Of The Phosphorous Chloride,The Chlorine Atoms Can Either Be Substituted Only For Cyano Groups,Or For Alkoxy And Cyano Groups Simultaneously. The Results Obtained In This Work Clearly Show That Alkoxydimethylsilyl Cyanides Are More Reactive Reagents For Attaching Cyano Groups To A Phosphorus Atom Than Trimethylsilyl Cyanide.
Doi:10.1007/bf00959728

海关参考信息

2905110000-甲醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-6242614-B1
优先权日:1999-05-28
标题:Semi-synthesis of paclitaxel using dialkyldichlorosilanes
发明人：VEMISHETTI PURUSHOTHAM; GIBSON FRANCIS S; DILLON JOHN L
权利人:BRISTOL MYERS SQUIBB CO
摘要:A process for the synthesis of paclitaxel from 10-deacetylbaccatin-III which is protected at the 7-position with a dialkylalkoxysilyl protecting group having the formula â€”Si(R) 2 (ORâ€²).

专利号:CN-114805660-A
优先权日:2022-05-07
标题 :A kind of synthesis of functionalized trifluorovinyl compound and its resin preparation method

专利号:JP-2003502290-A
优先权日:1999-05-28
标题 :Semi-synthesis of paclitaxel using dialkyldichlorosilane

专利号:EP-1183250-A4
优先权日:1999-05-28
标题 :HALF SYNTHESIS OF PACLITAXEL WITH THE HELP OF DIALKYLDICHLOROSILANES

专利号:US-4593114-A
优先权日:1984-09-13
标题 :Direct process for preparing dimethylsiloxanes
发明人：LEWIS KENRICK M; KANNER BERNARD
权利人:UNION CARBIDE CORP
摘要:A process is disclosed for the direct synthesis of cyclic and oligomeric organosiloxanes, such as dimethylsiloxanes, comprising reacting a hydrocarbon ether and a hydrocarbon halide with a fluidized or agitated bed of activated silicon particles with a maximum contact time of five minutes, and continuously withdrawing products from that reaction.

专利号:EP-1183250-B1
优先权日:1999-05-28
标题:Semi-synthesis of paclitaxel using dialkyldichlorosilanes