CAS: 146397-20-8; 1-(6-((2,5-Dioxopyrrolidin-1-yl)Oxy)-6-Oxohexyl)-2-(3-(1-(6-((2,5-Dioxopyrrolidin-1-yl)Oxy)-6-Oxohexyl)-3,3-Dimethyl-5-Sulfoindolin-2-Ylidene)Prop-1-En-1-yl)-3,3-Dimethyl-3H-Indol-1-Ium-5-Sulfonate

专利信息

专利号:US-2010304368-A1
优先权日:2006-09-20
标 题:Components and method for enzymatic synthesis of nucleic acids
发明人：CHERKASOV DMITRY; BAEUML ENGLEBERT; BAEUML ELISABETH
权利人:CHERKASOV DMITRY; BAEUML ENGLEBERT; BAEUML ELISABETH
摘要:Novel methods for enzymatic synthesis of nucleic acid chains and the substrates for the same are disclosed. The methods are based on a step-wise enzymatic reaction. The sequencing of nucleic acids is an example of the use of the claimed methods.

专利号:US-12188022-B2
优先权日:2022-03-18
标题:Aptamer for specifically recognizing soluble ST2 protein and application of the same
发明人：DU JIE; WANG YUAN; LI FENGJUAN; TAN XIN; WANG XUE
权利人:BEIJING INST OF HEART LUNG AND BLOOD VESSEL DISEASES; BEIJING INST OF HEART LUNG & BLOOD VESSEL DISEASES
摘要:A nucleic acid aptamer specifically recognizing soluble ST2 protein and its application, belonging to the field of variation or genetic engineering, are described. The technical problem addressed includes how to specifically detect sST2 protein. In order to address this technical problem, nucleic acid aptamers of single-stranded DNA with nucleotide sequences are shown in SEQ ID No. 1-10, respectively. SELEX technology, combined with high-throughput sequencing technology and bioinformatics analysis, reduces the rounds of screening and obtains candidate nucleic acid aptamers, and further analyzes its affinity and specificity to obtain a nucleic acid aptamer that specifically recognizes sST2 protein. The nucleic acid aptamer has the characteristics of high specificity, high stability, convenient synthesis, and easy labeling of functional groups, and the like, and may be used for the detection of sST2 protein and the preparation of biosensors, diagnosis and prognosis of cardiovascular diseases and other products.

专利号:US-2024327448-A1
优先权日:2023-02-16
标题:Lithium reagents and their uses in solid phase synthesis
发明人：SHIN DONGWON; KIM NAMHO; YOO JONGSU
权利人:OLIX US INC
摘要:Provided herein are lithium-including reagents useful in solid phase synthesis. Provided herein are improved methods of oligonucleotide synthesis on UnySupport solid support.

专利号:US-2022411860-A1
优先权日:2015-09-28
标题:Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

专利号:US-2023160000-A1
优先权日:2015-09-28
标 题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

专利号:US-2023028388-A1
优先权日:2015-09-28
标 题 :Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis