合成目标产物 Ethyl Nonanoate 主要起始原料 1-Nonanal And Ethanol
(文献来源)合成步骤主要原料 1-Nonanal 和 Ethanol
壬酸置于氯化亚砜体系中,化学反应生成壬酸乙酯 参考文献:Synthesis And Insecticidal Activities Of 1,3,5-Trisubstituted-1,3,5-Hexahydrotriazine-2-N-Nitroimines 标题:Synthesis And Insecticidal Activities Of 1,3,5-Trisubstituted-1,3,5-Hexahydrotriazine-2-N-Nitroimines 摘要:Abstracta New Series Of 1,3,5‐trisubstituted‐1,3,5‐hexahydrotriazine‐2‐n‐nitroimines (3A-3J) Were Designed And Synthesized As Novel Neonicotinoid Analogues,And Their Structures Were Characterized By 1H NMR,Ir,Elemental Analysis And Ms. The Preliminary Bioassay Tests Showed That Most Of The Target Compounds Had Good Insecticidal Activities Against Nilaparvata Lugens As Well As Aphis Medicaginis At 500 Mg/l,While Compound 3I Had 100% Mortality Against Nilaparvata Lugens At 20 Mg/l. Doi:10.1002/cjoc.201180373
专利号:US-2007287843-A1 优先权日:2004-04-07 标题 :Methods and Intermediates for the Synthesis of Delta-9 Tetrahydrocannabinol 发明人:CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M 权利人:CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M 摘要:Processes are disclosed for the synthesis of Delta-9 tetrahydrocannabinol which result in an improved Y-THC/Y-THC ratio, and intermediates are disclosed that may be used in the synthesis of Delta-9 tetrahydrocannabinol such that improved Y-THCIY-THC ratios are achieved. The intermediates may be cyclic compounds prepared from 2-Carene. There is also provided a scaleable process for the preparation of (+)-p-menth-2-ene-1,8-diol, another intermediate used in the synthesis of delta-9-tetrahydrocannibinol.
专利号:US-9353057-B2 优先权日:2003-12-30 标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof 发明人:GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA 权利人:XENOPORT INC 摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.
专利号:US-8273790-B2 优先权日:2005-01-14 标 题:Exo-selective synthesis of himbacine analogs 发明人:THIRUVENGADAM TIRUVETTIPURAM K; SUDHAKAR ANANTHA; LIM NGIAP KIE; KWOK DAW-IONG; WU GEORGE G; WANG TAO; HUANG MINGSHENG; GREEN MICHAEL D 权利人:THIRUVENGADAM TIRUVETTIPURAM K; SUDHAKAR ANANTHA; LIM NGIAP KIE; KWOK DAW-IONG; WU GEORGE G; WANG TAO; HUANG MINGSHENG; GREEN MICHAEL D; SCHERING CORP 摘要:This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. The compounds produced thereby are useful as thrombin receptor antagonists. The chemistry disclosed herein is exemplified in the following synthesis sequence:
专利号:US-2016031800-A1 优先权日:2013-03-14 标 题:Synthesis of chiral kynurenine compounds and intermediates 发明人:TRETYAKOV ALEXANDER; DROUET KEITH E; SANDERS WILLIAM 权利人:VISTAGEN THERAPEUTICS INC 摘要:Provided are methods for the synthesis of compounds including chiral kynurenine compounds, intermediates useful for the synthesis thereof, and related compounds. For example, methods are provided for the synthesis of L-4-chlorokynurenine.
专利号:US-2023242581-A1 优先权日:2020-06-17 标题:Synthesis of a guanylate cyclase agonist by fragments based approach 发明人:SAMBASIVAM GANESH; KASTURCHAND GODHA ATUL; VENKATA BHAGYARAJ ARETI; ANNADURAI SATHYA; VEERANJANEYULU AVULA; VASANTRAO GADAKH AMOL; S JADHAV DIPAK 权利人:ANTHEM BIOSCIENCES PRIVATE LTD 摘要:The present invention provides a process for the synthesis of Plecanatide, a guanylate cyclase agonist. The process involves convergent synthesis with compounds, i.e., fragment of peptides followed by cyclization. The method provides high yield of Plecanatide with less impurities.
专利号:US-5512701-A 优先权日:1995-06-07 标题:Process for the synthesis of vinyl sulfenic acid derivatives 发明人:HOARD DAVID W; LUKE WAYNE D 权利人:LILLY CO ELI 摘要:The present invention is directed to a new process for the synthesis of vinyl sulfenic acid derivatives. These compounds are useful for the synthesis of benzo[b]thiophenes, in particular 2-aryl-benzo[b]thiophenes.
[参考文献]: Nascimento Es, Et Al. Quantitative Ester Analysis In Cachaca And Distilled Spirits By Gas Chromatography-Mass Spectrometry (Gc-Ms). J Agric Food Chem. 2008 Jul 23;56(14):5488-93. [参考文献]: Eduardo S P Nascimento, Et Al. Quantitative Ester Analysis In Cachaca And Distilled Spirits By Gas Chromatography-Mass Spectrometry (Gc-Ms). J Agric Food Chem. 2008 Jul 23;56(14):5488-93.
合成参考文献
摘要:Li, Y.; Xie, W.; Jiang, X., Science of Synthesis Knowledge Updates, (2016) 2, 27. 摘要:Fusano, A.; Ryu, I., Science of Synthesis: Multicomponent Reactions, (2013) 2, 427. 摘要:Shi, Y.; Cole-Hamilton, D. J.; Kamer, P. C. J., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 2, 205. 摘要:Adriaensen, K.; De Vos, D., Science of Synthesis, (2022) , 150. 摘要:Food and Cosmetics Toxicology., 2(327), 1964