CAS: 92-69-3; [1,1'-Biphenyl]-4-Ol

• 英文名称[1,1'-Biphenyl]-4-Ol
• 中文名称[1,1'-联苯]-4-醇
• IUPAC名称[1,1'-biphenyl]-4-ol
• 其它别名4-苯基苯酚; 4羟基联苯; P-Hydroxidiphenyl
• CAS编号92-69-3
• MFCD编号:MFCD00002347
• EINECS号:202-179-2
• 分子式:C12H10O
• 分子量:170.21
• 产品CID: 1965668
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• 产品信息参考
• InChIKey: YXVFYQXJAXKLAK-UHFFFAOYSA-N
• InChI=1S/C12H10O/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H…
• 计算化学: 氢键受体数1.0氢键供体数1.0可旋转键数1.0

物理性质

• 熔点164-166°C
• 沸点140-142°C at 10 mmHg
• 闪点166°C
• 密度1.1±0.1 g/cm3
• PH:7 (0.7g/l, H2O, 20°C)
• pKa:9.55(at 25°C)
• PSA:20.23
• LogP:3.0592
• 折射率1.605
• 蒸汽压0.0±0.7 mmHg at 25°C
• 溶解性Methanol: Soluble50mg/mL, Clear, Colorless
• 敏感性1. 能升华，使用时应穿防护服。2. 存在于烟气中。
• 外观形态白色至微黄色薄片状物
• 储存条件密封, 常温干燥保存
• 产品应用用作染料,树脂和橡胶的中间体.该品合成的红光增感,绿光增感染料是彩色影片的主要原料之一,也用作分析试剂.
• 性质描述白色针状或片状结晶.熔点164-165°C,沸点305-308°C.闪点165°C.易溶于醇和醚,溶于碱溶液.能升华.质量标准:项目指标外观白色粉末含量(HPLC)99.0％min水份0.5％max灰份0.5％max

MSDS等安全信息

• GHS象形图
• GHS符号GHS07 & GHS09;
  注释: Exclamation mark & Environment
• 危险类别皮肤腐蚀/刺激 类别2
  水生慢性毒性 类别2
  皮肤致敏 类别1B
  特定目标器官毒性 - 单次接触 类别3
  严重眼刺激 类别2
  皮肤致敏 类别1
  严重眼刺激 类别2A
  皮肤腐蚀 类别1B
• 警示词Warning(警告)
• 危险描述H315 |造成皮肤刺激.
  H411 |对水生生物有毒并具有长期持续影响.
  H317 |可能引起皮肤过敏反应.
  H335 |可能引起呼吸道刺激.
  H319 |造成严重眼刺激.
• 防范说明P261-P261-P264-P272-P272-P273-P280-P280-P302+P352-P302+P352
• 危险等级9
• UN编号UN3077
• 危险品标志Xi,N
• 包装等级III
• 安全声明26-36/37-61-36
• 危险类别码36/37/38-51/53-38
• WGK Germany2

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 4-Phenylphenol 主要起始原料 4-Iodobiphenyl
• 98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium,Lignin Solvents: Water; 0.5 H,70 °C
  标题:Palladium Nanoparticles,Stabilized By Lignin,As Catalyst For Cross-Coupling Reactions In Water
  作者:Coccia,Francesca; Tonucci,Lucia; D'Alessandro,Nicola; D'Ambrosio,Primiano; Bressan,Mario
  参考文献:Inorganica Chimica Acta 日期:2013 卷标:399 页码:12-18]
  
  5122-94-1 = 92-69-3
  反应条件:1.1 Reagents: Triethylamine,Oxygen Catalysts: Tetra-μ3-Hydroxytetra-μ3-Oxotris[μ-[4-[10,15,20-Tris(4-Carboxyphenyl)-21H,23H-Po... Solvents: Acetonitrile,Water; 24 H,Ph 7,Rt
  标题:Visible-Light,Photoredox Catalyzed,Oxidative Hydroxylation Of Arylboronic Acids Using A Metal-Organic Framework Containing Tetrakis(Carboxyphenyl)Porphyrin Groups
  作者:Toyao,Takashi; Ueno,Nana; Miyahara,Kenta; Matsui,Yasunori; Kim,Tae-Ho; Et Al
  参考文献:Chemical Communications (Cambridge 日期:2015 卷标:51(89) 页码:16103-16106]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium,Cellulose Solvents: Water; 30 Min,100 °C
  标题:Palladium Nanoparticle-Loaded Cellulose Paper: A Highly Efficient,Robust,And Recyclable Self-Assembled Composite Catalytic System
  作者:Zheng,Guangchao; Kaefer,Katharina; Mourdikoudis,Stefanos; Polavarapu,Lakshminarayana; Vaz,Belen; Et Al
  参考文献:Journal Of Physical Chemistry Letters 日期:2015 卷标:6(2) 页码:230-238]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: 1604839-72-6 (Silica-Coated Iron Oxide-Bound) Solvents: Water; 12 H,Rt -> 80 °C
  标题:A Highly Water-Dispersible/magnetically Separable Palladium Catalyst Based On A Fe3O4@sio2 Anchored Teg-Imidazolium Ionic Liquid For The Suzuki-Miyaura Coupling Reaction In Water
  作者:Karimi,Babak; Mansouri,Fariborz; Vali,Hojatollah
  参考文献:Green Chemistry 日期:2014 卷标:16(5) 页码:2587-2596]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: 1,4-Benzenediamine,Polymer With 1,3,5-Triisocyanatobenzene (Palladium Complexes) Solvents: Water; 3 H,60 °C
  标题:Urea-Based Porous Organic Frameworks: Effective Supports For Catalysis In Neat Water
  作者:Li,Liuyi; Chen,Zhilin; Zhong,Hong; Wang,Ruihu
  参考文献:Chemistry - A European Journal 日期:2014 卷标:20(11) 页码:3050-3060]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium Solvents: Water; 1 H,70 °C
  标题:Pd Nanoparticles Immobilized On Pnipam-Halloysite: Highly Active And Reusable Catalyst For Suzuki-Miyaura Coupling Reactions In Water
  作者:Hong,Myeng Chan; Ahn,Hyunseok; Choi,Myung Chan; Lee,Yongwoo; Kim,Jongsik; Et Al
  参考文献:Applied Organometallic Chemistry 日期:2014 卷标:28(3) 页码:156-161]
  
  129236-45-9 = 92-69-3
  反应条件:1.1 Catalysts: Methanesulfonic Acid Phenyl Ester Sulfatase Solvents: Water; 20 Min,Ph 7.4,25 °C
  标题:Simple Methanesulfonates Are Hydrolyzed By The Sulfatase Carbonic Anhydrase Activity
  作者:Kazancioglu,Elif Akin; Gueney,Murat; Sentuerk,Murat; Supuran,Claudiu T.
  参考文献:Journal Of Enzyme Inhibition And Medicinal Chemistry 日期:2012 卷标:27(6) 页码:880-885]
  
  = 92-69-3
  反应条件:1.1 Reagents: Potassium Hydroxide Catalysts: 2-Pyridinecarboxaldehyde (Reaction Products With Amino-Functionalized Divinylbenzene-Glycidyl Methacrylate-Styrene Copolymer,Palladium Complex),Palladium Diacetate Solvents: Isopropanol,Water; 0.33 H,70 °C
  标题:Synthesis Of Gel-Type Imino-Amino Functionalized Methacrylate-Styrene Terpolymers As Supports For Palladium Catalysts For The Suzuki-Miyaura Reaction
  作者:Bester,Karol; Bukowska,Agnieszka; Bukowski,Wiktor
  参考文献:Applied Catalysis 日期:2012 卷标:443 页码:443-444]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: (Sp-4-2)-[1,1′-Bis[bis(1,1-Dimethylethyl)Phosphino-Kp]Ferrocene]Dichloropalladiu... Solvents: Acetonitrile,Water; 1 - 2 H,60 °C
  标题:A Mild Robust Generic Protocol For The Suzuki Reaction Using An Air Stable Catalyst
  作者:Moseley,Jonathan D.; Murray,Paul M.; Turp,Edward R.; Tyler,Simon N. G.; Burn,Ross T.
  参考文献:Tetrahedron 日期:2012 卷标:68(30) 页码:6010-6017]
  
  5122-94-1 = 92-69-3
  反应条件:1.1 Reagents: Oxygen Catalysts: 2,5-Pyridinedicarboxylic Acid,Diisopropylethylamine,Nitric Acid,Indium(3+) Salt,Hydrate (3:1:4) Solvents: Ethanol; 10 H,Rt
  标题:Double Insurance Of Continuous Band Structure And N-C Layer Induced Prolonging Of Carrier Lifetime To Enhance The Long-Wavelength Visible-Light Catalytic Activity Of N-Doped In2O3
  作者:Sun,Liming; He,Xiaoxiao; Zeng,Suyuan; Yuan,Yusheng; Li,Rong; Et Al
  参考文献:Inorganic Chemistry 日期:2021 卷标:60(2) 页码:1160-1171]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Sodium Hydroxide,Tetrabutylammonium Bromide,Oxygen Catalysts: Palladium,1,4-Benzenediamine,Polymer With 1,4-Diisocyanatobenzene Solvents: Water; 1 H,60 °C
  标题:Evaluation Of Nitrogen-Based Polymeric Heterogeneous Catalysts For The Suzuki-Miyaura Cross-Coupling Reaction In Water
  作者:So,Jae Il; Hwang,Sosan; Lee,Myeong Yeon; Song,Mingyu; Baeck,Sung-Hyeon; Et Al
  参考文献:Acs Applied Polymer Materials 日期:2020 卷标:2(8) 页码:3122-3134]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium Diacetate (Complex With Bipyridyl Amide Bound On Silica) Solvents: Water; 1 H,80 °C
  标题:Organic Chemical Reaction Catalyst Supported Palladium On Reversed Phase Silica Gel Support For Forming Bi-Aryl Compound
  参考文献:Korea]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium Diacetate,1,4-Benzenedicarboxaldehyde,Polymer With 4,4′,4′′,4′′′-Methanetetrayltetrakis[b... Solvents: Methanol,Water; 20 Min,70 °C
  标题:Heterogeneous Catalysis By Covalent Organic Frameworks (Cof): Pd(Oac)2@cof-300 In Cross-Coupling Reactions
  作者:Goncalves,Raoni S. B.; De Oliveira,Alline B. V.; Sindra,Haryadylla C.; Archanjo,Braulio S.; Mendoza,Martin E.; Et Al
  参考文献:Chemcatchem 日期:2016 卷标:8(4) 页码:743-750]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Hydroxide Catalysts: Palladium Chloride Solvents: Isopropanol,Water; 6 H,80 °C
  标题:Palladium Supported On Aminopropyl-Functionalized Polymethylsiloxane Microspheres: Simple And Effective Catalyst For The Suzuki-Miyaura C-C Coupling
  作者:Zawartka,Wojciech; Pospiech,Piotr; Cypryk,Marek; Trzeciak,Anna M.
  参考文献:Journal Of Molecular Catalysis A: Chemical 日期:2015 卷标:407 页码:230-235]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium Solvents: Methanol; 5 Min,150 Psi,75 °C
  标题:Enhanced Heterogeneously Catalyzed Suzuki-Miyaura Reaction Over Siliacat Pd(0)
  作者:Pandarus,Valerica; Desplantier-Giscard,Delphine; Gingras,Genevieve; Ciriminna,Rosaria; Demma Cara,Piera; Et Al
  参考文献:Tetrahedron Letters 日期:2013 卷标:54(35) 页码:4712-4716]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium (Silica-Supported) Solvents: Ethanol; 2 H,77 °C
  标题:Efficient Screening And Library Generation In Parallel C-C Coupling Reactions Mediated By Organosilica Siliacat Palladium Catalysts
  作者:Pandarus,Valerica; Gingras,Genevieve; Beland,Francois; Ciriminna,Rosaria; Pagliaro,Mario
  参考文献:Organic Process Research & Development 日期:2012 卷标:16(1) 页码:117-122]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Palladium,Siliacat Pd Solvents: Ethanol; 2 H,Reflux
  标题:A New Class Of Heterogeneous Pd Catalysts For Synthetic Organic Chemistry
  作者:Pagliaro,Mario; Pandarus,Valerica; Beland,Francois; Ciriminna,Rosaria; Palmisano,Giovanni; Et Al
  参考文献:Catalysis Science & Technology 日期:2011 卷标:1(5) 页码:60-63]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Sodium Carbonate Catalysts: Palladium (Complexes With Triethoxysilylpropyl-Methylimidazolium Chloride And Acetate),1-Methyl-3-[3-(Triethoxysilyl)Propyl]Imidazolium Chloride (Palladium Acetate Complexes) Solvents: Dimethylformamide,Water; 25 Min,70 °C
  标题:Mesoporous Mcm-41 Supported N-Heterocyclic Carbene-Pd(Ii) Complex For Suzuki Coupling Reaction
  作者:Alam,Nazmul Md.; Sarkar,Shaheen M.
  参考文献:Reaction Kinetics 日期:2011 卷标:103(2) 页码:493-500]
  
  1124-19-2 = 92-69-3
  反应条件:1.1 Reagents: Potassium Hydroxide Catalysts: Palladium Solvents: Water; 24 H,25 °C1.2 Reagents: Hydrochloric Acid Solvents: Water
  标题:Exploring Bio-Inspired Strategies For The Production Of Noble Metal Nanocatalysts
  作者:Knecht,Marc R.; Pacardo,Dennis B.; Coppage,Ryan; Naik,Rajesh R.
  参考文献:Polymer Preprints (American Chemical Society 日期:2010 卷标:51(1) 页码:12-13]
  
  98-80-6 = 92-69-3
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: (Sp-4-3)-[2,6-Bis[(Di-1-Piperidinylphosphino-Kp)Amino]Phenyl-Kc]Chloropalladium Solvents: 1-Butanol,1,4-Dioxane,Water; 25 °C; 1 H,25 °C -> 100 °C1.2 Reagents: Water; 100 °C; 100 °C -> Rt
  标题:The 1,3-Diaminobenzene-Derived Aminophosphine Palladium Pincer Complex {c6H3[nhp(Piperidinyl)2]2Pd(Cl)} - A Highly Active Suzuki-Miyaura Catalyst With Excellent Functional Group Tolerance
  作者:Bolliger,Jeanne L.; Frech,Christian M.
  参考文献:Advanced Synthesis & Catalysis 日期:2010 卷标:352(6) 页码:1075-1080

海关参考信息

• 2908199090-其他酚的卤化衍生物
  2908999090-其他酚的硝化衍生物
  2918290000-其他含酚基羧酸
  2905199090-其他饱和一元醇
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• 详情请参考：📖 海关编码查询和海关进出口税则

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管