CAS: 539-32-2; 3-Butylpyridine

该化合物是一种三环有机化合物,其特点是在三点方位用丁基体组取代了一条环,这种黄色液体明显地因其反应性和结构多功能性,主要用作制药和农用化学合成的中间体,其烷基结构增强了有机溶剂的溶解性,便于在复杂反应中使用.该化合物在标准条件下具有中等稳定性,适合各种功能化过程.关键应用包括其在特殊化学品,催化剂和丁基体的准备中的作用.其明确界定的分子结构确保了合成途径的一贯性,有助于研究和工业环境产生可复制的结果.

结构式图片

相似化合物

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上下游产品

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合成工艺路线路线简述

    📜3-氰基吡啶置于氢氧化钾,乙醚,一水合肼,三乙二醇体系中,化学反应生成 3-丁基吡啶
    参考文献:Frank; Weatherbee,Journal Of The American Chemical Society,1948,Vol. 70,P. 3482
    标题:Frank; Weatherbee,Journal Of The American Chemical Society,1948,Vol. 70,P. 3482

    海关参考信息

    专利信息


    专利号:US-4954659-A
    优先权日:1987-10-21
    标 题 :1,4-bis (dihydroxyphenyl) butane and analogs
    发明人:PARKHURST ROBERT M; PARDINI RONALD S
    权利人:CHEMEX PHARMACEUTICALS INC
    摘要:A grignard synthesis of pharmacologically active 1,4-bis(dihydroxyphenyl)butane and analogs, as well as novel intermediates, is provided, comprising preparing a grignard reagent preferably, a 3,4-dialkoxyphenyl propyl magnesium bromide, which may be reacted with carbonyl compounds to form intermediates of desired end products, said carbonyl compounds preferably being 3,4-dialkoxybenzaldehydes. The resulting alcohol is converted to a corresponding ether or siloxy compound, at the carbonyl site. The oxy-substituent is cleaved off; and the benzene ring or rings dealkylated to leave hydroxy substituents on the rings.

    专利号:CN-113549084-A
    优先权日:2020-04-24
    标题:A kind of method for stereoselective synthesis of chiral lactone

    专利号:US-6228872-B1
    优先权日:1998-11-12
    标 题:Neurotrophic diamide and carbamate agents
    发明人:DUBOWCHIK GENE M; DITTA JONATHAN L; PROVENCAL DAVID P; DENHART DEREK J
    权利人:BRISTOL MYERS SQUIBB CO
    摘要:The present invention relates to the design, synthesis, and the peptidyl-prolyl isomerase (PPIase or rotamase) inhibitory activity of novel pyrrolidinemethyl diamide and carbamate compounds that are neurotrophic agents (i.e. compounds capable of stimulating growth or proliferation of nervous tissue) and that bind to immunophilins such as FKBP12 and inhibit their rotamase activity. This invention also relates to pharmaceutical compositions comprising these compounds.

    专利号:US-2024400400-A1
    优先权日:2021-09-16
    标题:Zeolite syntheses utilizing bis-pyridinium structure directing agents
    发明人:BURTON ALLEN W; VROMAN HILDA B; PHAM TRONG D; TEREFENKO EUGENE A
    权利人:EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY
    摘要:Various zeolites may be produced under hydrothermal synthesis conditions in the presence of a silicon atom source and a bis-pyridinium compound having a structure represented by formula (I). Q is an optionally substituted C1-C10 hydrocarbyl group and two Q may join to form a carbocyclic ring; n is an integer ranging from 0 to 5; m is an integer ranging from 0 to 5; n+m is greater than or equal to 1; and A is a spacer group containing 2 to about 10 atoms.

    专利号:CN-113549084-B
    优先权日:2020-04-24
    标题 :A kind of method of stereoselective synthesis chiral lactone

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Yusei Kashima, Et Al. Volatile Composition And Sensory Properties Of Indian Herbal Medicine-Pavonia Odorata-Used In Ayurveda. J Oleo Sci. 2014;63(2):149-58.

    合成参考文献


    摘要:Santana, V. C. S.; Munaretto, L. S.; de Lucca, E. C., Jr., Science of Synthesis Knowledge Updates, (2022) 1, 210.
    摘要:Sumino, S.; Fukuyama, T.; Ryu, I., Science of Synthesis, (2020) , 473.
    参考文献:10.1023/a:1010668521649
    摘要:Spotti M, Pompa G, Caloni F. Fumonisin B1 Metabolism by Bovine Liver Microsomes. Veterinary Research Communications. 2001 Aug;25(6):511–6. doi: 10.1023/a:1010668521649.
    参考文献:10.1007/s00216-011-5089-x
    摘要:Nutz S, Döll K, Karlovsky P. Determination of the LOQ in real-time PCR by receiver operating characteristic curve analysis: application to qPCR assays for Fusarium verticillioides and F. proliferatum. Analytical and Bioanalytical Chemistry. 2011 May 21;401(2):717–26. doi: 10.1007/s00216-011-5089-x.
    参考文献:10.1186/1749-799x-9-39
    摘要:Yan D, Song Y, Shen B, Kang P, Pei F. Magnetic resonance imaging in the tibial epiphyseal growth plate development of Wistar rat. Journal of Orthopaedic Surgery and Research. 2014 May 20;9(1):39. doi: 10.1186/1749-799x-9-39.
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