CAS: 5293-84-5; (Chloromethyl)Triphenylphosphoniumchloride

相似化合物

1034-49-7 1031-15-8 3020-28-8

上下游产品

CAS号56-23-5 四氯化碳 | CAS号603-35-0 三苯基膦 | CAS号5293-83-4 (羟基甲基)三苯基氯化鏻 | CAS号50-00-0 甲醛 | CAS号18370-19-9 1-[2-chloro-1-(... | CAS号27444-11-7 (2-chloro-1-cyc... | CAS号103774-26-1 5,9-dimethyldec... | CAS号1100-88-5 苄基三苯基氯化磷 | CAS号110637-64-4 (((dimethylcarb... | CAS号68089-86-1 (氯甲基)三苯基碘化膦 | CAS号4541-89-3 (2-chloro-1-phe... | CAS号622-25-3 (2-chlorovinyl)... | CAS号1138147-84-8 (1E,3E,5Z)-1-br... | CAS号1138147-83-7 (1E,3E,5E)-1-br...

📜(羟基甲基)三苯基氯化鏻置于氯化亚砜体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.0H,以18.0 G的收率获得产物(氯甲基)三苯基氯化磷
参考文献:The Synthesis Of Benzylphosphine Oxides Via Vicarious Nucleophilic Substitution And Alkenes Via Vns-horner-wittig Reactions
标题:The Synthesis Of Benzylphosphine Oxides Via Vicarious Nucleophilic Substitution And Alkenes Via Vns-horner-wittig Reactions
摘要:一系列取代的硝基苯与(氯甲基)二苯基氧化膦的阴离子发生反应,通过亲核取代作用反应生成取代的硝基苯基二苯基氧化膦.介绍了通过一锅替代亲核取代霍纳维蒂希反应立体选择性合成二苯乙烯的新方法.
DOI:10.1039/b206144A

专利信息

专利号:US-8067394-B2
优先权日:2006-11-17
标 题:Synthesis and biological activities of new tricyclic-bis-enones (TBEs)
发明人：HONDA TADASHI; SUNDARARAJAN CHITRA; GRIBBLE GORDON W; SPORN MICHAEL B; LIBY KAREN T
权利人:HONDA TADASHI; SUNDARARAJAN CHITRA; GRIBBLE GORDON W; SPORN MICHAEL B; LIBY KAREN T; DARTMOUTH COLLEGE
摘要:This invention describes novel tricyclic-bis-enone derivatives (TBEs), such as TBE-31, TBE-34, TBE-45 and water-soluble TBEs. The methods of preparing these compounds are also disclosed. The inventors demonstrate the ability of these new TBEs to inhibit proliferation of human myeloma cells, inhibit the induction of iNOS in cells stimulated with interferon-γ, induce heme oxygenase-1 (HO-1), induce CD11b expression—a leukemia differentiation marker, inhibit proliferation of leukemia cells, induce apoptosis in human lung cancer, and induce apoptosis in other cancerous cells. The TBEs of this invention are expected to be useful agents for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

专利号:WO-2014151181-A1
优先权日:2013-03-15
标题 :A novel method for synthesizing tbe-31
发明人：HONDA TADASHI; SAITO AKIRA; ZHENG SUQING
权利人:UNIV NEW YORK STATE RES FOUND
摘要:A process for the synthesis of (±)-(4bS,8aR,10aS)-10a-ethynyl-4b,8,8-trimethyl-3,7-dioxo-3,4b,7,8,8a,9,10,10a-octahydrophenanthrene-2,6-dicarbonitrile ('TBE-31'), which is useful for the treatment of various diseases and disorder in mammals. (±)-8a-(Hydroxymethyl)-1,4a-dimethyl-2,3,4,4a,6,7,8,8a,9,10-decahydrophenanthren-2-ol; (±)-8a-(Hydroxymethyl)-1,4a-dimethyl-4,4a,6,7,8,8a,9,10-octahydrophenanthren-2(3H)-one; (±)-(2R,4aS,8aS)-8a-(Hydroxymethyl)-1,4a-dimethyl-2,3,4,4a,6,7,8,8a,9,10-decahydrophenanthren-2-ol; (±)-(2S,4aS,8aS)-8a-(Hydroxymethyl)-1,4a-dimethyl-2,3,4,4a,6,7,8,8a,9,10-decahydrophenanthren-2-ol; and (±)-(4aS,8aS)-8a-(Hydroxymethyl)-1,4a-dimethyl-4,4a,6,7,8,8a,9,10-octahydrophenanthren-2(3H)-one (4).

专利号:DE-202024103926-U1
优先权日:2024-07-13
标题 :Composition and system for the synthesis of zirconocene dichloride catalyst for the production of indiacene A and indiacene B

专利号:US-7714012-B2
优先权日:2006-11-17
标 题 :Synthesis and biological activities of new tricyclic-bis-enones (TBEs)

专利号:US-2008261985-A1
优先权日:2006-11-17
标 题:Synthesis and biological activities of new tricyclic-bis-enones (tbes)

专利号:RU-2172740-C2
优先权日:1993-02-08
标 题 :Active component of medicinal preparation, steroid, method of its synthesis and pharmaceutical composition