CAS: 4657-58-3; (2Ar,3R,5As,5Bs,7Ar,9S,11Ar,12As)-2A,5A,8,8-Tetramethyl-3-((R)-6-Methylheptan-2-yl)Tetradecahydro-1H,12H-Cyclopenta[a]Cyclopropa[e]Phenanthren-9-Ol

该化合物是一种三球类化合物,其特点是由四环环烷结构构成的独特环球体结构,主要来自各种植物来源,特别是Astearchae家族的植物来源.Cycloartanol展示了一系列生物活动,包括潜在的抗炎和抗氧化特性,使其对药物学研究感兴趣.该化合物通常以白到清黄色晶状固体的形式出现,在水中不溶,但溶于乙醇和氯仿等有机溶剂,其分子公式反映了碳,氢和氧原子的复杂安排,有助于其不同的化学行为.Cycloartanol经常因其在植物代谢作用及其在天然产品合成和药用化学中的潜在应用而受到研究.此外,它作为合成其他生物活性化合物的前体,突出其在自然和合成化学环境中的重要性.

结构式图片

上下游产品

cycloartenyl acetate 14C-acetic acid14C-acetic acid cycloeucalenol cycloartenolcycloartanone 24,25-dihydrolanosterol 5α-Lanost-9(11)-en-3β-ol cycloartanyl acetate

合成工艺路线路线简述

    📜环阿屯醇置于platinum(Iv) Oxide 氢气,溶剂黄146体系中,化学反应生成 环木菠萝烷醇
    参考文献:3β-Amino-Verbindungen Der Cycloartan-Und Lanostanreihe
    标题:3β-Amino-Verbindungen Der Cycloartan-Und Lanostanreihe
    摘要:
    DOI:10.1016/s0040-4020(01)82910-0

    海关参考信息

    专利信息


    专利号:US-8263755-B2
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production
    发明人:FINDEIS MARK A
    权利人:FINDEIS MARK A; SATORI PHARMACEUTICALS INC
    摘要:As described herein, the present invention provides methods for preparing compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.

    专利号:US-7462470-B2
    优先权日:2005-06-17
    标 题 :Method for the producing vanillic acid and vanillin from waste residue of rice bran oil by fermentation and biotransformation
    发明人:SUN ZHIHAO; ZHENG PU; GUO XINFU; LIN GUANYU; YIN HANGHUA; WANG JUN; BAI YANBING
    权利人:ZHEJIANG HANGZHOU XINFU PHARMA
    摘要:A method for the production of vanillic acid and vanillin from waste residue (niger) of rice bran oil by microbial fermentation and biotransformation is provided. The method of the present invention comprises the steps of hydrolization of ferulic acid esters in waste residue of rice bran oil to ferulic acid and further conversion into vanillic acid using microbial strain Aspergillus niger CGMCC 0774 screened and preserved by the present inventor, followed by conversion of vanillic acid to produce vanillin using another microbial strain Pycnoporus cinnabarinus CGMCC 1115. The method for the production of vanillin according to the present invention utilizes renewable source from rice processing and alleviates the environmental pollution caused by the chemical synthesis of vanillin.

    专利号:US-2013059804-A1
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production

    专利号:EP-2073638-A2
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production

    专利号:CA-2670284-A1
    优先权日:2006-11-20
    标题:Synthesis of compounds useful as modulators of amyloid-beta production

    专利号:US-3686235-A
    优先权日:1969-10-14
    标 题:Class of liquid crystals
    发明人:NICHOLAS HAROLD J; KNAPP FURN F JR
    权利人:HAROLD J NICHOLAS; FURN F KNAPP JR
    摘要:THE CHEMICAL SYNTHESIS AND ISOLATION FROM NATURAL SOURCES OF A NEW CLASS OF CHOLESTERIC AND SMECTIC LIQUID CRYSTALS ARE DESCRIBED. THESE CONSIST OF VARIOUS FATTY ACID ESTERS OF TETRACYLIC TRIERTENES INCLUDING MEMBERS OF THE CLASS OF 9,19-CYCLOPROPANE TRITERPENES. THESE TRITERPENES INCLUDE 9,19-CYCLOLANOST-24-EN-3B-OL(CYCLOARTENOL), 4A,14A,24B-TRIMETHYL-9,19-CYCLOCHOLESTAN-3B-OL, 24E-METHYL-9,19-CYCLOLANOSTAN-3B-OL(24E-METHYL CYCLOARTANOL) AND 24-DIHYDRO LANOSTEROL AND ALL CHEMICALLY RELATED PRODUCTS.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/s0040-4039(00)90500-8
    摘要:Berti G, Bottari F, Marsili A, Morelli I, Polvani M, Mandelbaum A. 31-Norcycloartanol and cycloartanol from polypodium vulgare. Tetrahedron Letters. 1967 Jan;8(2):125–30. doi: 10.1016/s0040-4039(00)90500-8.
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