专利号:US-8263755-B2 优先权日:2006-11-20 标题:Synthesis of compounds useful as modulators of amyloid-beta production 发明人:FINDEIS MARK A 权利人:FINDEIS MARK A; SATORI PHARMACEUTICALS INC 摘要:As described herein, the present invention provides methods for preparing compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.
专利号:US-7462470-B2 优先权日:2005-06-17 标 题 :Method for the producing vanillic acid and vanillin from waste residue of rice bran oil by fermentation and biotransformation 发明人:SUN ZHIHAO; ZHENG PU; GUO XINFU; LIN GUANYU; YIN HANGHUA; WANG JUN; BAI YANBING 权利人:ZHEJIANG HANGZHOU XINFU PHARMA 摘要:A method for the production of vanillic acid and vanillin from waste residue (niger) of rice bran oil by microbial fermentation and biotransformation is provided. The method of the present invention comprises the steps of hydrolization of ferulic acid esters in waste residue of rice bran oil to ferulic acid and further conversion into vanillic acid using microbial strain Aspergillus niger CGMCC 0774 screened and preserved by the present inventor, followed by conversion of vanillic acid to produce vanillin using another microbial strain Pycnoporus cinnabarinus CGMCC 1115. The method for the production of vanillin according to the present invention utilizes renewable source from rice processing and alleviates the environmental pollution caused by the chemical synthesis of vanillin.
专利号:US-2013059804-A1 优先权日:2006-11-20 标题:Synthesis of compounds useful as modulators of amyloid-beta production
专利号:EP-2073638-A2 优先权日:2006-11-20 标题:Synthesis of compounds useful as modulators of amyloid-beta production
专利号:CA-2670284-A1 优先权日:2006-11-20 标题:Synthesis of compounds useful as modulators of amyloid-beta production
专利号:US-3686235-A 优先权日:1969-10-14 标 题:Class of liquid crystals 发明人:NICHOLAS HAROLD J; KNAPP FURN F JR 权利人:HAROLD J NICHOLAS; FURN F KNAPP JR 摘要:THE CHEMICAL SYNTHESIS AND ISOLATION FROM NATURAL SOURCES OF A NEW CLASS OF CHOLESTERIC AND SMECTIC LIQUID CRYSTALS ARE DESCRIBED. THESE CONSIST OF VARIOUS FATTY ACID ESTERS OF TETRACYLIC TRIERTENES INCLUDING MEMBERS OF THE CLASS OF 9,19-CYCLOPROPANE TRITERPENES. THESE TRITERPENES INCLUDE 9,19-CYCLOLANOST-24-EN-3B-OL(CYCLOARTENOL), 4A,14A,24B-TRIMETHYL-9,19-CYCLOCHOLESTAN-3B-OL, 24E-METHYL-9,19-CYCLOLANOSTAN-3B-OL(24E-METHYL CYCLOARTANOL) AND 24-DIHYDRO LANOSTEROL AND ALL CHEMICALLY RELATED PRODUCTS.
参考文献:10.1016/s0040-4039(00)90500-8 摘要:Berti G, Bottari F, Marsili A, Morelli I, Polvani M, Mandelbaum A. 31-Norcycloartanol and cycloartanol from polypodium vulgare. Tetrahedron Letters. 1967 Jan;8(2):125–30. doi: 10.1016/s0040-4039(00)90500-8.