CAS: 25532-45-0; Methyl (4R,4Ar,13Bs,14As)-4-Methyl-4A,5,7,8,13,13B,14,14A-Octahydro-4H-Indolo[2,3-A]Pyrano[3,4-G]Quinolizine-1-Carboxylate
该化合物是天然存在的碱性碱,属于被称为蛋白藻类的化合物类别,产自某些植物物种,特别是亚锥体家族的植物,其特点是复杂的分子结构,其中包括一个典型的多颗不露骨衍生物的双环框架. 19-Epiajmalicine展示了各种生物活动,包括潜在的抗癌和抗炎特性,这使它对药理学研究感兴趣.其行动机制往往涉及与特定生物目标的互动,这可能导致细胞过程的调节.该化合物的溶性,稳定性和再活性可因环境条件而变化,例如pH值和温度.此外,由于其自然起源,提取和净化过程可影响其研究和治疗应用的可得性和纯度.
- 英文名称Methyl (4R,4Ar,13Bs,14As)-4-Methyl-4A,5,7,8,13,13B,14,14A-Octahydro-4H-Indolo[2,3-A]Pyrano[3,4-G]Quinolizine-1-Carboxylate
- 中文名称19-表阿马碱
- IUPAC名称methyl (4R,4aR,13bS,14aS)-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate
- 其它别名16,17-Didehydro-19β-Methyl-18-Oxayohimban-16-Carboxylic Acid Methyl Ester; Mayumbine; Oxayohimban-16-Carboxylicacid, 16,17-Didehydro-19-Methyl-, Methyl Ester, (19B)-; Oxayohimban-16-Carboxylic Acid, 16,17-Didehydro-19-Methyl-, Methyl Ester, (19β)-
- CAS编号25532-45-0
- MFCD编号:MFCD20260485
- 分子式:C21H24N2O3分子量:352.43
- 产品CID: 1217020
- 产品分类天然产物 → 生物碱
物理性质
MSDS等安全信息
上下游产品
(Z)-methyl 2-((2S,12bS,E)-3-ethylidene-1,2,3,4,6,7,12,12b-°Ctahydroindolo[2,3-a]quinolizin-2-yl)-3-hydroxyacrylate tryptamine serpentine tetrahydroalstonine合成工艺路线路线简述
📜萝巴新 反应生成19-表阿马碱
参考文献:Palmisano,Giovanni; Danieli,Bruno; Lesma,Giordano,Journal Of The Chemical Society. Perkin Transactions I,1985,P. 923-926
标题:Palmisano,Giovanni; Danieli,Bruno; Lesma,Giordano,Journal Of The Chemical Society. Perkin Transactions I,1985,P. 923-926
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902200000-苯
2905122000-异丙醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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📌 第三方产品分析报告
主要参考文献
参考标题:Total Synthesis Of Racemic Ajmalicine And 19-Epi-Ajmalicine作者:Jrg Gutzwiller,Giacomo Pizzolato,Milan R. Uskokovi |发布日期:1981.7.22
摘要:Rac.-Ajmalicine (31) And 19-Epi-Ajmalicine (30) Have Been Synthesized By A Convergent Route From The Preformed D, E-Ring Moieties 25 And 27 And Tryptophyl Bromide. Two Syntheses Of The Trans-1-Benzoyl-3-Vinyl-4-Piperidineacetic Acid (13), Used In The Preparation Of 25 And 27, Are Also Described.
合成参考文献
参考文献:10.1080/10286020.2014.918109
摘要:Qi W, Yue S, Sun J, Simpkins JW, Zhang L, Yuan D. Alkaloids from the hook-bearing branch ofUncariarhynchophyllaand their neuroprotective effects against glutamate-induced HT22 cell death. Journal of Asian Natural Products Research. 2014 Jun 05;16(8):876–83. doi: 10.1080/10286020.2014.918109.
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