CAS: 2445-78-5; 2-Methylbutyl 2-Methylbutanoate

相似化合物

7452-79-1 15706-73-7 2983-38-2

上下游产品

CAS号137-32-6 2-甲基丁醇 | CAS号116-53-0 2-甲基丁酸 | CAS号96-17-3 2-甲基丁醛

2-甲基丁醇置于(Bis[(2-Diisopropylphosphino)Ethyl]Amine)Mn(Co)2体系中,化学反应 24.0H,以67%的收率获得2-甲基丁酸2-甲基丁酯
参考文献:锰钳子配合物用于无碱,无受体的醇与酯的脱氢偶联反应:发展,范围和理解
标题:锰钳子配合物用于无碱,无受体的醇与酯的脱氢偶联反应:发展,范围和理解
摘要:脂肪族pnp夹钳负载的地球上富集的锰(i)二羰基配合物可作为有效的催化剂,用于在无碱条件下将多种醇与酯进行无受体脱氢偶联.反应在纯净的条件下进行,催化剂负载适中,仅释放出h 2作为副产物.通过合成与催化循环有关的关键物质(通过x射线结构测定,多核(1 H,13 C,31 P,15 N,55Mn)NMR,红外光谱等),方法是研究与假定机理相关的基本步骤,并借助dft计算.与相关的钌和铁pnp催化剂一样,脱氢是由pnp-Mn(co)2支架的酰胺基和氨基氢化物形式之间的循环而引起的.对于将醇脱氢成醛,我们的结果表明,最高的能垒对应于氨基氢化物形式的氢释放,尽管其值接近于醇的外球脱氢成醛的值.这与钌和铁的催化体系形成鲜明对比,在钌和铁的催化体系中,与金属-配体协同作用中释放出的氢相比,将底物脱氢成醛的能源需求更少.
Doi:10.1021/acscatal.6B03554

专利信息

专利号:US-10533028-B2
优先权日:2014-09-04
标 题:Ruthenium complexes and their uses as catalysts in processes for formation and/or hydrogenation of esters, amides and related reactions
发明人：MILSTEIN DAVID; HU PENG; FOGLER ERAN; RAO JAI ANAND GARG NARAYANA
权利人:YEDA RES & DEV
摘要:The present invention relates to novel Ruthenium complexes of formulae A1-A4 and their use, inter alia, for (1) dehydrogenative coupling of alcohols to esters; (2) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones), or polyesters); (3) preparing amides from alcohols and amines—(including the preparation of polyamides (e.g., polypeptides) by reacting dialcohols and diamines and/or polymerization of amino alcohols and/or forming cyclic dipeptides from p-aminoalcohols; (4) hydrogenation of amides (including cyclic dipeptides, polypeptides and polyamides) to alcohols and amines; (5) hydrogenation of organic carbonates (including polycarbonates) to alcohols or hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (6) dehydrogenation of secondary alcohols to ketones; (7) amidation of esters (i.e., synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water and a base to form carboxylic acids; and (10) preparation of amino acids or their salts by coupling of amino alcohols with water and a base. The present, invention further relates to the use of certain known Ruthenium complexes for the preparation of amino acids or their salts from amino alcohols.