CAS: 14351-29-2; (3S,5R,8R,9R,10R,14R)-17-((S)-2-Hydroxy-6-Methylhept-5-En-2-yl)-4,4,8,10,14-Pentamethylhexadecahydro-1H-Cyclopenta[a]Phenanthren-3-Ol
该化合物是一种三肢类化合物,其特点是结构复杂,包括多个环和功能组;它来自大马树脂,通常存在于各种植物物种中,特别是Dipterocarpacaceae家族;该化合物呈现白色和黄色的黄色晶体外观,以其具有水分恐惧性而闻名,使其在水中无法溶解,但在有机溶剂中可以溶解;Dammarendiol由于其潜在的生物活动,包括反炎和抗微生物特性,在天然产品和药用化学领域引起了兴趣;它的结构具有四环形框架的特点,许多三肢类典型,有助于其稳定性和再活性;此外,Dammarondiol可以作为合成其他生物活性化合物的前体,增强其在药物研究中的重要性.
- 英文名称(3S,5R,8R,9R,10R,14R)-17-((S)-2-Hydroxy-6-Methylhept-5-En-2-yl)-4,4,8,10,14-Pentamethylhexadecahydro-1H-Cyclopenta[a]Phenanthren-3-Ol
- 中文名称达玛烯二醇II
- IUPAC名称(3S,5R,8R,9R,10R,14R)-17-((S)-2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol
- 其它别名Dammarenediol; (20S)-5α-Dammara-24-Ene-3β,20-Diol; 5α-Dammar-24-Ene-3β,20-Diol; Dammarenediol Ii; Dammar-24-Ene-3,20-Diol,(3B)-; Dammar-24-Ene-3,20-Diol, (3β)-; "(3B)-Dammar-24-Ene-3,20-Diol"
- CAS编号14351-29-2
- MFCD编号:MFCD17214902
- 分子式:C30H52O2分子量:444.74
- 产品CID: 664196
- 产品分类天然产物 → 萜类
物理性质
MSDS等安全信息
上下游产品
dipter°Carpol 4-methyl-3-pentenylmagnesium bromide (1S,4aR,4bR,7S,8aR,10aR)-7-Hydroxy-1,4b,8,8,10a-pentamethyl-1-(4-oxo-pentyl)-dodecahydro-phenanthren-2-one Phenyl-carbamic acid (3S,5R,8R,9R,10R,14S)-17-acetyl-4,4,8,10,14-pentamethyl-2,3,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester合成工艺路线路线简述
📜在 吡啶,Aluminum Oxide,氢氧化钾,氨,Lithium,对甲苯磺酸,Pyridinium Chlorochromate,[双(三氟乙酰氧基)碘]苯体系中,用 四氢呋喃,甲醇,乙二醇二甲醚,乙醚,二氯甲烷,水,异丙醇,苯 用作溶剂,化学反应 82.75H,反应生成达玛烯二醇 Ii
参考文献:A Short Enantioselective Total Synthesis Of Dammarenediol Ii
标题:A Short Enantioselective Total Synthesis Of Dammarenediol Ii
摘要:
Doi:10.1021/ja9620806
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9976167-B2
优先权日:2012-12-06
标题:Group of glycosyltransferases and use thereof
发明人：ZHOU ZHIHUA; YAN XING; FAN YUN; WANG PINGPING; WEI YONGJUN; WEI WEI; ZHANG JUN
权利人:SHANGHAI INST BIOLOGICAL SCIENCES CAS
摘要:Provided are the use of glycosyltransferases gGT25, gGT13, gGT30, gGT25-1, gGT25-3, gGT25-5, gGT29, gGT29-3, gGT29-4, gGT29-5, gGT29-6, gGT29-7, 3GT1, 3GT2, 3GT3, 3GT4 and derived polypeptides therefrom in the catalyzed glycosylation of terpenoid compounds and the synthesis of new saponins, wherein the glycosyltransferases can specifically and efficiently catalyze tetracyclic triterpenoid compound substrates at positions C-20 and/or C-6 and/or C-3 during hydroxyl glycosylation, and/or transfer the glycosyl from a glycosyl donor to the first glycosyl of the tetracyclic triterpenoid compounds at position C-3, so as to extend the sugar chain. The glycosyltransferases can also be used for constructing man-made synthetic rare ginsenosides and a variety of new ginsenosides and derivatives thereof.
专利号:CN-105671159-A
优先权日:2016-03-01
标 题:Method for Screening Key Genes of Notoginseng Saponins Synthesis Based on Metabolites and Gene Expression
专利号:CN-119286834-A
优先权日:2024-10-30
标题 :Rare ginsenoside damadienol synthesis enzyme and application thereof in preparation of dammaradienol
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1248/cpb.52.153
摘要:Akihisa T, Tokuda H, Ukiya M, Suzuki T, Enjo F, Koike K, Nikaido T, Nishino H. 3-epicabraleahydroxylactone and other triterpenoids from camellia oil and their inhibitory effects on Epstein-Barr virus activation. Chem Pharm Bull (Tokyo). 2004 Jan;52(1):153–6. doi: 10.1248/cpb.52.153.
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