CAS: 1325-37-7; Disodium,6-Oxo-5-[(4-Sulfonatophenyl)Hydrazinylidene]Naphthalene-2-Sulfonate

专利信息

专利号:US-2023313255-A1
优先权日:2020-07-15
标题:Massively Parallel Enzymatic Synthesis of Polynucleotides
发明人：HORGAN ADRIAN; LACHAIZE HENRI; VERARDO DOMIANO; GODRON XAVIER
权利人:DNA SCRIPT
摘要:The invention is directed to methods and compositions for inkjet assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions of the invention include formulations of synthesis reagents for inkjet delivery including, but not limited to, TdT coupling reaction buffers and 3′-O-protected dNTP monomers.

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人：MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:WO-2012120543-A1
优先权日:2011-03-09
标 题 :A single step process for synthesis of yellow dye -11 of consistent colour tone
发明人：KULKARNI AMOL ARVIND; JOSHI RAMESH ANNA; JOSHI ROHINI RAMESH
权利人:COUNCIL SCIENT IND RES; KULKARNI AMOL ARVIND; JOSHI RAMESH ANNA; JOSHI ROHINI RAMESH
摘要:Yellow due 11 is a useful dye with several application in the industry. The available literature in the synthesis of this dye results in non uniform colour tone. This issue in prior art is addressed by disclosing a batch as well continuous single condensation step process for synthesizing the yellow dye 11 with on-line uv monitoring system to ensure colour tone uniformity.

专利号:US-10882884-B2
优先权日:2016-05-18
标题:Stereoselective synthesis of phosphorothioate oligoribonucleotides
发明人：HALL JONATHAN; LI MEILING
权利人:ETH ZUERICH
摘要:The present invention relates to chiral phosphoramidites represented by formula (Ia) or formula (Ib) n n n n n n n n n n n n as novel monomers for the synthesis of stereodefined phosphorothioate MOE oligonucleotides. Furthermore, the present invention relates to a method for synthesizing stereodefined phosphorothioate MOE oligonucleotides using said novel chiral phosphoramidites.

专利号:WO-2024153643-A1
优先权日:2023-01-16
标 题 :Inkjet-assisted enzymatic nucleic acid synthesis
发明人：MOGHADDAM NICOLAS; ADELIZZI BEATRICE; LOMAN TESSA; VERARDO DAMIANO; RODRIGUEZ-PINZON DANIEL; HORGAN ADRIAN
权利人:DNA SCRIPT
摘要:Methods, devices, and compositions are provided for inkjet-assisted synthesis of a plurality of polynucleotides at reaction sites on a substrate using template-free polymerases, such as, terminal deoxynucleotidyl transferases (TdTs). Compositions include printable stabile formulations of synthesis reagents for inkjet delivery including, but not limited to, template-free polymerases, divalent cations, and nucleotides.

专利号:US-6777554-B2
优先权日:2001-02-05
标题 :Preparation of N-methylparoxetine and related intermediate compounds
发明人：FINKELSTEIN NINA
权利人:TEVA PHARMA
摘要:The present invention provides a process for preparing N-methylparoxetine, an intermediate in the synthesis of paroxetine, by reacting sesamol-tetrabutylammonium salt with CIPMA. The present invention is not limited to the synthesis of N-methylparoxetine, but also includes other similar compounds.