CAS: 90-65-3; Penicillicacid

化学文摘社编号90-65-3是一个独特的识别标志,便于在化学数据库中承认它.它与其他青霉素有某种结构相似性,但它的具体生物活动和行动机制可能有所不同,突出青霉素家族的多样性.

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    专利号:US-8653223-B2
    优先权日:2008-04-16
    标题:Transketalized compositions, synthesis, and applications
    发明人:SELIFONOV SERGEY; GOETZ ADAM EDWARD; JING FENG
    权利人:SELIFONOV SERGEY; GOETZ ADAM EDWARD; JING FENG; SEGETIS INC
    摘要:Ketal compounds of the structure I n nand a method of preparation of the compound from polyols and oxocarboxylates, as well as uses thereof.

    专利号:US-8546519-B2
    优先权日:2007-10-09
    标题 :Polyketal compounds, synthesis, and applications
    发明人:SELIFONOV SERGEY; ROTHSTEIN SCOTT D; WICKS DOUGLAS A; MULLEN BRIAN D; MULLEN TARA J; PRATT JASON D; WILLIAMS CHARLES T; WU CHUNYONG; ZHOU NING
    权利人:SELIFONOV SERGEY; ROTHSTEIN SCOTT D; WICKS DOUGLAS A; MULLEN BRIAN D; MULLEN TARA J; PRATT JASON D; WILLIAMS CHARLES T; WU CHUNYONG; ZHOU NING; SEGETIS INC
    摘要:The invention relates to polyketal compounds. The compounds are synthesized by the selective ketalization of oxocarboxylic acids, e.g. keto acids and semialdehydes, and esters thereof with tetrols and higher polyols that products two or more cyclic ketal ester moieties per molecule, wherein the cyclic ketal moieties are situated in a bis-, tris-, or polyketal conformation. The invention further relates to applications of these compounds and subsequent reactions thereof.

    专利号:US-2008119483-A1
    优先权日:2006-08-18
    标题:Compositions and methods for inhibiting protozoan growth
    发明人:BEVERLEY STEPHEN M; ZHANG KAI
    权利人:UNIV ST LOUIS
    摘要:The present invention provides compositions and methods for inhibiting protozoan growth comprising a synergistic combination of lipid synthesis inhibitors. In addition, the invention provides compositions and methods that are useful for the treatment of protozoan infections and the identification of potential new drugs for the treatment of protozoan infections.

    专利号:CN-106008419-B
    优先权日:2016-06-15
    标题 :Synthesis process of tetronic acid
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    主要参考文献


    1: Onodera T, Momose I, Adachi H, Yamazaki Y, Sawa R, Ohba SI, Kawada M. Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition. J Biol Chem. 2020 Sep
    25:jbc.RA120.013893. doi: 10.1074/jbc.RA120.013893. Epub ahead of print. 21(11):1391-1404. doi: 10.1111/mpp.12990. Epub 2020 Sep 23.
    3: Hu HC, Li CY, Tsai YH, Yang DY, Wu YC, Hwang TL, Chen SL, Fülöp F, Hunyadi A, Yen CH, Cheng YB, Chang FR. Secondary Metabolites and Bioactivities of Aspergillus ochraceopetaliformis Isolated from Anthurium brownii. ACS Omega. 2020 Aug 14;5(33):20991-20999. doi: 10.1021/acsomega.0c02489.

    合成参考文献


    摘要:Journal of Toxicology and Environmental Health., 7(169), 1981 []
    摘要:A3012: Umeda M, Tsutsui T, Saito M: Mutagenicity and inducibility of DNA single-strand breaks and chromosome aberrations by various mycotoxins. Gann. 1977 Oct;68(5):619-25.
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