CAS: 771-62-0; Pentafluorothiophenol

该化合物是一种氟芳烃硫醇,其特点是其强大的电子脱色特性和高度稳定性.苯环上存在5个氟原子,加强了其在核生殖替代和金属结合应用中的活性.该化合物在有机金属化学中特别宝贵,因其能形成稳定的复合体而成为过渡金属的悬浮剂.它的低pKA使它成为酸基反应和催化的有用试剂.此外,氟替代剂提高了热性和氧化性抗药性,使其适合高性能材料和特殊化学合成.五氟硫醇由于对空气和湿度的敏感性,通常在不热的条件下处理,因为对空气和湿度敏感.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

bromopentafluorobenzene Hexafluorobenzene 1-chloro-2,3,4,5,6-pentafluorobenzene pentafluorophenyl-prop-2-enyl thioethertrifluoromethyl pentafluorophenyl disulfide bis(pentafluorophenyl)trisulfane bis(pentafluorophenylmercapto)nickel

合成工艺路线路线简述

  • 合成目标产物 Pentafluorothiophenol 主要起始原料 Chloropentafluorobenzene
  • (文献来源)合成步骤主要原料 Chloropentafluorobenzene
六氟苯置于potassium Hydrosulfide体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应生成 五氟苯硫酚
参考文献:含有机氟的硫化合物:V.与氟或多氟芳硫醇,多氟戊硫醇及其衍生物的氯联合热解
标题:含有机氟的硫化合物:V.与氟或多氟芳硫醇,多氟戊硫醇及其衍生物的氯联合热解
摘要:在300-650oc下,聚氟芳硫醇,-芳硫醇及其衍生物与氯和溴发生热解反应,反应生成含氯和溴的聚氟化合物.
DOI:10.1007/s11178-006-0012-1

专利信息


专利号:US-7015176-B2
优先权日:2003-06-03
标题 :Process for the synthesis of aryl sulfurpentafluorides
发明人:BAILEY III WADE H; CASTEEL JR WILLIAM J; PESARESI RENO J; PROZONIC FRANK M
权利人:AIR PROD & CHEM
摘要:A process is described for the synthesis of an aryl sulfur pentafluoride compound. In one embodiment of the present invention, there is provided a process for preparing an aryl sulfurpentafluoride compound comprising: combining an at least one aryl sulfur compound with a fluorinating agent to at least partially react and form an intermediate aryl sulfurtrifluoride product; and exposing the intermediate aryl sulfurtrifluoride product to the fluorinating agent and optionally a fluoride source to at least partially react and form the aryl sulfurpentafluoride compound.

专利号:WO-2005100378-A1
优先权日:2004-04-13
标 题:Process for the preparation of a peptide, and compounds comprising a thioester carboxyl-activating group for use therein
发明人:EVANS DAVID JOHN
权利人:AVECIA LTD; EVANS DAVID JOHN
摘要:There is provided a process for the solid-phase synthesis of a polymer which comprises reacting an amine, secondary amine or hydroxyl group of a first monomer with a thioester on a second monomer wherein at least one the monomers is immobilised on a solid-phase support. There is also provide novel activated amino acids of Formula (1) wherein: R is an amino acid side chain a protected amino acid side chain or a peptide chain; X is an amino protecting group; and Z is an optionally substituted hydrocarbyl, and certain supported activated amino acids of Formula (5) wherein: SUPPORT is a solid support; L is a linking group; R is an amino acid side chain; a protected amino acid side chain or a peptide chain; and X3is an amino protecting group or one or more amino acids linked by amide bonds where the terminal residue bears an amino protecting group for use in said process.

专利号:EP-2104157-A1
优先权日:2006-12-29
标题 :Solution containing organic el material, method for synthesis of organic el material, compound synthesized by the synthesis method, method for formation of thin film of organic el material, thin film of organic el material, organic el element

专利号:US-2018208543-A1
优先权日:2017-01-26
标 题 :New method for synthesis of fenfluramine, and new compositions comprising it
发明人:PALOMBI GIOVANNI; ZAGAMI MICHAEL
权利人:FRAU PHARMA S R L
摘要:A new process for preparing the fenfluramine molecule and new compositions containing fenfluramine obtainable with the claimed process.

专利号:US-7749106-B2
优先权日:2006-03-30
标题 :Molded rubber material for golf ball, method of making the material and golf ball
发明人:SHINDO JUN; NANBA ATSUSHI
权利人:BRIDGESTONE SPORTS CO LTD
摘要:A molded rubber material for a golf ball is obtained by molding and vulcanizing a rubber composition composed of (a) a diene rubber, (b) an α,β-unsaturated carboxylic acid and/or a metal salt thereof, (c) an organic peroxide, and (d) an inorganic oxide. The inorganic oxide is prepared by a plasma process, a laser process or flame synthesis, has an average particle size of at most 200 nm, and is added in an amount of at least 1 wt % based on the zinc acrylate. The molded rubber material has a high hardness, a good resilience, and excellent durability.

专利号:EP-1484318-A1
优先权日:2003-06-03
标题:Process for the synthesis of aryl sulfurpentafluorides
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合成参考文献


参考文献:10.4137/aci.s6471
摘要:Kakadiya PR, Chandrashekhar TG, Ganguly S, Singh DK, Singh V. Low level determinations of methyl methanesulfonate and ethyl methanesulfonate impurities in emtricitabine active pharmaceutical ingredient by LC/MS/MS using electrospray ionization. Anal Chem Insights. 2011;6():21–8.
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