CAS: 55702-46-0; 2,3,4-Trichloro-1,1'-Biphenyl

该化合物是一种属于多氯联苯(PCBs)类别的氯化双联苯化合物,其特点是,在联苯结构结构中,特别是在2,3和4个位置上,存在三个替代氯原子,其特点是,该化合物在室内温度下一般没有颜色,不会黄色,在黄色固体中不会出现色素,而且因其疏水性而闻名,使其在水中不易溶,但在有机溶剂中也存在溶解. 2,3,4-三氯联苯表现出热稳定性和耐降解性,这助长了其在环境中的持久性.该化合物已被各种工业应用使用,包括作为电动液体和热传输媒介.然而,与其他多氯联苯一样,该化合物因其潜在的环境和健康危害,包括生物蓄积性和毒性,导致对其使用和处置的监管限制.适当的处理和处置对于减轻其对人类健康和生态系统的影响至关重要.

英文名称2,3,4-Trichloro-1,1'-Biphenyl
中文名称2,3,4-三氯-1,1'-联苯
IUPAC名称1,2,3-trichloro-4-phenylbenzene
其它别名2,3,4-Trichloro-1,1'-biphenyl; 2,3,4-Trichlorobiphenyl; PCB 21
CAS编号55702-46-0
分子式:C12H7Cl3分子量:257.54
产品CID: 1528360
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: IUYHQGMDSZOPDZ-UHFFFAOYSA-N
1S/C12H7Cl3/c13-10-7-6-9(11(14)12(10)15)8-4-2-1-3-5-8/h1-7H
计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0

相似化合物

69782-90-7 74338-24-2 32598-14-4

MSDS等安全信息

危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website.
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

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合成工艺路线路线简述

📜2,3,4-三氯苯胺,苯置于sodium Acetate,亚硝酸体系中,化学反应生成 2,3,4-三氯联苯醚
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4