CAS: 5182-44-5; 2-(3-Chlorophenyl)Ethanol

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CAS号1878-65-5 3-氯苯乙酸 | CAS号2039-85-2 3-氯苯乙烯 | CAS号766-83-6 3-氯苯乙炔 | CAS号53088-68-9 (3-氯苯基)乙酸甲酯 | CAS号75-21-8 环氧乙烷 | CAS号108-37-2 1-溴-3-氯苯 | CAS号18655-49-7 3-(3-氯苯基)-1-丙胺 | CAS号21640-47-1 3-(3-氯苯基)-丙腈 | CAS号52022-77-2 3-硝基苯乙醇 | CAS号34176-92-6 3-Chlorobibenzyl | CAS号16799-05-6 3-氯苯乙基溴 | CAS号791-28-6 三苯基氧化膦 | CAS号41904-40-9 3-氯苯乙醇 | CAS号5182-43-4 1-氯-3-(2-氯乙基)-苯

3-氯苯乙烯置于水,E.Coli Bl21 Cells Expressing Styrene Monooxygenase Encoded On Plasmid Pet28A-Stya体系中,用 Aq. Phosphate Buffer 作为反应溶剂,化学反应 24.0H,以25%的收率获得产物3-氯苯乙醇
参考文献:芳基烯烃的酶促对映选择性抗马尔科夫尼科夫水合
标题:芳基烯烃的酶促对映选择性抗马尔科夫尼科夫水合
摘要:苯乙烯单加氧酶催化芳基烯烃的对映选择性抗马尔科夫尼科夫水合,而不是环氧化,可以通过简单地从反应混合物中去除氧气来实现.具有类碳负离子中间体的酸碱机制使反应具有出色的抗马尔科夫尼科夫区域选择性.
DOI:10.1002/anie.202206472

专利信息

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:WO-2023183905-A2
优先权日:2022-03-24
标 题 :Deuterated analogs of pyrrole inhibitors of erk, synthesis thereof and intermediates thereto

专利号:US-2005240034-A1
优先权日:2002-05-07
标 题 :Artemisinin-based peroxide compounds as broad spectrum anti-infective agents
发明人：AVERY MITCHELL; MURALEEDHARAN KANNOTH M
权利人:AVERY MITCHELL; MURALEEDHARAN KANNOTH M
摘要:Described herein is the synthesis, bioassay results and utility of new C- 9 and C- 10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.

专利号:CN-107056630-A
优先权日:2017-01-23
标题 :A kind of indane derivative, its synthesis method and its application in medicine