CAS: 510-30-5; (4Ar,5R,6As,6Br,8Ar,10S,12Ar,12Br,14Bs)-5,10-Dihydroxy-2,2,6A,6B,9,9,12A-Heptamethyl-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-Icosahydropicene-4A-Carboxylic Acid

上下游产品

(2S,3S,4S,5R,6R)-6-((3S,6aR,6bS,8R,8aR,14bR)-8a-Carboxy-8-hydroxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yloxy)-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid codonoside B tragopogonoside A methyl ester rotundinoside A3β,16α-dihydroxy-olean-12-en-28-oic acid methyl ester aegiceradienol Echin°Cystsaeure-methylester primulagenin A

📜Gleditsioside C置于盐酸体系中,用 1,4-二氧六环 作为反应溶剂,化学反应 2.0H,以9 Mg的收率获得产物刺囊酸
参考文献:四个新的三萜皂苷被一种来自中华led的单萜酸酰化.
标题:四个新的三萜皂苷被一种来自中华led的单萜酸酰化.
摘要:从皂荚果的异常果实中分离出四个新的齐墩果烷型三萜糖苷,称为gleditsiosides Ad(1-4).使用现代NMR技术,包括dqf-Cosy,Hetcor,Hohaha,Hmbc和roesy实验以及ms分析以及化学方法,确定了它们的结构为3-O-β-D-吡喃吡喃糖基-(1-> 2)-α-L-阿拉伯吡喃喃糖基-(1-> 6)-赌ad-吡喃葡萄糖基齐墩果酸28-O-β-D-吡喃吡喃糖基-(1-> 3)-β-D-吡喃吡喃糖基-(1-> 4)-α-L-鼠李糖基-(1-> 2)-[((6S,2E)-6-羟基-2,6-二甲基-2,7-辛二烯酰基-(1-> 6)]-β-D-吡喃葡萄糖基酯(1);3-O-β-D-吡喃喃糖基-(1-> 2)-α-L-阿拉伯吡喃糖基-(1-> 6)-押注ad-吡喃葡萄糖基齐墩果酸28-O-β-D-吡喃木糖基-(1-> 3)-β-D-吡喃吡喃糖基-(1-> 4)-α-L-鼠李糖基-(1->
DOI:10.1021/np980441K

专利信息

专利号:WO-2024108582-A1
优先权日:2022-11-25
标题:Recombinant strain, construction method therefor, and use thereof in preparation of quillaic acid
发明人：CHOU HOWARD H; YANG JIAZENG
权利人:SHENZHEN INST OF ADV TECH CAS
摘要:Provided are a recombinant strain, a construction method therefor, and a use thereof in the preparation of quillaic acid. In the recombinant strain, a coding sequence of an msbp protein is inserted, said msbp protein being able to promote cytochrome P450 oxidase in the recombinant bacteria to form a complex, and the yield of quillaic acid with cytochrome P450 oxidase participating in synthesis is increased.

专利号:WO-2024003514-A1
优先权日:2022-06-29
标题 :Methods and compositions relating to the synthesis of the qs-7 molecule
发明人：OSBOURN ANNE; REED JAMES; ORME ANASTASIA; MARTIN LAETITIA
权利人:PLANT BIOSCIENCE LTD
摘要:The present invention relates to a biosynthetic route to precursors of the QS-7 molecule, as well as routes to make the QS-7 molecule, enzymes involved, the products produced and uses of the product.

专利号:EP-4547855-A1
优先权日:2022-06-29
标题 :Methods and compositions relating to the synthesis of the qs-7 molecule

专利号:US-12187755-B2
优先权日:2014-05-30
标题 :Minimal saponin analogues, synthesis and use thereof
发明人：GIN DAVID Y; CHEA ERIC K; FERNANDEZ-TEJADA ALBERTO; TAN DEREK S; LEWIS JASON S; GARDNER JEFFREY R; PILLARSETTY NAGAVARAKISHORE
权利人:MEMORIAL SLOAN KETTERING CANCER CENTER
摘要:Truncated triterpene saponin analogues containing a trisaccharide or tetrasaccharide ester are disclosed. Also disclosed are pharmaceutical compositions comprising truncated saponin analogues and synthetic methods of producing the truncated saponin analogues. Another aspect of the present application relates to a method for immunizing a subject, comprising administering to the subject the pharmaceutical composition comprising a minimal saponin analogue and an antigen.

专利号:CN-119790158-A
优先权日:2022-06-29
标 题 :Methods and compositions relating to the synthesis of QS-7 molecules

专利号:US-9575067-B2
优先权日:2007-05-23
标 题 :Polymeric carriers for immunohistochemistry and in situ hybridization
发明人：KOSMEDER II JERRY W; KERNAG CASEY A; JOHNSON DONALD; BIENIARZ CHRISTOPHER
权利人:VENTANA MED SYST INC
摘要:Certain disclosed embodiments of the present invention concern the synthesis, derivatization, conjugation to immunoglobulins and signal amplification based on discrete, relatively short polymers having plural reactive functional groups that react with plural molecules of interest. Reactive functional groups, such as hydrazides, may be derivatized with a variety of detectable labels, particularly haptens. The remaining reactive functional groups may be conjugated directly to a specific binding molecule, such as to the oxidized carbohydrate of the Fc region of the antibody. Disclosed conjugates display large signal amplification as compared to those based on molecules derivatized with single haptens, and are useful for assay methods, particularly multiplexed assays.