CAS: 394-59-2; 2,2,2-Trifluoro-1-(P-Tolyl)Ethanone

📜((2,2-Difluoro-1-(P-Tolyl)Vinyl)Oxy)Trimethylsilane置于selectfluor体系中,用 二氯甲烷,乙腈 作为反应溶剂,以87%的收率获得产物4-(三氟乙酰基)甲苯
参考文献:卤化合成α-卤代二氟甲基酮和[18 F]标记的三氟甲基酮的一般方法
标题:卤化合成α-卤代二氟甲基酮和[18 F]标记的三氟甲基酮的一般方法
摘要:据报道,适合于合成α-卤代二氟甲基酮的一种方便的常规卤化方法.2,2-二氟-1-芳基-1-三甲基硅氧乙烯(二氟甲硅烷基烯醇醚)(2A-e)与卤素在低温(-30至-78oc)下反应可产生高产率的α-卤代二氟甲基酮(1A-j).这一一步简单的方法对于合成[]标记的α-三氟甲基酮可能非常有用.
DOI:10.1016/s0022-1139(03)00039-3

专利信息

专利号:US-8053165-B2
优先权日:2008-03-18
标 题:Hydroxyl-containing monomer, polymer, resist composition, and patterning process
发明人：KINSHO TAKESHI; OHASHI MASAKI; HASEGAWA KOJI; WATANABE TAKERU
权利人:SHINETSU CHEMICAL CO
摘要:A hydroxyl-containing monomer of formula (1) is provided wherein R 1 is H, F, methyl or trifluoromethyl, R 2 and R 3 are monovalent C 1 -C 15 hydrocarbon groups, or R 2 and R 3 may form an aliphatic ring. The monomers are useful for the synthesis of polymers which have high transparency to radiation of up to 500 nm and the effect of controlling acid diffusion so that the polymers may be used as a base resin to formulate radiation-sensitive resist compositions having a high resolution.

专利号:US-4307024-A
优先权日:1978-03-30
标题 :1,1,1-Triaryl-2,2,2-trifluoroethanes and process for their synthesis
发明人：FROSCH ROBERT A ADMINISTRATOR; KRAY WILLIAM D; ROSSER ROBERT W
权利人:NASA; KRAY WILLIAM D; ROSSER ROBERT W
摘要:New 1,1,1-triaryl-2,2,2-trifluoroethanes in which the aryl radicals carry one or more substitutents have been prepared by condensation of trifluoroacetophenones with substituted phenyl compounds in the presence of catalytic quantities of trifluoromethylsulfonic acid. The reaction can be carried out under reflux in toluene or, for strikingly better results in certain cases, reactants are simply stirred at room temperature for about 24 to 48 hours.

专利号:US-9434968-B2
优先权日:2009-06-22
标题:Transaminase reactions
发明人：HUGHES GREGORY; DEVINE PAUL N; FLEITZ FRED J; GRAU BRENDAN T; LIMANTO JOHN; SAVILE CHRISTOPHER; MUNDORFF EMILY
权利人:CODEXIS INC
摘要:The present disclosure relates to methods of using transaminase polypeptides in the synthesis of chiral amines from prochiral ketones.

专利号:US-7863465-B2
优先权日:2006-04-03
标 题 :Antifungal agents
发明人：BALKOVEC JAMES M; BOUFFARD FRANCES AILEEN; TSE BRUNO; DROPINSKI JAMES; MENG DONGFANG; GREENLEE MARK L; PEEL MICHAEL; FAN WEIMING; MAMAI AHMED; LIU HAO; LI KEQAING
权利人:MERCK SHARP & DOHME; SCYNEXIS INC
摘要:The present invention relates to novel enfumafungin derivatives of formula I and pharmaceutically acceptable salts thereof, their synthesis, and their use as inhibitors of (1,3)-β-D-glucan synthase. The present compounds and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the present compounds and pharmaceutically acceptable salts thereof, are useful for treating or preventing antifungal infections and associated diseases and conditions.

专利号:CN-103626634-B
优先权日:2013-09-06
标题 :A kind of fluorine-containing alkyne alcohol compound and its synthesis method

专利号:CN-117143005-A
优先权日:2022-05-23
标 题 :A kind of fluoromethylbiscarbazolylmethane compound and its synthesis method