CAS: 261944-56-3; 2,4-Difluoro-5-(Trifluoromethyl)Aniline

该化合物是一种氟化芳烃衍生物,其特点是芳香环上的三氟甲基和二氟替代物,该化合物是制药和农用化学合成的多用途中间体,其电子退出组可增强活性和稳定性;多种氟烃原子的存在有助于提高亲脂性和代谢抗药性,使其对生物活性分子的设计具有价值;其高纯度和定义明确的结构确保交叉相联反应的一贯性能,如Buchwald-Hartwig电镀或Suzuki-Miyaura,由于对氧化的敏感度,该化合物通常在惰性条件下处理;该化合物适合于研究和工业应用,为先进化学实体的发展提供精确的功能化.

结构式图片

欧盟法规

C&L通报

合成工艺路线路线简述

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    专利信息


    专利号:US-4293534-A
    优先权日:1980-08-22
    标题:Molten salt synthesis of alkaline earth titanates, zirconates and their solid solutions
    发明人:ARENDT RONALD H
    权利人:GEN ELECTRIC
    摘要:A particulate mixture of an alkali metal hydroxide solvent, a reactant selected from the group consisting of titanium oxide, zirconium oxide and mixtures thereof, and an alkaline earth reactant selected from the group consisting of barium oxide, strontium oxide, and mixtures thereof, is heated to melt the alkali metal hydroxide solvent in which the reactants dissolve and react precipitating a titanate, zirconate or solid solutions thereof.

    专利号:US-4293535-A
    优先权日:1980-08-22
    标 题:Molten salt synthesis of alkaline zirconate powder
    发明人:ARENDT RONALD H
    权利人:GEN ELECTRIC
    摘要:A particulate mixture of an alkali chloride solvent salt, zirconium oxide and an alkaline earth reactant selected from the group consisting of barium oxide, strontium oxide, and mixtures thereof, is heated to melt the chloride salt solvent in which the zirconium oxide and alkaline earth reactant dissolve and react precipitating a zirconate selected from the group consisting of barium zirconate, strontium zirconate and mixtures thereof.

    专利号:JP-4120709-B2
    优先权日:1995-11-07
    标 题:Synthesis of organic diurethanes and / or polyurethanes and their use for the production of diisocyanates and / or polyisocyanates

    专利号:US-2011044876-A1
    优先权日:2007-11-26
    标题 :Low temperature metal oxide synthesis
    发明人:RIMAN RICHARD E; ATAKAN VAHIT
    权利人:UNIV RUTGERS
    摘要:A method for the decomposition of one or more metal oxide precursor compounds, at least one of which is a metal carboxylate salt, to a metal oxide or mixed metal oxide by contacting the metal oxide precursor compound or compounds with an aqueous reaction mixture at a pH, pressure and temperature effective to decompose all metal oxide precursor compounds, wherein the temperature is between about room temperature and about 350° C. and the contact duration is effective to decompose all metal oxide precursor compounds to form an essentially pure metal oxide or mixed metal oxide.

    专利号:DE-3131976-A1
    优先权日:1980-08-22
    标 题 :'MELTING SYNTHESIS OF POTAL ALKALIZATE CONCONATE'

    专利号:DE-3131977-A1
    优先权日:1980-08-22
    标 题 :'MELTING SYNTHESIS OF EARTH CALALITANATES, ZIRCONATES AND THEIR SOLID SOLUTIONS'

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