CAS: 15930-53-7; 6-Bromobenzo[d][1,3]Dioxole-5-Carbaldehyde

相似化合物

61441-09-6 60546-62-5 6642-34-8

上下游产品

N-Bromosuccinimide piperonal chloroform piperic acid 6-bromo-3,4-methylenedioxycinnamic acid 4,4'-Dimethoxybiphenyl 6-(4-methoxyphenyl)benzo[d][1,3]dioxole-5-carbaldehyde methyl 3-(1-formyl-3,4-methylenedioxy)benzoate

胡椒醛置于溴,铁粉,溶剂黄146体系中,用68%的收率获得6-溴-3,4-亚甲基二氧苯甲醛
参考文献:通过pauson-Khand反应形式的(+/-)-头孢他辛的形式合成
标题:通过pauson-Khand反应形式的(+/-)-头孢他辛的形式合成
摘要:摘要 已经开发出一条简明的路线来正式合成(+/-)-头孢他辛.分子间的pauson-Khand反应被采用以高区域选择性有效地构建环戊烯酮环. 已经开发出一条简明的路线来正式合成(+/-)-头孢他辛.分子间的pauson-Khand反应被采用以高区域选择性有效地构建环戊烯酮环.
Doi:10.1055/s-0032-1318116

专利信息

专利号:US-9650355-B2
优先权日:2013-01-31
标 题 :Method for preparation of justicidin a derivatives of arylnaphthalene lignan structure
发明人：HAM JUNGYEOB; KIM TAE JUNG; KWON HAK CHEOL; JEONG KYU HYUK; SONG JUNGHO; CHUNG BONG CHUL
权利人:KOREA INST SCI & TECH
摘要:The present disclosure relates to a novel method for preparing an arylnaphthalene lignan compound. In synthesis of arylnaphthalene lignan compounds and derivatives according to the present disclosure, a naphthalene backbone may be constructed first and an aryl group may be introduced at the final stage. Through this, various kinds of derivatives that could not be prepared from the existing methods can be synthesized effectively. Further, the synthesis method according to the present disclosure is appropriate for large-scale production.

专利号:US-6825185-B2
优先权日:2000-12-21
标题:Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
发明人：KHANAPURE SUBHASH P; GARVEY DAVID S; EARL RICHARD A; EZAWA MAIKO; FANG XINQIN; GASTON RICKY D
权利人:NITROMED INC
摘要:The invention describes novel substituted aryl compounds that are cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions comprising at least one cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or, optionally, at least one therapeutic agent, such as, steroids, nonsterodal antiinflammatory compounds (NSAID), 5-lipoxygenase (5-LO) inhibitors, leukotriene B 4 (LTB 4 ) receptor antagonists, leukotriene A 4 (LTA 4 ) hydrolase inhibitors, 5-HT agonists, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) inhibitors, H 2 antagonists, antineoplastic agents, antiplatelet agents, thrombin inhibitors, thromboxane inhibitors, decongestants, diuretics, sedating or non-sedating anti-histamines, inducible nitric oxide synthase inhibitors, opioids, analgesics, Helicobacter pylori inhibitors, proton pump inhibitors, isoprostane inhibitors, and mixtures thereof. The invention also provides novel kits comprising at least one COX-2 selective inhibitor, and, optionally, at least one nitric oxide donor, and/or, optionally, at least one therapeutic agent. The novel cyclooxygenase 2 selective inhibitors of the invention can be optionally nitrosated and/or nitrosylated. The invention also provides methods for treating inflammation, pain and fever; for treating and/or improving the gastrointestinal properties of COX-2 selective inhibitors; for facilitating wound healing; for treating and/or preventing renal toxicity or other toxicities; for treating and/or preventing other disorders resulting from elevated levels of cyclooxygenase-2; and for improving the cardiovascular profile of COX-2 selective inhibitors.

专利号:CN-114773354-B
优先权日:2022-04-08
标 题 :Simple synthesis method of Trisphaeridine

专利号:CN-114773354-A
优先权日:2022-04-08
标题 :Simple synthesis method of Trisphaeridine