CAS: 15920-93-1; (S)-2-Amino-3-(Methylamino)Propanoic Acid

该化合物是一种非蛋白性氨基酸衍生物,其特征是其手性(S)配置和二级丙基功能组,该化合物是有机合成和制药研究的宝贵中间体,特别是在开发活性分子和生物活性分子方面,其结构特征,包括甲基氨替代,增强了其在调制peptide相容和受体结合特性中的效用.该化合物通常以高纯度供应,确保研究应用的再生性.在标准实验室条件下保持稳定,与常见的混合试剂相兼容,因此成为合成化学工作流程的一个实际选择.由于功能组的再活动,建议谨慎处理.

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16012-55-8 122235-70-5 131570-56-4

上下游产品

CAS号119945-11-8 2-乙酰氨基-3-(甲基氨基)丙酸

合成工艺路线路线简述

    📜N-乙酰基-3-(甲基氨基)-L-丙氨酸 反应生成3-(N-甲基氨基)-L-丙氨酸
    参考文献:The Preparation Of L-And D-α-Amino-β-Methylaminopropionic Acids And The Identification Of The Compound Isolated From Cycas Circinalis As The L-Isomer
    标题:The Preparation Of L-And D-α-Amino-β-Methylaminopropionic Acids And The Identification Of The Compound Isolated From Cycas Circinalis As The L-Isomer
    摘要:
    Doi:10.1016/s0031-9422(00)86667-4

    海关参考信息

    专利信息


    专利号:CN-114381245-A
    优先权日:2022-01-24
    标题 :Synthesis of a hyperbranched polyquaternium amino acid intercalation inhibitor and water-based drilling fluid

    专利号:WO-2022265829-A1
    优先权日:2021-06-16
    标题:Synthetic cellular membrane chemical ionophore delivery system comprising hexa-aqua ligand compositions
    发明人:RUDE KEVIN; KRYSIAK MICHAEL; PETERSEN JASEN
    权利人:IONIC ALLIANCE HOLDINGS LLC
    摘要:Synthetic ionophores for the active carry and transport of free ions across biological membranes in vivo, comprising coordination complexes of molecules with polarized hexa-aqua and/or tetra-aqua systems of free ionic metals and ionic salts as the ionophores, useful in transporting pharmaceutical, nutrient, and personal healthcare compounds. Also described are methods of their administration, methods of their synthesis and manufacture, and the ionophore products of such synthesis and manufacturing methods.

    专利号:US-2022226371-A1
    优先权日:2021-01-13
    标题 :Synthetic Cellular Membrane Chemical Ionophore Delivery System Comprising Hexa-Aqua Ligand Compositions
    发明人:RUDE KEVIN WALTON; KRYSIAK MICHAEL KENNETH; PETERSEN JASEN ERIC
    权利人:GRUPO ION BIOTECH S A P I DE C V
    摘要:Synthetic ionophores for the active carry and transport of free ions across biological membranes in vivo, comprising coordination complexes of molecules with polarized hexa-aqua and/or tetra-aqua systems of free ionic metals and ionic salts as the ionophores, useful in transporting pharmaceutical, nutrient, and personal healthcare compounds. Also described are methods of their administration, methods of their synthesis and manufacture, and the ionophore products of such synthesis and manufacturing methods.

    专利号:US-9695191-B2
    优先权日:2009-08-05
    标题 :Conformationally constrained, fully synthetic macrocyclic compounds
    发明人:OBRECHT DANIEL; ERMERT PHILIPP; OUMOUCH SAID; LACH FRANCK; LUTHER ANATOL; MARX KARSTEN; MÖHLE KERSTIN
    权利人:OBRECHT DANIEL; ERMERT PHILIPP; OUMOUCH SAID; LACH FRANCK; LUTHER ANATOL; MARX KARSTEN; MÖHLE KERSTIN; POLYPHOR AG
    摘要:Conformationally restricted, spatially defined 12-30 membered macrocyclic ring systems of type (I) are constituted by three distinct building blocks: an aromatic template a, a conformation modulator b and a spacer moiety c as detailed in the description and the claims. Macrocycles of type (I) are readily manufactured by parallel synthesis or combinatorial chemistry. They are designed to interact with specific biological targets. In particular, they show agonistic or antagonistic activity on the motilin receptor (MR receptor), on the serotonin receptor of subtype 5-HT 2B (5-HT 2B receptor), and on the prostaglandin F2•receptor (FP receptor). They are thus potentially useful for the treatment of hypomotility disorders of the gastrointestinal tract such as diabetic gastroparesis and constipation type irritable bowl syndrome; of CNS related diseases like migraine, schizophrenia, psychosis or depression; of ocular hypertension such as associated with glaucoma and preterm labour.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.5281/zenodo.5794106
    摘要:The LOTUS Initiative for Open Natural Products Research: frozen dataset union wikidata (with metadata) | DOI:10.5281/zenodo.5794106
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