CAS: 14774-37-9; Tetrahydropyran-4-Methanol

相似化合物

101691-65-0 110238-91-0 5337-03-1

上下游产品

CAS号110238-91-0 四氢吡喃-4-羧酸甲酯 | CAS号5337-03-1 四氢吡喃-4-甲酸 | CAS号96835-17-5 四氢吡喃-4-羧酸乙酯 | CAS号36838-71-8 4-亚甲基四氢-2H-吡喃 | CAS号280-64-8 9-硼双环[3.3.1]壬烷 | CAS号130990-25-9 2-(tetrahydro-3... | CAS号77-93-0 柠檬酸三乙酯(TEC) | CAS号50675-18-8 四氢吡喃-4-甲醛 | CAS号85064-61-5 四氢吡喃-4-乙酸 | CAS号850429-50-4 4-氰甲基四氢吡喃 | CAS号132291-95-3 (4-(羟基甲基)-四氢-2H... | CAS号101691-94-5 4-碘甲基四氢吡喃 | CAS号101691-65-0 (四氢吡喃-4-基)-4-甲基甲苯磺酸 | CAS号125552-89-8 4-溴甲基四氢吡喃 | CAS号745053-49-0 (R)-2-(4-环丙烷磺酰基...

4-醛基四氢吡喃置于sodium Tetrahydroborate体系中,用 乙醇 用作溶剂,化学反应 1.0H,以53%的收率获得(四氢-2H-吡喃-4-基)甲醇
参考文献:光化学同构法制备流动性脂肪醛
标题:光化学同构法制备流动性脂肪醛
摘要:廉价和易于获得的甲醛水溶液在与不稳定的重氮化合物的同系化反应中用作甲酰化试剂,这是通过在流动光反应器中对台式稳定的恶二唑啉进行紫外线光解而实现的.合成了各种脂族醛以及相应的衍生醇和苯并咪唑.不需要过渡金属催化剂或添加剂来影响反应,该反应在室温下进行80分钟.
Doi:10.1021/acs.Joc.8B02721

专利信息

专利号:US-7825244-B2
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
发明人：BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

专利号:US-10829792-B2
优先权日:2017-03-21
标 题 :Biocatalytic synthesis of strained carbocycles
发明人：CHEN KAI; HUANG XIONGYI; KAN S B JENNIFER
权利人:CALIFORNIA INST OF TECHN
摘要:Provided herein are methods for producing products containing strained carbocycles, such as cyclopropene moieties and/or bicyclobutane moieties. The methods include combining an alkyne and a carbene precursor in the presence of a heme protein, e.g., a cytochrome P450, under conditions sufficient to form the strained carbocycle. Reaction mixtures for producing strained carbocycles are also described, as well as whole-cell catalysts comprising heme proteins and variants thereof for forming cyclopropenes, bicyclobutanes, and related products.

专利号:US-8487108-B2
优先权日:2005-11-14
标题 :Piperidinyl carbamate intermediates for the synthesis of aspartic protease inhibitors
发明人：BALDWIN JOHN J; CLAREMON DAVID A; TICE COLIN; CACATIAN SALVACION; DILLARD LAWRENCE W; ISHCHENKO ALEXEY V; YUAN JING; XU ZHENRONG; MCGEEHAN GERARD; SIMPSON ROBERT D; SINGH SURESH B; ZHAO WEI; FLAHERTY PATRICK T
权利人:BALDWIN JOHN J; CLAREMON DAVID A; TICE COLIN; CACATIAN SALVACION; DILLARD LAWRENCE W; ISHCHENKO ALEXEY V; YUAN JING; XU ZHENRONG; MCGEEHAN GERARD; SIMPSON ROBERT D; SINGH SURESH B; ZHAO WEI; FLAHERTY PATRICK T; VITAE PHARMACEUTICALS INC
摘要:The present invention is directed to aspartic protease inhibitors. Certain aspartic protease inhibitors of the invention can be represented by the following structural formula or a pharmaceutically acceptable salt thereof. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.

专利号:US-2007021436-A1
优先权日:2005-06-10
标 题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis

专利号:CA-2611219-A1
优先权日:2005-06-10
标题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis

专利号:AU-2006258056-A1
优先权日:2005-06-10
标 题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis