CAS: 123577-99-1; 3',5'-Difluoroacetophenone

相似化合物

872181-59-4 433228-88-7 692732-03-9

上下游产品

CAS号461-96-1 1-溴-3,5-二氟苯 | CAS号75-36-5 乙酰氯 | CAS号108-24-7 乙酸酐 | CAS号70-11-1 2-溴苯乙酮 | CAS号220607-75-0 2-溴-1-(3,5-二氟苯基)乙酮 | CAS号872181-59-4 1-(3,5-二氟苯基)乙醇

3,5-二氟苯甲醛置于戴斯-马丁氧化剂体系中,用 四氢呋喃,二氯甲烷 用作溶剂,化学反应 3.0H,反应生成3,5-二氟苯乙酮
参考文献:Thiazolecarboxamides And Pyridinecarboxamide Compounds Useful As Pim Kinase Inhibitors
标题:Thiazolecarboxamides And Pyridinecarboxamide Compounds Useful As Pim Kinase Inhibitors
摘要:本公开描述了噻唑和吡啶羧酰胺衍生物,它们的组成以及使用方法.这些化合物抑制pim激酶的活性,并且在治疗与pim激酶活性相关的疾病方面具有用途,例如癌症和其他疾病.

专利信息

专利号:BR-112016017679-B1
优先权日:2014-02-21
标题 :5-BENZYLISOQUINOLINE DERIVATIVE COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES, PROCESS FOR THE SYNTHESIS OF SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

专利号:US-8513241-B2
优先权日:2008-03-28
标题 :3,4-dihydro-2H-pyrazino[1,2-A]indol-1-one derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
发明人：CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; SALOM BARBARA
权利人:CERVI GIOVANNI; D ANELLO MATTEO; PAPEO GIANLUCA MARIANO ENRICO; SALOM BARBARA; NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.