CAS: 103-85-5; 1-Phenylthiourea

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CAS号103-72-0 异硫氰酸苯酯 | CAS号591-50-4 碘苯 | CAS号4921-82-8 1-苯酰基-3-苯基硫脲 | CAS号102-08-9 二苯基硫脲 | CAS号142-04-1 苯胺盐酸盐 | CAS号74734-11-5 1-(甲基二硫代羰基)咪唑 | CAS号43009-16-1 PhNHCSS-*Et3NH+ | CAS号105202-01-5 N-phenyl-5-(tri... | CAS号615-21-4 2-肼基苯并噻唑 | CAS号4921-82-8 1-苯酰基-3-苯基硫脲 | CAS号22713-55-9 N-carbamothioyl... | CAS号2117-18-2 六乙基二硅氮烷 | CAS号994-49-0 六乙基二硅氧烷 | CAS号21320-99-0 4(1H)-Pyrimidin... | CAS号103-72-0 异硫氰酸苯酯

📜硫代异氰酸苯酯置于氨体系中,用 甲醇,水 用作溶剂,化学反应 24.0H,反应生成苯基硫脲
参考文献:高效,选择性和口服生物利用度的4-噻唑-N-(吡啶-2-基)嘧啶-2-胺细胞周期蛋白依赖性激酶4和6抑制剂作为抗癌候选药物:设计,合成和评估
标题:高效,选择性和口服生物利用度的4-噻唑-N-(吡啶-2-基)嘧啶-2-胺细胞周期蛋白依赖性激酶4和6抑制剂作为抗癌候选药物:设计,合成和评估
摘要:依赖细胞周期蛋白d的激酶(cdk4和cdk6)调节细胞周期进入s期的进入,并且是抗癌药物发现的有效靶点.本文中,我们详细介绍了一系列新型的4-噻唑-N-(吡啶-2-基)嘧啶-2-胺衍生物,它们是cdk4和cdk6的高效抑制剂.药物化学优化产生了83种具有选择性的口服生物利用抑制剂分子.重复口服83可以明显抑制mv4-11急性骨髓性白血病小鼠异种移植物中的肿瘤生长,而对体重没有负面影响,并且没有任何临床毒性迹象.数据值得83作为临床开发候选者.
Doi:10.1021/acs.Jmedchem.6B01670

专利信息

专利号:WO-2025017286-A1
优先权日:2023-07-14
标 题 :Novel synthesis of colloidal quantum dot ink and applications in semiconductor devices
发明人：VASHISHTHA PARTH; HE XIN; MEHTA JOSHUA; LIU JUNPENG; VO CONG-DUAN
权利人:QUANTUM SCIENCE LTD
摘要:The present invention provides a method for producing a nanocrystal composition comprising an inorganic ligand via a one-pot synthesis. The present invention also provides nanocrystals comprising novel inorganic ligands and the use of these nanocrystals. The present invention further provides the use of the novel inorganic ligands in the preparation of nanocrystals.

专利号:US-6235910-B1
优先权日:1998-09-22
标题:Process for the preparation of imidazolidine-2, 4-diones
发明人：BELLER MATTHIAS; ECKERT MARKUS; MORADI WAHED
权利人:DEGUSSA
摘要:A process for the preparation of compounds of the general formula (I)by reacting an aldehyde compound of the general formula (II)with a urea compound of the general formula (III)in the presence of carbon monoxide and a catalytically active metal compound. Compounds of the general formula (I) are important intermediates for the synthesis of alpha-amino acids.

专利号:US-2025082793-A1
优先权日:2021-11-09
标 题 :Macrocyclic compounds and methods of making the same
发明人：CLEATOR EDWARD; MATON WILLIAM MARC; SALTER RHYS
权利人:JANSSEN BIOTECH INC
摘要:The present invention is directed to the preparation of key intermediates and synthesis of compounds (macrocyclic compounds) and pharmaceutically acceptable salts thereof, immunoconjugates, radioimmunoconjugates thereof, pharmaceutical compositions containing said compounds and immunoconjugates, radioimmunoconjugates thereof.

专利号:US-9801809-B2
优先权日:2014-05-05
标题:Compositions including a botanical extract and methods of using the same in skin whitening and skin lightening applications
发明人：RANA JATINDER; DIWAKAR GANESH; SHEN XIAOJUAN; SCHOLTEN JEFFREY; MILLER REBECCA
权利人:ACCESS BUSINESS GROUP INT LLC
摘要:Compositions for topical use and having a melanin synthesis-inhibiting activity that include an amount of a botanical extract of at least one of Aspalathus Linearis, Matricaria, Saxifraga, Astragalus, Taraxacum officinale/mongolicum, Ferula varia/foetida, Carthamus tinctorius, Sophora flavescentis , or Chrysanthemum morifolium effective to reduce melanin synthesis are described. Methods for inhibiting melanin synthesis and for skin whitening are also described.

专利号:US-10118833-B2
优先权日:2014-10-02
标 题 :Dimensionally focused nanoparticle synthesis methodology
发明人：ROBINSON RICHARD D; HANRATH TOBIAS; WILLIAMSON CURTIS; NEVERS DOUGLAS
权利人:UNIV CORNELL
摘要:A methodology for synthesizing a nanoparticle batch, such as but not limited to a metal chalcogenide nanoparticle batch and further such as but not limited to a metal sulfide nanoparticle batch is predicated upon an expectation and observation that at elevated concentrations of at least one reactant material within a heat-up nanoparticle batch synthesis method, the resulting nucleated batch comprises nanoparticles that may be dimensionally focused to provide a substantially monodisperse nanoparticle batch. The embodied methodology is also applicable to a continuous reactor. The embodied methodology also considers viscosity as a dimensionally focusing result effective variable.

专利号:US-2012184724-A1
优先权日:2009-09-22
标 题 :Protected monomers and methods of deprotection for rna synthesis
发明人：SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN
权利人:SIERZCHALA AGNIESZKA B; SMART BRIAN PHILLIP; DELLINGER DOUGLAS J; DELLINGER GERALDINE; MYERSON JOEL; TIMAR ZOLTAN; AGILENT TECHNOLOGIES INC
摘要:A nucleoside monomer that is protected by a thionocarbamate protecting group and contains one or more 2 H, 13 C, or 15 N isotopes in the ribose and/or base part is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.