专利号:US-5387681-A 优先权日:1992-08-19 标题:Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides 发明人:MILLER WILLIAM D; TAO EDDIE V P 权利人:LILLY CO ELI 摘要:This invention provides a novel process for the synthesis of bicyclic aromatic sulfonic acids employing reacting a bicyclic aromatic compound with sulfur trioxide-N,N-dimethylformamide complex in the presence of a water miscible, non-reactive solvent. The resulting sulfonic acid may be converted into the corresponding sulfonyl halide by the reaction with a thionyl halide. This invention further provides a novel process for the synthesis of bicyclic aromatic sulfonamides employing the reaction conditions described supra followed by an ammonolysis or amination.
专利号:US-2019228842-A1 优先权日:2017-11-17 标 题 :Recipe for the synthesis of metastable structures using topologically assembled precursors 发明人:JENA PURUSOTTAM; FANG HONG 权利人:UNIV VIRGINIA COMMONWEALTH 摘要:Methods of planning and executing the synthesis of metastable materials are provided. Topologically assembled precursors having potential energy surfaces in which the volumes of potential wells of certain local minima are increased are created in silico. The precursor molecules are used to synthesize, e.g. two-dimensional metastable carbon materials such as penta-graphene comprised entirely of pentagons, O-graphene comprised of five- and eight-membered rings, and R-graphene comprised of four-, six- and eight-membered rings.
专利号:WO-9856796-A1 优先权日:1997-06-09 标题 :Delivery and scavenging agents for combinatorial synthesis 发明人:BOUSSIE THOMAS; HALL KEITH A; LAPOINTE ANNE M; MURPHY VINCE; POWERS TIMOTHY; BEEK JOHANNES A M VAN 权利人:SYMYX TECHNOLOGIES INC 摘要:Delivery and scavenging agents are provided for the combinatorial synthesis of organometallic compounds in a solution or suspension, where the agents are constructed from a solid support allowing for easy separation of unreacted reagents or unwanted materials from a synthesis reaction. Use of these solid supported agents also allows otherwise unfavorable reactions to be driven to completion by the use of large excesses of reactants and minimizes the chances for competing bimolecular side reactions in parallel or rapid serial synthesis.
专利号:US-5245091-A 优先权日:1990-06-22 标 题 :Process for the preparation of 1,1-bis(chlorophenyl)-2,2,2-trichloroethanol 发明人:CASTELLA SOLA JAUME; PALENCIA ADRUBAU JAIME; COMMANDEUR RAYMOND; GORNY BERNARD 权利人:ATOCHEM ELF SA 摘要:The invention relates to a process for the synthesis of 1,1-bis(chlorophenyl)-2,2,2-trichloroethanol in (dicofol) from chlorol and chlorobenzene, in which process the acid by-products formed during the condensation reaction of the chloral and the chlorobenzene are used as reaction medium in the final step for synthesis of dicofol.
专利号:US-4289890-A 优先权日:1979-02-12 标 题:Synthesis of chloromethyldisilanes 发明人:GORDON ROY G 权利人:GORDON ROY G 摘要:1,2 Dichloro-1,1,2,2-tetramethyldisilane is synthesized in high yield and good purity starting from a crude mixture of chloromethyldisilanes formed as by-products in the manufacture of silicones. The new method uses less than half as much Grignard reagent as previous methods required. The synthesis can also be used to produce other haloalkyldisilanes such as chloropentamethyldisilane or 1,1,2 trichloro-1,2,2-trimethyldisilane.
专利号:WO-2024256370-A1 优先权日:2023-06-13 标 题 :Synthesis of glufosinate using an amidase-based process 发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.
1: Tenreiro S, Vargas RC, Teixeira MC, Magnani C, Sá-Correia I. The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin. Biochem Biophys Res Commun. 2005 Feb 18;327(3):952-9. 3: Harris RJ, Whiteoak RJ. The gas-chromatographic determination of residues of barban and its major metabolites in crops. Analyst. 1972 Apr;97(153):294-9. German. German. German.
合成参考文献
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