专利号:US-9550000-B2 优先权日:2011-09-09 标题 :Compositions, methods, and systems for the synthesis and use of imaging agents 发明人:ROBINSON SIMON P; YU MING 权利人:ROBINSON SIMON P; YU MING; LANTHEUS MEDICAL IMAGING INC 摘要:The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.
专利号:US-2022339303-A1 优先权日:2011-09-09 标题 :Compositions, methods, and systems for the synthesis and use of imaging agents
专利号:US-2008176865-A1 优先权日:2005-06-15 标 题:Substituted arylpyrazoles 发明人:BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL 权利人:PFIZER LTD 摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.
专利号:EP-3567029-A1 优先权日:2011-09-09 标 题:Compositions, methods, and systems for the synthesis and use of imaging agents
专利号:CN-104159890-A 优先权日:2011-09-09 标 题 :Compositions, methods, and systems for synthesis and use of imaging agents
专利号:CA-2848147-A1 优先权日:2011-09-09 标 题 :Compositions, methods, and systems for the synthesis and use of imaging agents
参考文献:10.1007/978-94-011-3034-9_55 摘要:Albericio F, Robles J, Fernandez-Forner D, Palom Y, Celma C, Pedroso E, Giralt E, Eritja R. NPE-resin, a new approach to the solid-phase synthesis of protected peptides and oligonucleotides. 1991. In: Peptides 1990. : Springer Netherlands; 1991.