CAS: 66356-53-4; 2-((5-((Dimethylamino)Methyl)Furan-2-yl)Thio)Ethanamine

上下游产品

CAS号15433-79-1 5-(二甲氨基)甲基-2-呋喃甲醇 | CAS号156-57-0 半胱胺盐酸盐 | CAS号870-24-6 2-氯乙胺盐酸盐 | CAS号79589-16-5 5-[[(2-acetamid... | CAS号81074-81-9 5-[(二甲氨基)甲基]-2-... | CAS号98-00-0 糠醇 | CAS号1623-88-7 5-氯甲基呋喃-2-甲醛 | CAS号1350914-20-3 5-[[(2-acetamid... | CAS号2937-53-3 2-阿氨基乙醇酯 | CAS号142744-18-1 3-N-[2-[[5-[(di... | CAS号142744-23-8 1-N-[2-[[5-[(di... | CAS号142744-25-0 N-[2-[[5-[(dime... | CAS号142744-17-0 1,3-Benzenediam... | CAS号142744-16-9 N-[2-[[5-[(dime... | CAS号142744-26-1 1-N-[2-[[5-[(di... | CAS号142744-21-6 1-N-[2-(dimethy... | CAS号66357-35-5 雷尼替丁 | CAS号74-93-1 甲硫醇 | CAS号72126-82-0 1,3-bis[2-[[5-[...

5-(二甲基氨基甲基)糠基乙醇.盐酸盐置于苄基三乙基氯化铵 Sodium Hydroxide,Sodium Thiosulfate体系中,用 乙腈 作为反应溶剂,化学反应 6.0H,反应生成 2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺
参考文献:Chachula,Stanislaw; Grynkiewicz,Grzegorz; Szczycinski,Bohdan,Polish Journal Of Chemistry,1990,Vol. 64,# 7,P. 619-622
标题:Chachula,Stanislaw; Grynkiewicz,Grzegorz; Szczycinski,Bohdan,Polish Journal Of Chemistry,1990,Vol. 64,# 7,P. 619-622

专利信息

专利号:US-4967007-A
优先权日:1989-05-10
标 题 :Improved process for the preparation of 1-substituted amino-1-substituted thio-2-nitro alkenes
发明人：DESHMUKH ABDUL R A S; BHAWAL BABURAO M; SHIRALKAR VASUDEO P; RAJAPPA SRINIVASACHARI
权利人:COUNCIL SCIENT IND RES
摘要:A process is disclosed for the manufacture of 1-substituted amino-1-substituted thio-2 nitro alkenes of the general formula: (R1NH) (R2S) Câ•?CR3 (NO2) wherein R1, R2, R3, may be same or different and may consist of hydrogen, alkyl, aryl or arylalkyl groups or combinations thereof. These alkenes are prepared by reacting a primary amine with a compound of sulfur in the presence of a primary catalyst to obtain a carbonimidodithioic acid salt which is converted to a corresponding ester which is thereafter reacted with a nitro compound in the presence of a secondary catalyst. 1-methylamino-1-methylthio-2-nitroethene is an important intermediate in the synthesis of Rantitidine and Nizatidine which are used as effective drugs in the treatment of peptic ulcers and associated gastrointestinal disorders.

专利号:US-4761413-A
优先权日:1986-12-22
标 题:1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins and use in treatment of ulcers
发明人：WACHTER MICHAEL P; KARANEWSKY DONALD S
权利人:ORTHO PHARMA CORP
摘要:The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.

专利号:US-4855426-A
优先权日:1986-12-22
标题:Process of preparing 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins
发明人：WACHTER MICHAEL P; KARANEWSKY DONALD S
权利人:ORTHO PHARMA CORP
摘要:The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.

专利号:US-5030738-A
优先权日:1986-03-28
标 题:Synthesis of antiulcer compounds
发明人：REINER ALBERTO
权利人:JANUS FARMA SRL
摘要:To synthesize molecules with antiulcer action, specifically ranitidine, niperotidine and cimetidine, having the formula: ##STR1## wherein R 1 is hydrogen or together with R 2 represents the rest of a cycloaliphatic or heterocyclic optionally substituted ring with 5 or 6 carbon atoms, R 2 represents H, alkyl, alkyl substituted with a simple or substituted aromatic ring or with a single or substituted heterocyclic ring, Ar represents a simple or substituted phenyl group, a simple or substituted heterocyclic aromatic group, N=1, 2, 3, 4, 5 or 6 and X represents CH--NO 2 , S, N--C.tbd.N, the compound (II) is prepared through the following process sequence: ##STR2## wherein Z=H, NO 2 , halogen and R 3 =--(CH 2 ) n Ar, --(CH 2 ) n --SH, --(CH 2 ) n --S--S--(CH 2 ) n , --(CH 2 ) n --S--CH 2 Ar Y being halogen. n The urea of formula ##STR3## is converted in a first stage into the corresponding carbodiimide ##STR4## by reaction with triphenylphosphine and bromine in the presence of a strong base and in a second stage is obtained the desired compound by reaction with nitromethane or with a saline derivative of cynamide.

专利号:WO-0029400-A2
优先权日:1998-11-19
标 题 :Procedure for synthesis of n-[2[[[5- [(dialkilamino) methyl]-2- furanyl] methyl]thyo] ethyl]-n'- alkyl-2-nitro1,1 alkenediamines and their hydrochlorides

专利号:US-4910198-A
优先权日:1986-12-22
标题:1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins
发明人：WACHTER MICHAEL P; KARANEWSKY DONALD S
权利人:ORTHO PHARMA CORP
摘要:The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.