CAS: 5437-98-9; N-(4-Methoxyphenyl)-3-Oxobutanamide

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CAS号141-97-9 乙酰乙酸乙酯 | CAS号104-94-9 对甲氧基苯胺 | CAS号5394-63-8 2,2,6-三甲基-4H-1,... | CAS号674-82-8 双乙烯酮 | CAS号105-45-3 乙酰乙酸甲酯 | CAS号5342-23-4 4-甲基-2-羟基-6-甲氧基喹啉 | CAS号41037-26-7 6-甲氧基-4-甲基喹啉水合物 | CAS号463-51-4 乙烯酮 | CAS号104-94-9 对甲氧基苯胺 | CAS号674-82-8 双乙烯酮 | CAS号5416-93-3 4-甲氧基苯异氰酸酯 | CAS号6340-55-2 2-氯-6-甲氧基-4-甲基-喹啉 | CAS号56-54-2 奎尼丁 | CAS号359784-21-7 6-methoxy-4-met... | CAS号359784-28-4 2-diazonio-1-(6...

甲氧苯胺置于n-甲基吗啉,三苯基膦氯金,水,Silver Trifluoromethanesulfonate,氯甲酸异丙酯体系中,用 乙酸乙酯,1,2-二氯乙烷 作为反应溶剂,化学反应 24.0H,反应生成 乙酰基乙酰对甲氧基苯胺
参考文献:金催化的n-芳基烷基酰胺的脱芳基螺环化反应合成螺内酰胺
标题:金催化的n-芳基烷基酰胺的脱芳基螺环化反应合成螺内酰胺
摘要:报道了通过n-芳基炔酰胺的脱芳香螺环化进行的合成螺内酰胺的催化氧化还原中性方法.与用于相关转化的化学计量活化剂相比,我们表明在50-80oc的二氯乙烷中使用5 Mol%的au(pph 3)cl和agotf可导致选择性螺环化,提供的产品收率为35-80. 87%.反应的底物范围是好的,给电子基团和吸电子基团在芳烃环的周围是可容忍的,并且在酰胺氮上也可被取代.该段的身份芳烃环上的-烷氧基基团是实现选择性环化的途径的关键,该环化是通过其他机制途径实现的.虽然对-甲氧基的存在导致痕量的所需螺内酰胺,但是对-叔丁氧基或对羟基底物类似物以高收率和高选择性提供了螺内酰胺.
DOI:10.1021/acs.Joc.7B03125

专利信息

专利号:US-5389524-A
优先权日:1989-07-28
标 题:Method and a system for quantitatively monitoring a chemical component dissolved in a liquid medium
发明人：LARSEN BJORN E H; VINTHER ARNE; MOLLER POUL; THORSSON JORN R; SOEBERG HENRIK; SORENSEN JESPER L; LARSEN LYKKE B
权利人:KOEGE KEMISK VAERK
摘要:PCT No. PCT/DK90/00196 Sec. 371 Date Mar. 24, 1992 Sec. 102(e) Date Mar. 24, 1992 PCT Filed Jul. 30, 1990 PCT Pub. No. WO91/02254 PCT Pub. Date Feb. 21, 1991.A method and apparatus for quantitatively monitoring a chemical component dissolved in a liquid medium utilize the creation, in a measurement cell, of an interface zone between the liquid medium and an analytical reagent or reference solution. The concentration or amount of the chemical component are determined by the measurement of a value of a measurement parameter in the interface zone, and the derivation from that value of the concentration or amount of the component in comparison with a baseline or reference value measured for the reagent or reference solution alone. Matrix effects and ghosting errors are avoided. The method and apparatus can be used advantageously for on-line optimization and control of industrial, chemical and biological processes, such as chemical reactions in progress, coupling reactions for the synthesis of azo compounds, and the monitoring of in vivo or in vitro biological systems as well as for conventional analytical purposes.