CAS: 364-22-7; 2-Fluoronicotinamide

相似化合物

3939-13-7 859164-64-0 205744-16-7

上下游产品

CAS号393-55-5 2-氟烟酸 | CAS号119899-26-2 2-氟烟酰氯 | CAS号1603-40-3 2-氨基-3-甲基吡啶 | CAS号2369-18-8 2-氟-3-甲基吡啶 | CAS号446-26-4 2-氟烟酸甲酯 | CAS号5345-47-1 2-氨基烟酸 | CAS号609-71-2 2-羟基烟酸 | CAS号10128-92-4 3-Pyridinecarbo...

📜2-氨基-3-甲基吡啶置于potassium Permanganate,Tetrafluoroboric Acid,氯化亚砜,氨,Sodium Nitrite,苯体系中,化学反应生成2-氟烟酰胺
参考文献:Synthesis Of 2-And 6-Fluoronicotinamides
标题:Synthesis Of 2-And 6-Fluoronicotinamides
摘要:
Doi:10.1021/ja01171A518

专利信息

专利号:US-12391691-B2
优先权日:2018-11-16
标题:Synthesis of key intermediate of KRAS G12C inhibitor compound
发明人：PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY
权利人:AMGEN INC
摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as

专利号:US-2025206736-A1
优先权日:2019-11-14
标题 :Synthesis of kras g12c inhibitor compound
发明人：CORBETT MICHAEL THOMAS; CAILLE SEBASTIEN
权利人:AMGEN INC
摘要:The present disclosure relates to an improved, efficient, scalable process to prepare intermediate compounds, such as 2-isopropyl-4-methylpyridin-3-amine, useful for the synthesis of compounds, such as Compound 9, for the treatment of KRAS G12C mutated cancers.

专利号:US-2023192682-A1
优先权日:2019-11-14
标题:Improved synthesis of kras g12c inhibitor compound

专利号:US-2023192681-A1
优先权日:2019-11-14
标 题 :Improved synthesis of kras g12c inhibitor compound

专利号:US-11299491-B2
优先权日:2018-11-16
标 题:Synthesis of key intermediate of KRAS G12C inhibitor compound

专利号:US-2025206735-A1
优先权日:2018-11-16
标题:Synthesis of key intermediate of kras g12c inhibitor compound