CAS: 136669-25-5; 4-Chloro-1H-Indole

专利信息

专利号:US-2013060047-A1
优先权日:2010-05-14
标 题:Novel methods for the preparation of p2x7r antagonists
发明人：BOS MICHAEL
权利人:BOS MICHAEL; AFFECTIS PHARMACEUTICALS AG
摘要:Disclosed are novel methods for the synthesis of N-substituted indol-3-yl-alkylamide compounds which act as P2X7R antagonists, said methods involving the rearrangement of an oxime intermediate.

专利号:US-7022730-B2
优先权日:2001-10-19
标题:Bis-heteroaryl alkanes as therapeutic agents
发明人：MJALLI ADNAN M M; SHAHBAZ KATHY G J
权利人:TRANSTECH PHARMA INC
摘要:This invention provides compounds which are useful as inhibitors of protein tyrosine phosphatases (PTPases). As inhibitors of PTPases the compounds of the invention are useful for the management, treatment, control and adjunct treatment of diseases in mammals mediated by PTPase activity. Such diseases include type I diabetes, type II diabetes, immune dysfunction, AIDS, autoimmunity, glucose intolerance, obesity, cancer, psoriasis, allergic diseases, infectious diseases, inflammatory diseases, diseases involving the modulated synthesis of growth hormone or the modulated synthesis of growth factors or cytokines which affect the production of growth hormone, or Alzheimer's disease.

专利号:WO-2004083202-A1
优先权日:2003-03-19
标 题:A process for the preparation of indolymaleimides
发明人：RAMAKRISHNA VENKATA SATYA NIRO; KAMBHAMPATI RAMA SASTRI; SHIRSATH VIKAS SHREEKRISHNA; JASTI VENKATESHWARLU
权利人:SUVEN LIFE SCIENCES LTD; RAMAKRISHNA VENKATA SATYA NIRO; KAMBHAMPATI RAMA SASTRI; SHIRSATH VIKAS SHREEKRISHNA; JASTI VENKATESHWARLU
摘要:The present invention relates to an improved method of synthesis for indolylmaleimides, such as symmetrical and non-symmetrical bis-indolylmaleimides as well as indolylmaleimides. The process of the present invention has advantages such as shorter reaction time along with fewer amounts of impurity. The yield and purity of the product are good and thus the process has wider industrial applicability.

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:US-9334275-B2
优先权日:2011-12-19
标题:Processes for preparing indoles
发明人：YOSHIKAI NAOHIKO; WEI YE
权利人:UNIV NANYANG TECH
摘要:Methods for the synthesis of an indole in provided. Methods comprise oxidizing a N-aryl imine in the presence of a palladium-based catalyst, an oxidant, and a solvent.

专利号:US-2621187-A
优先权日:1950-10-06
标题 :Synthesis of tryptophane and derivatives thereof
发明人：JONES REUBEN G; KORNFELD EDMUND C
权利人:LILLY CO ELI