CAS: 78-38-6; Diethyl Ethylphosphonate

上下游产品

diethyl sulfate sodium diethyl phosphite Ethylphosphonic dichloride sodium ethanolate2-Diaethylamino-fluoren ethylphosphonic acid Ethyl ethyl(trichlormethyl)phosphinat -aethyl-phosphinsaeure-aethylester(+/-)-2-Aethoxy-cyclohex-2-enyl-aethyl-phosphinsaeure-aethylester

2-溴乙基膦酸二乙酯置于sodium Hypophosphite,Air,三乙基硼体系中,用 甲醇,正己烷 作为反应溶剂,化学反应 2.0H,以87%的收率获得产物乙基磷酸二乙酯
参考文献:三乙基硼烷引发的亚磷酸酯在室温下自由基加成到烯烃中:单取代次膦酸和酯的合成.
标题:三乙基硼烷引发的亚磷酸酯在室温下自由基加成到烯烃中:单取代次膦酸和酯的合成.
摘要:描述了从次磷酸盐或酯中单取代的次膦酸(烷基亚膦酸)衍生物的新颖实用方法.以et(3)b / O(2)引发以磷为中心的自由基形成,并且该反应可在室温下于开放式烧瓶中方便地进行.与先前报道的次磷酸和次磷酸钠的自由基反应条件(过氧化物引发剂,酸催化作用,热)相反,该方法在中性条件下进行,因此可耐受各种官能团.以前无法获得的次膦酸可以一步一步由廉价的原料制备.对于单加成观测到极好的选择性,并且对称的次膦酸二烷基酯没有大量形成.单取代的次膦酸通常通过简单的萃取后处理即可获得高于90%的纯度.但是,如果取代基是极性的,则分离的产率会降低.由于衍生自次磷酸盐的自由基是亲电的,因此该反应仅限于使用富含电子的烯烃.反应条件也可用于室温下烷基卤的自由基还原,并提供了使用氢化三丁基锡的异常温和和环保的替代方法.反应条件的显着温和性质使敏感的次磷酸烷基酯发生自由基反应,在这种情况下,催化量的et(3)b足以以合理
DOI:10.1021/jo015876I

专利信息

专利号:US-5473093-A
优先权日:1995-01-10
标题 :Process for the synthesis of diethyl ethylphosphonate
发明人：JAFFE FRED
权利人:AKZO NOBEL NV
摘要:Diethyl ethylphosphonate is formed by the catalytic rearrangement of triethyl phosphite in a reaction medium at elevated temperature, preferably using an ethyl iodide as the rearrangement catalyst, employing a heel of diethyl ethylphosphonate in the reaction medium when the reaction is begun with maintaining of the reaction medium at a temperature above the boiling point of the triethyl phosphite (for example, a temperature of from about 175 DEG C. to about 185 DEG C.) and addition of the triethyl phosphite to the reaction medium at a rate slow enough to maintain that temperature.

专利号:WO-2012035303-A2
优先权日:2010-09-17
标题 :A novel process for synthesis of ramelteon, and key intermediates for the synthesis of ramelteon

专利号:US-11862794-B2
优先权日:2020-05-06
标题:Cost effective synthesis of oxide materials for lithium ion batteries

专利号:US-2024351913-A1
优先权日:2020-05-06
标 题 :Cost effective synthesis of oxide materials for lithium ion batteries

专利号:US-12211999-B2
优先权日:2020-05-06
标题:Cost effective synthesis of oxide materials for lithium ion batteries
发明人：XIAO JIE; BI YUJING
权利人:BATTELLE MEMORIAL INSTITUTE
摘要:Methods for synthesizing single crystalline Ni-rich cathode materials are disclosed. The Ni-rich cathode material may have a formula LiNi X Mn y M z Col 1-x-y-z O 2 , where M represents one or more dopant metals, x≥0.6, 0.01≤y<0.2, 0≤z≤0.05, and x+y+z≤1.0. The methods are cost-effective, and include methods for solid-state, molten-salt, and flash-sintering syntheses.

专利号:US-2024088382-A1
优先权日:2020-05-06
标题 :Cost effective synthesis of oxide materials for lithium ion batteries