📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于硫酸体系中,化学反应生成 α-槐糖一水合物 参考文献:Rabate; Dussy,Bulletin De La Societe De Chimie Biologique,1938,Vol. 20,P. 467,468 标题:Rabate; Dussy,Bulletin De La Societe De Chimie Biologique,1938,Vol. 20,P. 467,468
专利号:US-2006293508-A1 优先权日:2005-06-08 标题:Stabilization of triflated compounds 发明人:MAJOR MICHAEL; PETERSON ROBERT; KOSINSKI SZYMON 权利人:MAJOR MICHAEL; PETERSON ROBERT; KOSINSKI SZYMON 摘要:Described are novel processes for the synthesis triflated sugars. These sugars are useful for the production of compounds, such as D-1-deoxynojirimycin (DNJ) and D-1-deoxygalactonojirimycin (DGJ). In particular, described is a multi-kilogram scale stabilization method for the synthesis of imino sugars.
专利号:US-2024199566-A1 优先权日:2022-11-16 标题:Catalytic synthesis of delta-valerolactone (dvl) from furfural-derived 2-hydroxytetrahydropyran (hthp) 发明人:HUBER GEORGE; DASTIDAR RAKA; JOHNSTONE SAM; MCCLELLAND DANIEL 权利人:WISCONSIN ALUMNI RES FOUND 摘要:A method to make delta-valerolactone (“DVLâ€?) by dehydrogenating 2-hydroxytetrahydropyran (“HTHPâ€?). The HTHP is contacted with a supported-metal catalyst for a time, at a temperature, and at a pressure wherein at least a portion of the HTHP is converted to DVL via dehydrogenation of the HTHP. The HTHP may be derived from biomass. Thus, the method yields DVL without requiring a petroleum-based feedstock.
专利号:US-2017204442-A1 优先权日:2014-05-29 标题 :Enzymatic synthesis of soluble glucan fiber 发明人:DICOSIMO ROBERT; CHENG QIONG; ELIOT ANDREW C; OUWEHAND ARTHUR; PAYNE MARK S; YOU ZHENG 权利人:DU PONT 摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.
专利号:US-2023278976-A1 优先权日:2021-07-05 标题:Synthesis Of Beta-Glycolipid Compounds 发明人:BOXLEY CHETT; STOLLEY RYAN; BRUGGEMAN ROBERT 权利人:GLYCOSURF INC 摘要:Methods of forming a glycolipid are disclosed. A method may include glycosylating a sugar with a beta-hydroxyester using BF3-L as a glycosylation promoter. L may include one or more of Diethylether, Tetrahydrofurn, Dimethyle Sulfide, or combinations thereof. The beta-hydroxyester may include a carbon length ranging from C2 to C24. The sugar may be a protected sugar that includes peracetylated-rhamnose, peracetylated-xylose, peracetylated-glucose, peracetylated-galactose or combinations thereof. The beta-hydroxyester and sugar may be combined in a reaction vessel to form a mixture. A solvent may be added to the mixture to substantially dissolve the mixture. The glycosylation promoter may be added to the solution such that the solution is maintained withing a desired temperature range.
专利号:US-11473116-B2 优先权日:2018-02-23 标题 :Synthesis of glucan comprising alpha-1,3 glycosidic linkages with phosphorylase enzymes 发明人:YU ZHEYONG; KRALJ SLAVKO; ZHANG ZHENGHONG; HOWE LAURIE A 权利人:NUTRITION & BIOSCIENCES USA 4 INC 摘要:Reaction compositions are disclosed herein comprising at least water, beta-glucose -1-phosphate (beta-G1P), an acceptor molecule, and an alpha-1,3-glucan phosphorylase enzyme. These reactions can synthesize oligosaccharides and polysaccharides with alpha-1,3 glycosidic linkages. Further disclosed are alpha-1,3-glucan phosphorylase enzymes and methods of use thereof.
专利号:US-10022366-B2 优先权日:2013-04-23 标 题:Extending and maintaining micropore viability of microneedle treated skin with lipid biosynthesis inhibitors for sustained drug delivery 发明人:STINCHCOMB AUDRA L; GHOSH PRIYANKA 权利人:STINCHCOMB AUDRA L; GHOSH PRIYANKA; UNIV MARYLAND; UNIV KENTUCKY RES FOUND 摘要:Microneedles and their use as a physical skin permeation enhancement technique facilitate drug delivery across the skin in therapeutically relevant concentrations. Micropores created in the skin by MNs reseal because of normal healing processes of the skin, thus limiting the duration of the drug delivery window. Pore lifetime enhancement strategies can increase effectiveness of MNs as a drug delivery mechanism by prolonging the delivery window. Fluvastatin (FLU) was used to enhance pore lifetime by inhibiting the synthesis of cholesterol, a major component of the stratum corneum lipids. The skin recovered within a 30-45-min time period following the removal of occlusion, and there was no significant irritation observed due to the treatment compared to the control sites. Thus, it can be concluded that localized skin treatment with FLU can be used to extend micropore lifetime and deliver drugs for up to 7 days across MN-treated skin.
1: Tanaka N, Nakajima M, Aramasa H, Nakai H, Taguchi H, Tsuzuki W, Komba S. Synthesis of three deoxy-sophorose derivatives for evaluating the requirement of hydroxy groups at position 3 and/or 3' of sophorose by 1,2-β-oligoglucan phosphorylases. Carbohydr Res. 2018 Oct;468:13-22. doi: 10.1016/j.carres.2018.08.005. Epub 2018 Aug 12. doi: 10.1016/j.carres.2015.12.001. Epub 2016 Jan 7. doi: 10.1002/tcr.201600085. Epub 2016 Nov 25. Review. doi: 10.1155/2018/1974151. eCollection 2018. Review. 6: Huang TT, Wages JM. New-to-nature sophorose analog: a potent inducer for gene expression in Trichoderma reesei. Enzyme Microb Technol. 2016 Apr;85:44-50. doi: 10.1016/j.enzmictec.2016.01.003. Epub 2016 Jan 18. doi: 10.1186/s12866-015-0536-z. 8: Dos Santos Castro L, Pedersoli WR, Antoniêto ACC, Steindorff AS, Silva-Rocha R, Martinez-Rossi NM, Rossi A, Brown NA, Goldman GH, Faça VM, Persinoti GF, Silva RN. Comparative metabolism of cellulose, sophorose and glucose in Trichoderma reesei using high-throughput genomic and proteomic analyses. Biotechnol Biofuels. 2014 Mar 21;7(1):41. doi: 10.1186/1754-6834-7-41.
合成参考文献
参考文献:10.1016/j.jbiotec.2018.05.002 摘要:Xia Y, Yang L, Xia L. Preparation of a novel soluble inducer by cellobiase-release microcapsules and its application in cellulase production. J Biotechnol. 2018 Aug 10;279():22–6. doi: 10.1016/j.jbiotec.2018.05.002.