CAS: 5331-48-6; N-(N-Propyl)Acetamide

相似化合物

13434-12-3 14303-96-9 16423-52-2

上下游产品

CAS号623-40-5 (NE)-N-pentan-2... | CAS号64-19-7 冰醋酸 | CAS号108-03-2 1-硝基丙烷 | CAS号107-10-8 丙胺 | CAS号75-36-5 乙酰氯 | CAS号75-05-8 乙腈 | CAS号108-24-7 乙酸酐 | CAS号141-78-6 乙酸乙酯 | CAS号918-00-3 1,1,1-三氯丙酮 | CAS号20193-20-8 N-乙基正丙胺 | CAS号67809-15-8 N-nitroso-N-pro... | CAS号63832-65-5 N-nitro-N-propy...

📜Pentan-2-One Oxime置于三甲基乙酰氯体系中,用 二氯甲烷,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 4.0H,反应生成 N-正丙基乙酰胺
参考文献:使用新戊酰氯/ Dmf配合物对肟进行贝克曼重排
标题:使用新戊酰氯/ Dmf配合物对肟进行贝克曼重排
摘要:发现新的新戊酰氯和dmf的复合物通过贝克曼重排能以优异的转化率将酮肟转化为其相应的酰胺或内酰胺非常有效.该方法具有显着的优势,例如效率高,反应条件温和,反应时间短.
DOI:10.1016/j.Tetlet.2011.07.045

专利信息

专利号:US-2004242897-A1
优先权日:2002-07-31
标题 :Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotides and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:WO-2017082924-A1
优先权日:2015-11-13
标题 :Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE TERRENCE R JR; HYMEL DAVID
权利人:THE US SECRETARY DEPT OF HEALTH & HUMAN SERVICES
摘要:The description provides novel compounds that may serve as anticancer therapeutics. The compounds of the description bind to polo-like kinases through the polo-box domain. The peptide derivatives of the description have achieved improved efficacy in biochemical assays against Plk1. The description also provides methods of use, methods of preparation, compositions, and kits thereof. Further, the description provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.

专利号:US-2005119332-A1
优先权日:1998-03-12
标 题 :Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases)
发明人：JEPPESEN LONE; ANDERSEN HENRIK S; OLSEN OLE H; JUDGE LUKE M; HOLSWORTH DANIEL D; BAKIR FARID; AXE FRANK U; GE YU
摘要:The present invention provides novel compounds of formula 1a, n nnovel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.

专利号:US-2002165398-A1
优先权日:1998-03-12
标题:Modulators of protein tyrosine phosphatases (PTPases)
发明人：JEPPESEN LONE; ANDERSEN HENRIK SUNE; OLSEN OLE HVILSTED; JUDGE LUKE MILBURN; HOLSWORTH DANIEL DALE; BAKIR FARID; AXE FRANK URBAN; GE YU
摘要:The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. n The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimers disease and schizophrenia, and infectious diseases.

专利号:US-2012277444-A1
优先权日:2011-04-27
标 题:Synthesis of hydroxyalkyl amides from esters
发明人：MAHADEVAN SHIVKUMAR; VENKATASUBBAN KUNISI
权利人:MAHADEVAN SHIVKUMAR; VENKATASUBBAN KUNISI
摘要:Hydroxyamides are synthesized from esters. A process of making hydroxyalkyl amides comprises: reacting an ester with a hydroxyalkyl amine having the formula H 2 N—R 3 —OH wherein R 3 is a substituted or unsubstituted C2 to C5 alkyl, in the presence of a catalyst in an anhydrous solution to form the hydroxyalkyl amides. Monomers suitable for formation of polymeric articles can utilize these hydroxyamides.

专利号:US-4161609-A
优先权日:1977-09-14
标题:Synthesis of carboxylic acid esters
发明人：CRAMER RICHARD D
权利人:DU PONT
摘要:A method is provided for converting a carboxylic acid amide to a carboxylic acid ester by reacting a vaporized mixture of the amide and an aliphatic alcohol or a phenol in the presence of a suitable catalyst at temperatures of from 100 DEG C. to 400 DEG C. The process is especially useful for the conversion of methacrylamide to methyl methacrylate.