CAS: 38628-51-2; 4-(2-Carboxyethyl)Benzoic Acid

该化合物是一种二恶英酸衍生物,其成分既有芳香的,也有异丙烯酸,使它成为有机合成的多功能中间体.其双功能结构允许选择性反应,有利于聚合化学,制药和特殊材料的应用.该化合物的硬性芳香核心和柔性碳oxyl侧链有助于其设计高性能聚酯或聚酰胺单体的实用性.它也因其能形成稳定氨化或酯间联系,成为生物活性分子的前体.产品的纯度和一贯质量确保了要求高的合成工艺的可靠性能.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号19675-63-9 4-(2-羧基乙烯基)苯甲酸 | CAS号619-66-9 对醛基苯甲酸 | CAS号42287-94-5 3-(4-氰基苯基)丙酸 | CAS号1505-50-6 3-(4-甲苯)丙酸 | CAS号58420-21-6 3-(4-异丙基苯基)丙酸 | CAS号18664-39-6 4-氰基肉桂酸 | CAS号59577-61-6 (4-isopropyl-be... | CAS号122-03-2 枯名醛 | CAS号60031-08-5 1-茚酮-6-甲酸 | CAS号68634-03-7 3-氧代-2,3-二氢-1H-... | CAS号88371-24-8 2-氧代-1,2,3,4-四氢... | CAS号38628-52-3 ethyl 4-(3-etho...

合成工艺路线路线简述

    📜3-(4-甲苯)丙酸置于permanganate(Vii) Ion,Potassium Carbonate体系中,化学反应生成3-(4-羧基苯基)丙酸
    参考文献:Skraup; Schwamberger,Justus Liebigs Annalen Der Chemie,1928,Vol. 462,P. 147
    标题:Skraup; Schwamberger,Justus Liebigs Annalen Der Chemie,1928,Vol. 462,P. 147

    海关参考信息

    专利信息


    专利号:US-7125906-B2
    优先权日:2002-04-03
    标题 :Indole derivatives having anti-angiogenetic activity
    发明人:ARNOULD JEAN-CLAUDE
    权利人:ASTRAZENECA AB
    摘要:The invention relates to the use of a compound of Formula (I), for the manufacture of a medicament to inhibit and/or reverse and/or alleviate symptoms of angiogenesis and/or any disease state associated with angiogenesis: n nwherein: X, p, q, R 1 , R 2 , R 3 , R 4 , and R 5 are as defined in the description. The invention also related to use of compounds of Formula (I) as medicaments and also to novel compounds of Formula (I). The invention further provides pharmaceutical compositions of compounds of Formula (I) and processes for the synthesis of compounds of Formula (I).

    专利号:US-2011046395-A1
    优先权日:2008-01-25
    标 题 :Process for the manufacture of a 6-fluoro-1,2-dihydro-2-oxo-3h-indol-3-ylidene derivative
    发明人:RALL WERNER; PFRENGLE WALDEMAR; SCHNAUBELT JUERGEN
    权利人:BOEHRINGER INGELHEIM INT
    摘要:The present invention relates to a process for the manufacture of the compound 4-[(Z)-[[4-[(dimethylamino)methyl]phenyl]amino](6-fluoro-1,2-dihydro-2-oxo-3H-in-dol-3-ylidene)methyl]-benzenepropanoic acid and to a new intermediate for the synthesis.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1107/s1600536811013171
    摘要:Wu YP, Tang L, Fu F, Liu QR. 4-Methyl-sulfanyl-6-(4-pyrid-yl)-1,3,5-triazin-2-amine. Acta Crystallogr Sect E Struct Rep Online. 2011 May 01;67(Pt 5):o1143.
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