CAS: 2835-81-6; H-Dl-Abu-Oh

主要参考文献

参考标题:Design, Synthesis And Biological Evaluation Of Novel Quinazoline-2,4-Diones Conjugated With Different Amino Acids As Potential Chitin Synthase Inhibitors
作者:Nada A. Noureldin,Hend Kothayer,El-Sayed M. Lashine,Mohamed M. Baraka,Yanrong Huang,Bing Li,Qinggang Ji |发布日期:2018.5
摘要:Acetamido) Acids) (6 A-M), (7) Has Been Designed To Inhibit The Action Of Fungus Chitin Synthase Enzyme (Chs). The Synthesis Of The Designed Compounds Was Carried Out In Four Steps Starting From The Reaction Between 1-Methylquinazoline-2,4(1H,3H)-Dione And Ethyl Chloroacetate To Yield The Ethyl Acetate Derivative. This Ester Was Hydrolyzed To The Corresponding Carboxylic Acid Derivative That Was Then

合成参考文献

参考文献:10.1038/nature10354
摘要:Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E; CARDIoGRAM, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C. Human metabolic individuality in biomedical and pharmaceutical research. Nature. 2011 Aug 31;477(7362):54–60.