CAS: 270596-35-5; (R)-3-Amino-6-Phenylhex-5-Enoic Acid
该化合物是一种氨酸衍生物,其独特的结构包括一个苯基组和一个乙酸脊柱,该化合物的特点是第三个碳的手性中心,有助于其立体化学和潜在的生物活动;氨基酸组的存在允许其参与各种生物化学反应,使其与医药化学和生物化学领域相关;苯组强化其水恐特性,影响其溶解性和与生物膜的相互作用;此外,乙酸部分还引入不饱和性,这可能会影响化合物的再活动性和稳定性.
- 英文名称(R)-3-Amino-6-Phenylhex-5-Enoic Acid
- 中文名称(r)-3-氨基-6-苯基-5-烯酸
- IUPAC名称(R)-3-amino-6-phenylhex-5-enoic acid
- 其它别名(R)-3-Amino-(6-Phenyl)-5-Hexenoic Acid Hcl; (R)-3-Amino-(6-Phenyl)-5-Hexenoic Acid Hydrochloride; Styryl-D-Beta-Homoalanine Hydrochloride; H-D-B-Hoala(Styryl)-Oh·hcl; H-D-Beta-Hoala(Styryl)-Oh Hcl; H-D-Phe(*5,6:Ch,C*ch2)-Oh Hcl; (R)-3-Amino-(6-Phenyl)-5-Hexenoicacidcl
- CAS编号270596-35-5
- MFCD编号:MFCD01860995
- 分子式:C12H15NO2分子量:205.26
- 产品CID: 1250324
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
相似化合物
270263-08-6 1217460-65-5 332064-75-2物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902300000-甲苯
2902500000-苯乙烯 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2022243244-A1
优先权日:2019-10-10
标 题 :Compositions and methods for in vivo synthesis of unnatural polypeptides
发明人：ROMESBERG FLOYD E; FISCHER EMIL C; HASHIMOTO KOJI; FELDMAN AARON W; DIEN VIVIAN T; ZHANG YORKE
权利人:SCRIPPS RESEARCH INST
摘要:Disclosed herein are compositions, methods, and kits for a cell incorporating unnatural amino acids into an unnatural polypeptide. Also disclosed herein are compositions, methods, and kits for increasing activity and yield of the unnatural polypeptide synthesized by the cell.
专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人：GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:US-2025084410-A1
优先权日:2015-01-12
标 题:Incorporation of unnatural nucleotides and methods thereof
发明人：PTACIN JEROD; MALYSHEV DENIS A; CAFFARO CAROLINA E
权利人:SYNTHORX INC
摘要:Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
专利号:US-2018371021-A1
优先权日:2017-05-11
标 题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
专利号:WO-2021072167-A1
优先权日:2019-10-10
标 题:Compositions and methods for in vivo synthesis of unnatural polypeptides
专利号:US-11091522-B2
优先权日:2018-07-23
标题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.
