CAS: 2645-07-0; 2-(4-Nitrobenzamido)Acetic Acid

该化合物是一种硝基替代芳香化合物,其成分包括形式胺和碳酸性功能组,其结构特性使它在有机合成中成为有价值的中间体,特别是用于制备药品,农用化学品和特殊化学品.硝基乙酸组的存在增强了在电药和核生殖替代反应中的再活性,而碳箱酸混合物允许进一步衍生.该化合物经常用于浸泡混合反应和作为异环化合物的前体.其定义明确的晶体形式确保了一致性和稳定性,使之适合于需要精确化学转化的研究和工业应用.

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61-78-9 1219805-41-0 7512-77-8

上下游产品

ethyl 2-(4-nitrobenzamido)acetate 4-nitro-benzoyl chloride glycine H-oxazol-5-one2-(4-nitro-phenyl)-4H-oxazol-5-one p-Aminohippuric acid 4-nitro-N-(2-oxo-2-(phenylamino)ethyl)benzamide 2-(4-nitrophenyl)-4-(2-thienylmethylene)oxazol-5-one H-oxazol-5-one4-(2,6-dimethyl-pyran-4-ylidene)-2-(4-nitro-phenyl)-4H-oxazol-5-one

合成工艺路线路线简述

    📜2-<4-Nitrophenyl>-Oxazol-5-On置于hydroxide体系中,化学反应生成4-硝基马尿酸
    参考文献:Structure-Reactivity Studies On The Equilibrium Reaction Between Phenolate Ions And 2-Aryloxazolin-5-Ones: Data Consistent With A Concerted Acyl-Group-Transfer Mechanism
    标题:Structure-Reactivity Studies On The Equilibrium Reaction Between Phenolate Ions And 2-Aryloxazolin-5-Ones: Data Consistent With A Concerted Acyl-Group-Transfer Mechanism
    摘要:
    Doi:10.1021/ja00542A028

    海关参考信息

    专利信息


    专利号:US-9217012-B2
    优先权日:2009-04-08
    标题 :Inhibitors of protein tyrosine phosphatases
    发明人:ZHANG ZHONG-YIN; ZHANG SHENG
    权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
    摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

    专利号:CN-118439966-A
    优先权日:2024-07-05
    标 题:Synthesis method of p-nitroaniline compound

    供应商参考报价(招募中)

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

    合成参考文献


    摘要:National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.
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