CAS: 2284-31-3; 5,7-Dihydroxy-3-(3-Hydroxy-4-Methoxyphenyl)-4H-Chromen-4-One

该化合物是主要在各种植物,特别是豆类家族中发现的氟氯素化合物,其特点是多酚结构,有助于其抗氧化特性.Pratensein展示了黄色的颜色,在有机溶剂中可溶解,但水中的溶解性有限.该化合物因其潜在的健康惠益,包括防炎,抗微生物和抗癌活动,引起了人们的兴趣,这些活动主要归因于它能够挽救自由基和调节各种生物途径.此外,Pratensein在植物防病原体和草药机制中可能发挥作用.它存在于饮食来源中,表明对人类健康的潜在影响,尽管为了充分阐明其生物效应和行动机制,有必要开展进一步研究.许多氟氯素,青蒿的生物利用率和人体代谢剂都是不断调查的领域,强调需要进行更全面的研究,以了解其治疗潜力.

结构式图片

上下游产品

CAS号63240-66-4 3',4',6'-tri-O-... | CAS号70413-06-8 2,3',4,6-tetrah... | CAS号124-63-0 甲基磺酰氯

合成工艺路线路线简述

    📜红车轴草素-7-O-吡喃葡萄糖苷置于三氟乙酸体系中,化学反应 2.0H,反应生成红车轴草素
    参考文献:The First Identification Of Isoflavones From A Bryophyte
    标题:The First Identification Of Isoflavones From A Bryophyte
    摘要:
    Doi:10.1016/s0031-9422(00)82611-4

    海关参考信息

    专利信息


    专利号:US-10030003-B2
    优先权日:2014-09-10
    标 题:Synthesis of isoflavanes and intermediates thereof
    发明人:BELIAEV NIKOLAI; SHAFRAN YURI
    权利人:SYSTEM BIOLOGIE AG
    摘要:Subject of the invention is a method for enantioselective production of an isoflavane from an isoflavone, comprising the steps: (a) selectively reducing the isoflavone, such that the 4-keto group of the isoflavone is converted to a 4-hydroxy group, and the 2,3-double bond of the isoflavone is converted to a 2,3-single bond, thereby obtaining a 4-hydroxy intermediate, and (b) reacting the 4-hydroxy intermediate with a chiral reagent, such that a chiral group is covalently attached to the C4-position of the 4-hydroxy intermediate, thereby obtaining a chiral intermediate. The invention also relates to intermediates of formulae (IV), (V), (VI) and (VII) obtainable in the inventive process.

    专利号:US-8969596-B2
    优先权日:2008-08-14
    标题:Synthesis of equol
    发明人:STEFFAN BERT
    权利人:STEFFAN BERT
    摘要:Subject of the invention is a method for the production of isoflavanes from isoflavones, whereby in a first reaction step (a) the 4-keto group of the isoflavone is reduced in a enantioselective manner, whilst the 2,3-double bond is maintained, to the 4-hydroxy compound.

    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:US-2012094336-A1
    优先权日:2008-08-14
    标题:Synthesis of equol

    专利号:CA-2960437-A1
    优先权日:2014-09-10
    标 题 :Synthesis of isoflavanes and intermediates thereof

    专利号:WO-2006053688-A1
    优先权日:2004-11-17
    标 题:Cosmetic and dermatological preparations for the treatment of mature skin
    发明人:DOERING THOMAS
    权利人:HENKEL KGAA; DOERING THOMAS
    摘要:The invention relates to topical cosmetic or dermatological compositions for the treatment of mature or intrinsically or extrinsically aged skin, in particular, for anti-wrinkle treatment, containing a combination of at least two selected peptides in a suitable cosmetic or dermatological vehicle, which have an effect at differing points of the process of collagen and/or fibronectin synthesis.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Wang R, Wei Y, Deng W, Teng J. Pratensein Mitigates Oxidative Stress and NLRP3 Inflammasome Activation in OGD/R-Injured HT22 Cells by Activating Nrf2-Anti-oxidant Signaling. Neurotox Res. 2022 Apr;40(2):384-394. doi: 10.1007/s12640-022-00472-z. Epub 2022 Jan 22.
    101:208-17. doi: 10.1016/j.fitote.2015.01.017. Epub 2015 Feb 7. Erratum in: Fitoterapia. 2022 Mar;157:105123. doi: 10.1016/j.fitote.2022.105123.
    592:48-53. doi: 10.1016/j.neulet.2015.03.003. Epub 2015 Mar 4.

    合成参考文献


    参考文献:10.1007/s10886-010-9748-8
    摘要:Stevenson PC, D’Cunha RF, Grzywacz D. Inactivation of Baculovirus by Isoflavonoids on Chickpea (Cicer arietinum) Leaf Surfaces Reduces the Efficacy of Nucleopolyhedrovirus Against Helicoverpa armigera. Journal of Chemical Ecology. 2010 Feb 10;36(2):227–35. doi: 10.1007/s10886-010-9748-8.
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