CAS: 142546-15-4; Sageone
该化合物是一种化学化合物,属于被称为选择性血清素再摄入抑制剂的物质类别,主要研究该物质在治疗各种情绪紊乱,包括抑郁和焦虑方面的潜在应用,该化合物展示了一种行动机制,它涉及抑制血清素再摄入,从而增加合成骨灰裂的血清素供应,这可以提高情绪和情感健康.Sageone的特点是其特定分子结构,它有助于其药理特性.与许多SSRI一样,它可能具有一系列副作用,其效力在个人之间也各不相同.正在对其安全特征,剂量和长期影响进行研究,而且对于提供保健服务者在开药时必须考虑到这些因素.总的来说,Sageone在...
- 英文名称Sageone
- 中文名称紫苏酮
- IUPAC名称5,6-dihydroxy-7-isopropyl-1,1-dimethyl-2,3,9,10-tetrahydrophenanthren-4(1H)-one
- 其它别名Sageone; 2,3,9,10-Tetrahydro-5,6-Dihydroxy-1,1-Dimethyl-7-(1-Methylethyl)-4(1H)-Phenanthrenone; 4(1H)-Phenanthrenone, 2,3,9,10-Tetrahydro-5,6-Dihydroxy-1,1-Dimethyl-7-(1-Methylethyl)-
- CAS编号142546-15-4
- MFCD编号:MFCD21333455
- 分子式:C19H24O3分子量:300.4
- 产品CID: 650862
- 产品分类天然产物 → 萜类
物理性质
上下游产品
7-Isopropyl-5,6-dimethoxy-1,1-dimethyl-2,3,9,10-tetrahydro-1H-phenanthren-4-one合成工艺路线路线简述
- 合成目标产物 Sageone 主要起始原料 4(1H)-Phenanthrenone, 2,3,9,10-Tetrahydro-5,6-Dimethoxy-1,1-Dimethyl-7-(1-Methylethyl)-
- (文献来源)合成步骤主要原料 4(1H)-Phenanthrenone, 2,3,9,10-Tetrahydro-5,6-Dimethoxy-1,1-Dimethyl-7-(1-Methylethyl)-
📜5,6-Dimethoxy-1,1-Dimethyl-7-Propan-2-Yl-2,3,9,10-Tetrahydrophenanthren-4-One置于三溴化硼体系中,用 二氯甲烷 用作溶剂,化学反应 2.0H,以88%的收率获得紫苏酮
参考文献:Use Of Conjugated Dienones In Cyclialkylations: Total Syntheses Of Arucadiol,1,2-Didehydromiltirone,(+/-)-Hinokione,(+/-)-Nimbidiol,Sageone,And Miltirone
标题:Use Of Conjugated Dienones In Cyclialkylations: Total Syntheses Of Arucadiol,1,2-Didehydromiltirone,(+/-)-Hinokione,(+/-)-Nimbidiol,Sageone,And Miltirone
摘要:Functionalized Hydrophenanthrenes Can Be Prepared Using A Cyclialkylation-Based Strategy. These Annulations Are Highly Dependent On The Directing Effects Of The Arene Substitutents And On Conformational Considerations. The Utility Of This Methodology Was Featured In The Syntheses Of Six Diterpenoids.
Doi:10.1021/jo970570Q
海关参考信息
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合成参考文献
参考文献:10.1016/0031-9422(92)80282-j
摘要:González AG, Andrés LS, Aguiar ZE, Luis JG. Diterpenes from Salvia mellifera and their biogenetic significance. Phytochemistry. 1992 Apr;31(4):1297–305. doi: 10.1016/0031-9422(92)80282-j.
参考文献:10.1016/0031-9422(92)83493-i
摘要:Luis JG, González AG, Andrés LS, Mederos S. Diterpenes from in vitro-grown Salvia canariensis. Phytochemistry. 1992 Sep;31(9):3272–3. doi: 10.1016/0031-9422(92)83493-i.
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