CAS: 1139-30-6; (1R,4R,6R,10S)-4,12,12-Trimethyl-9-Methylene-5-Oxatricyclo[8.2.0.04,6]Dodecane

上下游产品

CAS号87-44-5 反式石竹烯 | CAS号93-59-4 过氧化氢苯甲酰 | CAS号2311-91-3 perphthalic acid | CAS号32214-91-8 乙酸石竹烯酯

📜(Z)-(1R,9S)-4,11,11-Trimethyl-8-Methylene-Bicyclo[7.2.0]Undec-3-En-5-One置于lithium Aluminium Tetrahydride,间氯过氧苯甲酸体系中,用 乙醚,氯仿 用作溶剂,化学反应 8.0H,反应生成丁香酚杂质c(Ep)
参考文献:来自红海的三只软珊瑚的八种新的xenia二萜
标题:来自红海的三只软珊瑚的八种新的xenia二萜
摘要:对来自埃拉特湾(红海),Xenia Macrospiculata,X.Obscuronata和x. Lilielae的三种软珊瑚的萜类成分含量进行了分离,结果分离出了8种新的二萜.其中的两种新化合物属于xeniolides(xenialactol-D(10A)和xeniolide-E(1))以及其他六种(4,14-Dipoxyxeniaphyllene(15),4,5-环氧木叶素-14,15-二醇(17),4,14-二环氧-木叶素-A (21A),Xeniaphyllenol-B(23A),Xeniaphyllenolol-C(24A)和xeniaphyllantriol(25))是新的木乃伊花(异戊二烯化石竹花).各种化合物的结构确定均基于化学转化以及1 H和13 C NMR光谱.已经合成了几种已知的石竹烯衍生物,用于13 C NMR光谱和化学比较.的13 C NMR已被证明是用于结构和立体化学的确定优异的探针.
Doi:10.1016/s0040-4020(01)91590-X

专利信息

专利号:US-2024240209-A1
优先权日:2021-04-20
标 题:Synthesis of enantiopure cis-a-irone from a renewable carbon source
发明人：CHEN XIXIAN; ZHANG CONGQIANG; T REHKA; SHUKAL SUDHA; SMITH DEREK; ANDRÉ ISABELLE; JEREMY ESQUE
权利人:AGENCY SCIENCE TECH & RES; INSTITUT NATIONAL DE RECH POUR L AGRICULTURE LALIMENTATION ET LENVIRONMENT; CENTRE NAT RECH SCIENT; INSTITUT NAT DES SCIENCES APPLIQUEES DE TOULOUSE
摘要:Synthesis of enantiopure cis-α-irone from a renewable carbon source Disclosed herein are natural and synthetic enzymes capable of performing a method of producing cis-α-irone. The method comprises providing an enzyme capable of converting psi-ionone to cis-α-irone; and contacting the enzyme and psi-ionone under suitable conditions to produce cis-α-irone. The enzyme may be a methyltransferase from Streptomyces albireticuli (SaMT), a promiscuous bifunctional methyltransferase/cyclase (pMT1) enzyme from Streptomyces, or a modified pMT1 enzyme with at least one substitution. The enzymes allow the in-vivo and in-vitro production of cis-α-irone including the use of glucose as feedstock for the biotransformation into cis-α-irone.

专利号:US-2002165207-A1
优先权日:2001-05-02
标题 :Compositions and methods for the treatment of diabetic neuropathy
发明人：ROSENBLOOM RICHARD
摘要:Compositions and a method for the treatment of diabetic neuropathy is disclosed. The compositions comprise a mixture of a compound that promotes synthesis of nerve growth factor, an aldose reductase inhibitor and an antioxidant, optionally formulated in a pharmaceutically acceptable carrier. This combination of active agents provides significant, effective relief of the symptoms of diabetic neuropathy, as well as at least partial recovery of lost neurological function in some cases. In addition, the compositions of the present invention, when used in effective amounts to treat diabetic neuropathy, do not exhibit the severe side effects of many prior art compositions proposed for treatment of this ailment. n In a second aspect, a method for the administration of a composition in accordance with the present invention for the treatment of diabetic neuropathy is disclosed. In the method, an effective amount of the composition of the invention is administered on a regular basis over a period of time sufficient to provide the beneficial effects of relief from the symptoms of diabetic neuropathy, as well as at least some recovery of the damaged nerve tissues.

专利号:US-8759632-B2
优先权日:2005-07-05
标 题 :Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
发明人：RO DAE-KYUN; NEWMAN KARYN; PARADISE ERIC M; KEASLING JAY D; OUELLET MARIO; EACHUS RACHEL; HO KIMBERLY; HAM TIMOTHY
权利人:RO DAE-KYUN; NEWMAN KARYN; PARADISE ERIC M; KEASLING JAY D; OUELLET MARIO; EACHUS RACHEL; HO KIMBERLY; HAM TIMOTHY; UNIV CALIFORNIA
摘要:The present invention provides isolated nucleic acids comprising nucleotide sequences encoding isoprenoid modifying enzymes, as well as recombinant vectors comprising the nucleic acids. The present invention further provides genetically modified host cells comprising a subject nucleic acid or recombinant vector. The present invention further provides a transgenic plant comprising a subject nucleic acid. The present invention further provides methods of producing an isoprenoid compound, the method generally involving culturing a subject genetically modified host cell under conditions that permit synthesis of an isoprenoid compound modifying enzyme encoded by a subject nucleic acid.

专利号:US-7232844-B2
优先权日:2002-03-20
标 题:Insect repellent compounds
发明人：HALLAHAN DAVID L
权利人:DU PONT
摘要:Dihydronepetalactone, a minor natural constituent of the essential oil of catmints (Nepeta spp.) such as Nepeta cataria, has been identified as an effective insect repellent compound. Synthesis of dihydronepetalactone may be achieved by hydrogenation of nepetalactone, the major constituent of catmint essential oils. This compound, which also has fragrance properties, may be used commercially for its insect repellent properties.

专利号:US-10906033-B2
优先权日:2016-03-28
标题 :Synthesis and application of chiral substituted polyvinylpyrrolidinones
发明人：HUA DUY H
权利人:UNIV KANSAS STATE
摘要:Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.

专利号:US-7927794-B2
优先权日:2003-09-29
标题 :Methods for identifying a biosynthetic pathway gene product
发明人：KEASLING JAY D; NEWMAN JACK D; PITERA DOUGLAS J; WITHERS III SYDNOR T; REILING KEITH KINKEAD; MARTIN VINCENT J J
权利人:UNIV CALIFORNIA
摘要:The present invention provides isolated, genetically modified host cells, where a host cell is genetically modified with a nucleic acid that includes a nucleotide sequence encoding a biosynthetic pathway enzyme. Synthesis of the enzyme in the host cell results in conversion of a substrate for the enzyme into a biosynthetic pathway intermediate, which intermediate is produced in an amount effective to inhibit growth of the genetically modified host cell. The present invention further provides compositions and kits comprising a subject genetically modified host cell. Subject host cells are useful for identifying a gene product having activity in a biosynthetic pathway. The present invention further provides methods of identifying a gene product having activity in a biosynthetic pathway.