CAS: 941296-80-6; (S)-2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)(Methyl)Amino)-4-Oxo-4-(Tritylamino)Butanoic Acid

• 英文名称(S)-2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)(Methyl)Amino)-4-Oxo-4-(Tritylamino)Butanoic Acid
• 中文名称Fmoc-N-甲基-N'-三苯甲基-L-天冬氨酰胺
• IUPAC名称N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N2-methyl-N4-trityl-L-asparagine
• 其它别名N-α-Fmoc-N-α-Methyl-N-β-Trityl-L-Asparagine
• CAS编号941296-80-6
• MFCD编号:MFCD22200773
• 分子式:C39H34N2O5
• 分子量:610.7
• 产品CID: 1988118
• 产品分类有机原料→生命科学→氨基酸及其衍生物→天冬酰胺及其衍生物

• 相似结构搜索
• InChIKey: YZBDIRBPZCFMAZ-DHUJRADRSA-N
• YZBDIRBPZCFMAZ-BSICABFTNA-N…
• 计算化学: 氢键受体数4.0氢键供体数2.0可旋转键数10.0

相似化合物

物理性质

• 沸点836.3±65.0 °C at 760 mmHg
• 密度1.260±0.06 g/cm3(预测)
• pKa:3.81±0.10(预测)
• PSA:95.94
• LogP:6.8189
• 外观形态白色至类白色固体
• 储存条件储存在 -15°C to -25°C.
• 产品应用该化合物用于中间药剂.

MSDS等安全信息

• GHS符号GHS07
• 警示词Warning
• 危险描述H302-H315-H319-H335
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
• WGK GermanyWGK 3 highly water endangering

合成工艺路线路线简述

• 28920-43-6 = 941296-80-6
  反应条件:1.1 Reagents: Sodium Thiophenolate Solvents: Dimethylformamide; 3 H,Rt1.2 Reagents: Potassium Bisulfate Solvents: Water; Ph 3 - 41.3 Reagents: Sodium Carbonate Solvents: Water; Ph 91.4 3 H,0 °C1.5 Reagents: Potassium Bisulfate Solvents: Water; Ph 3 - 4
  标题:An Efficient Preparation Of N-Methyl-α-Amino Acids From N-Nosyl-α-Amino Acid Phenacyl Esters
  作者:Leggio,Antonella; Belsito,Emilia Lucia; De Marco,Rosaria; Liguori,Angelo; Perri,Francesca; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2010 卷标:75(5) 页码:1386-1392]
  
  28920-43-6 + 941296-84-0 = 941296-80-6
  反应条件:1.1 Reagents: Diisopropylethylamine Solvents: Dimethylformamide,Dichloromethane; 2 H,Rt1.2 Reagents: Methanol,Diisopropylethylamine Solvents: Dichloromethane; 10 Min,Rt1.3 Solvents: Dichloromethane; 4 H,Rt1.4 Reagents: Thiophenol,Potassium Carbonate Solvents: Dimethylformamide; 10 Min,Rt1.5 Solvents: Dimethylformamide; 2 H,Rt1.6 Reagents: Diisopropylethylamine Solvents: Dichloromethane; 2 H,Rt1.7 Reagents: Acetic Acid,2,2,2-Trifluoroethanol Solvents: Dichloromethane; 2 H,Rt
  标题:Solid-Phase Synthesis Of N-Nosyl- And N-Fmoc-N-Methyl-α-Amino Acids
  作者:Di Gioia,Maria Luisa; Leggio,Antonella; Liguori,Angelo; Perri,Francesca
  参考文献:Journal Of Organic Chemistry 日期:2007 卷标:72(10) 页码:3723-3728

海关参考信息

• 2902600000-乙苯
  2905121000-正丙醇
  2905130000-正丁醇
  2912110000-甲醛
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管