CAS: 90509-02-7; Luxabendazole

上下游产品

5-羟基-2-苯并咪唑氨基甲酸甲酯 (5-Hydroxy-1(3)H-Benzoimidazol-2-yl)-Carbamic Acid Methyl Ester 22769-68-2

1,2-Diamino-4-(4-Fluorophenylsulfonyloxy)Benzene,1,3-二羧甲基-2-甲基-2-硫代异脲 反应生成 5-羟基-2-苯并咪唑氨基甲酸甲酯对氟苯磺酰酯
参考文献:Roesner,M.;Loewe,H.;Duewel,D.;Kirsch,R.
标题:Roesner,M.;Loewe,H.;Duewel,D.;Kirsch,R.

专利信息

专利号:US-7893271-B2
优先权日:2005-07-28
标 题 :Benzimidazole carbamates and (thio) carbamates, and the synthesis and use thereof
发明人：CHASSAING CHRISTOPHE PIERRE ALAIN
权利人:INTERVET INT BV
摘要:This invention relates to benzimidazole carbamates and (thio)carbamates corresponding to Formula I: n nHere, X 1 and X 2 are independently O or S, wherein at least one of X 1 and X 2 is O; Y 1 and Y 2 are independently O or S, wherein at least one of Y 1 and Y 2 is O; R 1 is alkyl having from 1-4 carbon atoms; R 2 , R 3 , and R 4 are independently hydrogen or a cation; R 5 and R 6 are independently hydrogen, halogen, alkyl (having from 1-8 carbon atoms), —OR 7 , —SR 8 , —CO—R 9 , —OSO 2 —Ar, or —S(O)R 10 ; R 7 is alkyl having from 1-8 carbon atoms; R 8 is alkyl (having from 1-8 carbon atoms) or aryl; R 9 is alkyl (having from 1-8 carbon atoms), cycloalkyl (having from 3-6 carbon atoms), or aryl; Ar is aryl; and R 10 is alkyl (having from 1-8 carbon atoms) or aryl. The compounds generally are soluble and stable in water, and have antiparasitic (particularly anthelmintic) activity in vivo that is comparable to known water-insoluble benzimidazole carbamates (e.g., albendazole and fenbendazole).

专利号:ES-2344275-T3
优先权日:2005-07-28
标 题 :NEW (UNCLE) CARBAMATES FROM BENZIMIDAZOL WITH ANTIPARASITARY ACTIVITY AND SYNTHESIS OF THEM.

专利号:PT-1913009-E
优先权日:2005-07-28
标 题 :NEW (TIO) CARBAMATES OF BENZIMIDAZOLE WITH ANTIPARASITARY ACTIVITY AND ITS SYNTHESIS