CAS: 83792-48-7; Fmoc-Ser(Bzl)-Oh

相似化合物

122889-11-6 10433-52-0 116861-26-8

上下游产品

benzyl alcohol-3-(9-fluorenylmethyloxycarbonyl)-5-oxooxazolidine(4S)-4-(benzyloxy)methyl-3-(9-fluorenylmethyloxycarbonyl)-5-oxooxazolidine 2C6H5)-ODpmFm°C-L-Ser(°CH2C6H5)-ODpm α-(fluorenylmethoxycarbonyl)-O-(benzyl)serylleucine t-butyl esterNα-(fluorenylmethoxycarbonyl)-O-(benzyl)serylleucine t-butyl ester Fm°C-Ser(Bzl) anhydride

4-Tert-Butyl 3-(9H-Fluoren-9-yl)Methyl (4S)-2,2-Dioxo-1,2Lambda6,3-Oxathiazolidine-3,4-Dicarboxylate,苯甲醇置于sodium Dihydrogenphosphate体系中,化学反应 2.0H,以39.5%的收率获得产物fmoc-O-苄基-L-丝氨酸
参考文献:O-Substituted Serine Derivative Production Method
标题:O-Substituted Serine Derivative Production Method
摘要:发现通过将氨基酸衍生物与环化试剂反应可以反应生成环状磺胺酸酯.此外,还发现通过将环状磺胺酸酯与醇反应可以产生o-取代的丝氨酸衍生物.

专利信息

专利号:US-12251674-B2
优先权日:2012-11-14
标 题:Substrates, systems, and methods for array synthesis and biomolecular analysis
发明人：RAJASEKARAN JOHN J; JAYARAMAN VASANTH; WANG TIANHAO; BEI KANG; KRISHNAMURTHY HARI KRISHNAN; VEDANTHAM PUNITHA
权利人:VIBRANT HOLDINGS LLC
摘要:Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N→C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.

专利号:US-6180767-B1
优先权日:1996-01-11
标 题 :Peptide nucleic acid conjugates
发明人：WICKSTROM ERIC; BASU SOUMITRA
权利人:UNIV JEFFERSON
摘要:Peptide nucleic acid (PNA) oligomers are conjugated to a ligand which is capable of binding to a cell surface receptor. The ligand facilitates cellular uptake of the PNA oligomer. Where the ligand is a peptide, the conjugate may be produced as a unitary molecule by first synthesizing the peptide ligand by solid phase or solution peptide synthesis, followed by synthesis of the PNA oligomer as an extension of the peptide ligand. The PNA oligomer base sequence is selected to hybridize to a target polynucleotide sequence by either triplex (dsDNA) or duplex (ssDNA; RNA) formation.

专利号:US-6482921-B1
优先权日:1999-01-28
标题:Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use
发明人：BOOJAMRA CONSTANTINE G; LEMOINE REMY C; HECKER SCOTT; LEE VING J; LEGER ROGER
权利人:ESSENTIAL THERAPEUTICS INC
摘要:The present invention relates to dihydro derivatives of the uridyl peptide antibiotics mureidomycin, pacidimycin and napsamycin which have antibiotic activity against a number of bacterial strains including strains resistant to current therapeutic antibiotics.

专利号:CN-102180964-A
优先权日:2011-03-16
标题:A kind of solid-phase synthesis method of human relaxin-2 Relaxin

专利号:CN-102180964-B
优先权日:2011-03-16
标 题:Solid-phase synthesis method of human relaxin-2