79-63-0 = 79-62-9 反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Ethyl Acetate; 6 H,45 Psi,Rt 标题:Synthesis And Antimicrobial Activity Of Novel Oxysterols From Lanosterol 作者:Shingate,Bapurao B.; Hazra,Braja G.; Salunke,Deepak B.; Pore,Vandana S.; Shirazi,Fazal; Et Al 参考文献:Tetrahedron 日期:2013 卷标:69(52) 页码:11155-11163]
= 79-62-9 反应条件:1.1 Reagents: Hydrazine,Potassium Hydroxide Solvents: Diethylene Glycol1.2 Solvents: Dichloromethane 标题:Synthesis Of 15α-Fluoro-24,25-Dihydrolanosterol As A Potential Inhibitor And/or Mechanistic Probe For Lanosterol 14α-Demethylase 作者:Morisaki,Masuo; Igata,Tomoko; Yamamoto,Satomi 参考文献:Chemical & Pharmaceutical Bulletin 日期:2000 卷标:48(10) 页码:1474-1479]
79-63-0 = 79-62-9 反应条件:1.1 Reagents: Hydrogen Catalysts: Platinum Dioxide,Platinum Solvents: Acetic Acid; 17 H,Heated 标题:Allylic Oxidation Of Steroidal Olefins By Vanadyl Acetylacetonate And Tert-Butyl Hydroperoxide 作者:Grainger,Wendell S.; Parish,Edward J. 参考文献:Steroids 日期:2015 卷标:101 页码:103-109]
79-63-0 = 79-62-9 反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Dichloromethane; 24 H,50 Pa,Rt 标题:Spin Equilibrium And O2-Binding Kinetics Of Mycobacterium Tuberculosis Cyp51 With Mutations In The Histidine-Threonine Dyad 作者:Jennings,Gareth K.; Modi,Anuja; Elenewski,Justin E.; Ritchie,Caroline M.; Nguyen,Thuy; Et Al 参考文献:Journal Of Inorganic Biochemistry 日期:2014 卷标:136 页码:81-91]
79-63-0 = 79-62-9 反应条件:1.1 Reagents: Ammonium Formate Catalysts: Palladium Solvents: Methanol; 7 H,Reflux 标题:Ammonium Formate/palladium On Carbon: A Versatile System For Catalytic Hydrogen Transfer Reductions Of Carbon-Carbon Double Bonds 作者:Paryzek,Zdzislaw; Koenig,Hanna; Tabaczka,Bartlomiej 参考文献:Synthesis 日期:2003 卷标:(13) 页码:2023-2026]
2644-75-9 = 79-62-9 反应条件:1.1 Reagents: Ethylamine,Isopropylamine,Lithium Solvents: Ethanol 标题:First Demonstration Of A Carbocation-Olefin Cyclization Route To The Lanosterol Series 作者:Corey,E. J.; Lee,Jaemoon; Liu,David R. 参考文献:Tetrahedron Letters 日期:1994 卷标:35(49) 页码:9149-52]
79-63-0 = 79-62-9 反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Benzene,Ethyl Acetate; Overnight,Rt 标题:Iridium(Iii)-Catalyzed Direct Arylation Of C-H Bonds With Diaryliodonium Salts 作者:Gao,Pan; Guo,Wei; Xue,Jingjing; Zhao,Yue; Yuan,Yu; Et Al 参考文献:Journal Of The American Chemical Society 日期:2015 卷标:137(38) 页码:12231-12240
📜Cholesterol 反应生成 二氢羊毛固醇 参考文献:Woodward Et Al.,Journal Of The Chemical Society,1957,P. 1131,1141 标题:Woodward Et Al.,Journal Of The Chemical Society,1957,P. 1131,1141
专利号:US-6726911-B1 优先权日:1999-03-09 标 题 :Biologically active compounds of Ganoderma pfeifferi DSM 13239 发明人:JUELICH WOLF; LINDEQUIST ULRIKE; JANSEN ROLF; MOTHANA RAMZI 权利人:GANOMYCIN 摘要:The present invention relates to novel biologically active compounds from fungi of the species Ganoderma pfeifferi DSM 13239, processes for their preparation, and their use. From the fruit body and mycelium of the species Ganoderma pfeifferi DSM 13239, extracts can be obtained which have antimicrobial activity and are suitable as preserving agents, for pharmaceutical and cosmetic preparations, for controlling infections, and for use in fish breeding. Antimicrobially active substances called ganomycins having activity against multiresistant germs are isolated from the extracts. The total synthesis of the ganomycins and their derivatization enables their use an antibiotics.
专利号:US-9650407-B2 优先权日:2011-11-02 标 题 :Reprogramming of cellular adhesion 发明人:GARTNER ZEV JORDAN; SELDEN NICHOLAS SCOTT; TODHUNTER MICHAEL E; LIANG SAMANTHA ISABEL; WEBER ROBERT JOSEPH; JEE NOEL YOUNGHO; LIU JENNIFER S 权利人:UNIV CALIFORNIA 摘要:Disclosed are membrane-anchored polynucleotides, and compositions comprising the membrane-anchored polynucleotides. Also disclosed are the processes for the synthesis of these compounds, compositions comprising such compounds, and the use of such compounds and compositions in research and therapeutic applications.
专利号:WO-02051393-A2 优先权日:2000-12-22 标题:Process to increase the concentration of meiosis-activating sterols (mas) in the cholesterol synthesis and the use of potent inhibitors in the process 发明人:LINDENTHAL BERNHARD 权利人:SCHERING AG; NOVO NORDISK AS; LINDENTHAL BERNHARD 摘要:The invention relates to a process to increase the concentration of meiosis-activating sterols (MAS) in the cholesterol synthesis wherein potent inhibitors where added, the use of potent inhibitors in the cholesterol synthesis, a pharmaceutical composition comprising the potent inhibitors and the use of the inhibitors for the microbiology production of meiosis-activating sterols (MAS). In the process of the invention the Δ24-reduction or/and 4α-demethylation in the cholesterol synthesis are inhibited. As a result of this inhibition the concentration of FF-MAS and/or T-MAS as meiosis-activating sterols (MAS) are increased.
专利号:US-2005038301-A1 优先权日:2001-11-08 标题 :Chemical synthesis 发明人:KAVTARADZE LEVAN KITA; MANLEY-HARRIS MERILYN 摘要:The present invention relates to a method of producing vicinal diols from a compound, the method characterised by the step of reacting the compound with a moderately strong acid in the presence one or more reagents capable of supplying hydroxyl groups wherein the moderately strong acid is a strongly reducing agent, but has a conjugate base that is a weak nucleophile. In preferred embodiments the moderately strong acid is hypophosphorous acid and the reagent(s) capable of supplying hydroxyl groups is 2-propanol in water, where 2-propanol is water soluable and organic. This method is particularly applicable to the production of vicinal diols of steroids, including lanosterol. Once vicinal diols of lanosterol diols are formed they are then capable of being further reacted to produce high purity lanosterol.
专利号:US-8647875-B2 优先权日:2004-10-15 标题 :Enzymes involved in triterpene synthesis 发明人:OSBOURN ANNE; QI XIAOQUAN 权利人:OSBOURN ANNE; QI XIAOQUAN; PLANT BIOSCIENCES LTD 摘要:This invention relates to isolated polynucleotides encoding a CYP51H. The invention also relates to the construction of recombinant DNA constructs comprising all or a portion of the isolated polynucleotide of the invention, in sense or antisense orientation, operably linked to at least one regulatory sequence.
专利号:JP-H0789943-B2 优先权日:1986-08-27 标 题:Synthesis of fatty acid ester
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合成参考文献
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