CAS: 6191-99-7; 3-Ethoxyacryloyl Chloride

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CAS号6191-97-5 3,3-二乙氧基丙酸 | CAS号6192-01-4 3-乙氧基丙烯酸 | CAS号79-37-8 草酰氯 | CAS号109-92-2 乙烯基乙醚 | CAS号75-44-5 光气 | CAS号124-38-9 二氧化碳 | CAS号5941-55-9 3-乙氧基丙烯酸乙酯 | CAS号10601-80-6 3,3-二乙氧基丙酸乙酯 | CAS号59938-07-7 (E)-1,1,1-三氯-4-... | CAS号144874-96-4 (E)-4-ethoxy-2-... | CAS号327058-51-5 (2E)-N-(4-溴苯基)-... | CAS号487-06-9 柠檬油素 | CAS号23980-99-6 N-(3-氯苯基)-3-乙氧基丙烯酰胺 | CAS号863127-76-8 (E)-N-(2-氯-6-甲基... | CAS号5941-55-9 3-乙氧基丙烯酸乙酯 | CAS号615-77-0 1-甲基尿嘧啶 | CAS号6192-01-4 3-乙氧基丙烯酸 | CAS号88371-31-7 methyl 3-(3-eth... | CAS号62102-27-6 3-ethoxy-N-[[3-... | CAS号62102-30-1 2-Propenamide,3...

3,3-二乙氧基丙酸置于氯化亚砜体系中,化学反应 1.0H,反应生成 (E)-3-乙氧基丙烯酰氯
参考文献:Anthelmintic Compounds And Compositions And Method Of Using Thereof
标题:Anthelmintic Compounds And Compositions And Method Of Using Thereof
摘要:本发明涉及以下式(i)的新型驱虫化合物: 其中 Y和z分别是双环碳环或双环杂环基团,或者y或z中的一个是双环碳环或双环杂环基团,另一个是烷基,烯基,炔基,环烷基,苯基,杂环基或杂芳基,以及变量x 1,X 2,X 3,X 4,X 5,X 6,X 7 和x 8 如本文所定义.本发明还提供了包含本发明的驱虫化合物的兽药组合物,以及它们用于治疗和预防动物寄生虫感染的用途.

专利信息

专利号:US-11325912-B2
优先权日:2019-05-09
标题 :Regio-selective synthesis of imidazo[1,2-a]pyrimidines
发明人：CLAGG KYLE BRADLEY PASCUAL; WHITE NICHOLAS ANDREW; ZHANG HAIMING; GOSSELIN FRANCIS; NACK WILLIAM; O'SHEA PAUL D
权利人:GENENTECH INC
摘要:A method of regio-selectively synthesizing an imidazo-pyrimidine compound of formulae (XXa) or (XXb)comprising a step of coupling a first compound of formula XX-P1a or XX-P1b with a second compound of formula XX-P2This annulation reaction between β-ethoxy acrylamides and phosphorylated aminoimidazoles to furnish imidazo[1,2-a]pyrimidin-amines relies on steering effects from endocyclic and exocyclic phosphorylated aminoimidazoles. The reaction furnishes either 2-amino or 4-amino constitutional isomers of imidazo[1,2-a]pyrimidines with good yields and ranges of 90:10-99:1 regio-selectivity. The reaction is useful in the synthesis of various tracer molecules used in the study of neurological conditions such as where R3 and R4 together with the imidazole ring atoms to which they are bonded form a phenyl ring and the products are substituted benzimidazopyrimidines. The reaction can be generalized to form imidazo[1,2-a]pyrimidines substituted at either of their 2- and 4-positions by alkoxy or thioalkyl groups.

专利号:US-9115124-B1
优先权日:2014-03-11
标题 :Process and intermediates for the preparation of dasatinib
发明人：BARUTO ALESSANDRO; GABOARDI MAURO; CASTALDI MARTA; CASTALDI GRAZIANO
权利人:CERBIOS PHARMA SA
摘要:The present invention relates to a process for the synthesis of dasatinib and to intermediates useful for its preparation.

专利号:WO-2020227575-A1
优先权日:2019-05-09
标题 :Synthesis of labeled imidazo[1,2-a]pyrimidines

专利号:TW-202235420-A
优先权日:2019-05-09
标 题 :Synthesis of labeled imidazo[1,2-a]pyrimidines

专利号:EP-3966215-A1
优先权日:2019-05-09
标题 :Synthesis of labeled imidazo[1,2-a]pyrimidines

专利号:CN-114026092-B
优先权日:2019-05-09
标 题:Synthesis of Labeled Imidazolo[1,2-a]pyrimidine