CAS: 512-15-2; Cyclopentolate

该化合物是一种合成抗胆碱基剂,主要用作眼科应用中的细亚和百科全书剂.其主要优势在于其快速行动,通常在30分钟内诱导学生发烧,其效果与阿托品等其他物剂相比相对较短. 环球菌在肌肉乙酰胆碱酯酶受体中扮演竞争对抗者的角色,有效地阻止了硅质肌肉,并放松了螺旋藻的立体.这使得它对于视网膜镜和基金检查等诊断程序特别有用.它的中度持续时间(6至24小时)在确保足够时间进行临床评估的同时尽量减少病人的不适状态.该化合物通常被设计为盐酸盐,以便在水溶液中增强溶解性和稳定性.

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CAS号4584-46-7 二甲氨基氯乙烷盐酸

合成工艺路线路线简述

    📜环戊酮置于potassium Carbonate,Lithium Diisopropyl Amide体系中,用 四氢呋喃,乙酸乙酯 作为反应溶剂,化学反应 12.5H,反应生成 环喷托酯
    参考文献:一种盐酸环喷托酯的制备方法
    标题:一种盐酸环喷托酯的制备方法
    摘要:本发明涉及一种m型胆碱受体阻断剂盐酸环喷托酯的制备方法,包括以下步骤:以苯乙酸为起始原料,经与环戊酮反应,反应生成2‑(1‑羟基环戊基)‑苯乙酸(中间体3);后经取代,成盐反应,得到盐酸环喷托酯.该方法操作简单,安全可控,劳动保护低,适合工业化生产.

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    专利信息


    专利号:US-9650407-B2
    优先权日:2011-11-02
    标 题 :Reprogramming of cellular adhesion
    发明人:GARTNER ZEV JORDAN; SELDEN NICHOLAS SCOTT; TODHUNTER MICHAEL E; LIANG SAMANTHA ISABEL; WEBER ROBERT JOSEPH; JEE NOEL YOUNGHO; LIU JENNIFER S
    权利人:UNIV CALIFORNIA
    摘要:Disclosed are membrane-anchored polynucleotides, and compositions comprising the membrane-anchored polynucleotides. Also disclosed are the processes for the synthesis of these compounds, compositions comprising such compounds, and the use of such compounds and compositions in research and therapeutic applications.

    专利号:US-2023271983-A1
    优先权日:2020-07-29
    标题 :Functionalized isonitriles and products, preparation and uses thereof
    发明人:SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
    权利人:UNIV SANTIAGO COMPOSTELA
    摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.

    专利号:US-2007148246-A1
    优先权日:2005-08-11
    标题:Nucleic Acid-Based Matrixes
    发明人:LUO DAN; LI YOUGEN
    权利人:LUO DAN; LI YOUGEN
    摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include delivery of biologically active agents, cell and tissue culture, and cell-free protein synthesis.

    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

    专利号:US-8486621-B2
    优先权日:2005-08-11
    标题 :Nucleic acid-based matrixes
    发明人:LUO DAN; UM SOONG HO
    权利人:LUO DAN; UM SOONG HO; CORNELL RES FOUNDATION INC
    摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include cell-free protein synthesis.

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    合成参考文献


    摘要:Ma J, Kabiel M, Tucker BA, Ge J, Young MJ. Combining chondroitinase ABC and growth factors promotes the integration of murine retinal progenitor cells transplanted into Rho(-/-) mice. Mol Vis. 2011;17():1759–70.
    参考文献:10.2165/11539460-000000000-00000
    摘要:Iskedjian M, Covert DW, Walker JH. Persistence with prostaglandin agonist use with and without adjunctive therapy for glaucoma patients: a Canadian population-based analysis. Patient. 2011;4(2):133–41. doi: 10.2165/11539460-000000000-00000.
    参考文献:10.1097/adm.0b013e3181dd4f90
    摘要:Darcin AE, Dilbaz N, Yilmaz S, Cetin MK. Cyclopentolate hydrochloride eye drops addiction: a case report. J Addict Med. 2011 Mar;5(1):84–5. doi: 10.1097/adm.0b013e3181dd4f90.
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