CAS: 478-84-2; 2-Bromo-Lysergide

该化合物是属于乙醇家族的合成化合物,其特征为来自淋病酸的四环结构,该化合物的特点是2位置的溴原子和一个碳酸酯功能组,这对其独特的化学特性有帮助;乙基基基质上的特定位置上存在二乙基组和一个甲基组,影响其药理活动和溶性;乙基衍生物因其与各种...

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2-Bromolysergic Acid
麦角乙二胺 Lysergide 50-37-3

合成工艺路线路线简述

    📜麦角乙二胺 反应生成 2-溴麦角酸二乙基酰胺
    参考文献:麦角酸环系统上的取代基.三,卤化.45.关于麦角生物碱的交流
    标题:麦角酸环系统上的取代基.三,卤化.45.关于麦角生物碱的交流
    摘要:描述了麦角酸和二氢麦角酸系列的2-卤素衍生物的生产和性质.
    DOI:10.1002/hlca.19570400716

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    专利号:US-12331051-B2
    优先权日:2021-09-20
    标 题 :LSD derivatives, synthesis and method for treatment of diseases and disorders
    发明人:SHESHBARADARAN HOOSHMAND; RUDGE SCOTT; GHAFFARI ABDI; SODERMAN STEFAN; DUSPARA PETAR
    权利人:BETTERLIFE PHARMA INC
    摘要:LSD derivative compounds and polymorphs thereof, methods for their synthesis, compositions and treatment of diseases and disorders are described herein, the compounds having the structure of Formula I: n nincluding pharmaceutically acceptable salts, hydrates, solvates, tautomers, enantiomers, diastereomers, racemates, polymorphs or combinations thereof; wherein: R 1 to R 14 are each independently selected from H, or a substituted or unsubstituted hydrocarbon group and X is selected from a halo group.

    专利号:US-2023357243-A1
    优先权日:2021-09-20
    标题 :Lsd derivatives, synthesis & method for treatment of diseases and disorders

    专利号:WO-2023039682-A1
    优先权日:2021-09-20
    标题 :Lsd derivatives, synthesis & method for treatment of diseases and disorders

    专利号:EP-4405355-A1
    优先权日:2021-09-20
    标题 :Lsd derivatives, synthesis & method for treatment of diseases and disorders

    专利号:US-2023219955-A1
    优先权日:2021-09-20
    标题 :Lsd derivatives, synthesis & method for treatment of diseases and disorders

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    合成参考文献


    摘要:Psychopharmacologia, 1(20), 1959 []
    摘要:National Technical Information Service., AD277-689
    摘要:Annals of the New York Academy of Sciences., 66(668), 1957 []
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