CAS: 38444-93-8; 2,2',3,3'-Tetrachlorobiphenyl
该化合物是一种氯化联苯化合物,其特点是其2,2',3,3'和3'位置的氯原子具体替代模式,这种配置具有独特的化学稳定性和降解阻力,使其在专门研究应用中,包括在环境研究和分析化学中有用,其明确界定的结构有助于在色谱分析中精确校准,并成为多氯联苯(PCB)检测的参照标准.由于这种结构的持久性和反应性较低,它还用于环境矩阵中多氯联苯行为的调查.由于它潜在的毒性和环境影响,适当处理是必不可少的.
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: VTLYHLREPCPDKX-UHFFFAOYSA-N
- 1S/C12H6Cl4/c13-9-5-1-3-7(11(9)15)8-4-2-6-10(14)12(8)16/h1-6H
- 计算化学: 氢键受体数*氢键供体数*可旋转键数1.0
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS08 & GHS09;
注释: Health hazard & Environment - 危险类别特定目标器官毒性-重复接触 类别2
水生急性毒性 类别1
水生慢性毒性 类别1 - 警示词Warning(警告)
- 危险描述H373 |长期或反复接触可能损害器官.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响. - 防范说明P273-P391-P501-P260-P314-P501
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
欧盟法规
C&L通报上下游产品
2,3-dichloroaniline 1,2-dichloro-benzene 1,2-Dichloro-3-iodobenzene 1,2,8,9-Tetrachlorodibenzofuran合成工艺路线路线简述
- 合成目标产物 2,2',3,3'-Tetrachlorobiphenyl 主要起始原料 1,2-Dichloro-3-Iodobenzene
- (文献来源)合成步骤主要原料 1,2-Dichloro-3-Iodobenzene
📜2,3-二氯碘苯 以63%的收率获得2,2',3,3'-四氯联苯
参考文献:Gross,Ulrich; Kaufmann,Dieter,Chemische Berichte,1987,Vol. 120,P. 991-994
标题:Gross,Ulrich; Kaufmann,Dieter,Chemische Berichte,1987,Vol. 120,P. 991-994
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5243032-A
优先权日:1989-06-22
标题:Preparation of azo pigments with low pcb content by coupling in the presence of olefins
发明人：RIEPER WOLFGANG
权利人:HOECHST AG
摘要:The production which is customary in practice of monoazo compounds based on dichloro- and trichloroanilines or disazo compounds of the chlorinated biphenyl series by conventional coupling methods meets with difficulties in that the resulting pigments are contaminated by traces of polychlorinated biphenyls. n According to the invention, it has now been found that by addition of water-soluble olefins of the type ##STR1## (R =H, alk or Oalk; X =--COOR 1 , --CONHR 2 or --NR 3 COR 4 ) n in the azo coupling, the side reactions which form PCBs can be decidedly suppressed during synthesis of the pigments.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/j.jhazmat.2004.03.006
摘要:Wong KH, Tao S, Dawson R, Wong PK. Optimization of photocatalytic oxidation of 2,2',3,3'-tetrachlorobiphenyl. J Hazard Mater. 2004 Jun 18;109(1-3):149–55. doi: 10.1016/j.jhazmat.2004.03.006.
摘要:S116 | REFCCS | Collision Cross Section (CCS) Values from Literature | DOI:10.5281/zenodo.10932895
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). http://www.atsdr.cdc.gov/mrls/
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