CAS: 301-16-6; Scoparoside

📜在 Palladium 10% On Activated Carbon,氢气体系中,用 四氢呋喃,甲醇,乙醇 作为反应溶剂,化学反应生成 异金雀花素,金雀花素
参考文献:Biosynthesis Of Natural And Novel C-Glycosylflavones Utilising Recombinant Oryza Sativa C-Glycosyltransferase (Oscgt) And Desmodium Incanum Root Proteins
标题:Biosynthesis Of Natural And Novel C-Glycosylflavones Utilising Recombinant Oryza Sativa C-Glycosyltransferase (Oscgt) And Desmodium Incanum Root Proteins
摘要:The Rice C-Glycosyltransferase (Oscgt) Is One Of Only A Small Number Of Characterised Plant C-Glycosyltransferases (Cgt) Known. The Enzyme C-Glucosylates A 2-Hydroxyflavanone Substrate With Udp-Glucose As The Sugar Donor To Produce C-Glucosyl-2-Hydroxyflavanones. We Tested Substrate Specificity Of The Enzyme,Using Synthetic 2-Hydroxyflavanones,And Showed It Has The Potential To Generate Known Natural Cgfs That Have Been Isolated From Rice And Also Other Plants. In Addition,We Synthesised Novel,Unnatural 2-Hydroxyflavanone Substrates To Test The B-Ring Chemical Space Of Substrate Accepted By The Oscgt And Demonstrated The Oscgt Capacity As A Synthetic Reagent To Generate Significant Quantities Of Known And Novel Cgfs. Many B-Ring Analogues Are Tolerated Within A Confined Steric Limit. Finally The Oscgt Was Used To Generate Novel Mono-C-Glucosyl-2-Hydroxyflavanones As Putative Biosynthetic Intermediates To Examine The Potential Of Desmodium Incanum Biosynthetic Cgts To Produce Novel Di-C-Glycosylflavones,Compounds Implicated In The Allelopathic Biological Activity Of Desmodium Against Parasitic Weeds From The Striga Genus. (C) 2016 The Authors. Published By Elsevier Ltd.
DOI:10.1016/j.Phytochem.2016.02.013